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Mesna

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Identification
Molecular formula
C2H4NaO3S
CAS number
19767-45-4
IUPAC name
2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine
State
State

At room temperature, Mesna exists in a solid state. It is stable under ordinary conditions and is generally utilized in its solid form but can be dissolved in solvents like water for different pharmaceutical or chemical applications.

Melting point (Celsius)
-3.00
Melting point (Kelvin)
270.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
164.21g/mol
Molar mass
164.2120g/mol
Density
1.5240g/cm3
Appearence

Mesna typically appears as a white crystalline solid. It is crystalline in nature and may have a certain sheen or luster characteristic of many such solids. As a reagent or medication, it is commonly handled in powdered form but may also be found within liquid solutions for specific applications.

Comment on solubility

Solubility of 2,5-Dihydroxybenzenesulfonic Acid and N-Ethylethanamine

The solubility of compounds is a critical factor in determining their utility in various applications. For 2,5-dihydroxybenzenesulfonic acid (often referred to as a sulfonic acid derivative), we observe notable properties:

  • Water Solubility: Due to the presence of sulfonic acid groups, 2,5-dihydroxybenzenesulfonic acid is highly soluble in water. This characteristic arises from the ability of the sulfonic acid group to ionize in aqueous solutions, allowing for strong interactions with water molecules.
  • Polarity and Interaction: The hydroxyl (-OH) groups contribute to the compound's polarity, enhancing its solubility in polar solvents. Thus, it can readily dissolve in alcohols and other polar organic solvents.
  • pH Dependence: The solubility can be affected by the pH of the solution, with higher solubility observed at lower pH levels where the sulfonic group is fully protonated.

In contrast, N-ethylethanamine (also known as ethanolamine) presents a different solubility profile:

  • Amine Characteristics: As a secondary amine, N-ethylethanamine is soluble in both water and organic solvents due to its ability to form hydrogen bonds.
  • Effect of Alkyl Group: The ethyl group contributes to some hydrophobic characteristics, which may slightly reduce its solubility in water compared to primary amines.
  • Miscibility: This compound can mix easily with alcohols and ethers due to its polar nature, facilitating its use in various formulations.

In summary, the solubility of both 2,5-dihydroxybenzenesulfonic acid and N-ethylethanamine is significantly influenced by their respective functional groups, polarity, and environmental factors such as pH. Understanding these properties is key for their applications in chemical synthesis and formulation.

Interesting facts

Insights into 2,5-Dihydroxybenzenesulfonic Acid and N-Ethylethanamine

2,5-Dihydroxybenzenesulfonic acid is a fascinating compound known for its unique structure and properties. Here are some interesting facts about this compound:

  • Functional versatility: This compound features both hydroxyl and sulfonic acid groups, making it a valuable intermediate in organic synthesis.
  • Role in dyes: It is particularly important in the production of azo dyes, which are widely used in textiles and inks. The presence of multiple hydroxy groups aids in the dyeing process.
  • pH regulation: Due to its acid nature, it is utilized in various formulations that require pH adjustment, notably in laboratory settings.

N-Ethylethanamine, on the other hand, adds a different perspective to our understanding of amines:

  • Amine applications: N-Ethylethanamine is a primary amine that plays a critical role in the synthesis of pharmaceuticals and agrochemicals.
  • Safeguards in production: As a building block in organic chemistry, it is essential for creating larger, more complex molecules.
  • Toxicity considerations: While useful, it is important to handle this compound with care due to its potential toxicity, especially in concentrated forms.

Both of these compounds highlight the importance of functional groups in determining chemical behavior and application. In the words of a notable chemist, "The beauty of chemistry lies in the complexity of simplicity." Understanding such compounds not only enriches our knowledge but also broadens the horizons of industrial applications.

Synonyms
Etamsylate
ETHAMSYLATE
2624-44-4
Cyclonamine
Aglumin
Ciclonamina
Dicynene
Etamsilato
Eselin
Etamsylatum
Etamsilate
MD 141
E 141
Diethylamine dobesilate
Etamsylatum [INN-Latin]
Etamsilato [INN-Spanish]
EINECS 220-090-7
UNII-24YL531VOH
24YL531VOH
DTXSID4045559
Diethylammonium 2,5-dihydroxybenzenesulfonate
MD-141
2,5-Dihydroxybenzenesulfonic acid compound with diethylamine (1:1)
Diethylammonium cyclohexadien-4-ol-1-one-4-sulfonate
DTXCID2025559
E-141
Diidroxi-1,4-benzenesulfonato-3-di-etilammonium
Etamsylatum (INN-Latin)
Etamsilato (INN-Spanish)
ETAMSYLATE (MART.)
ETAMSYLATE [MART.]
ETAMSYLATE (EP MONOGRAPH)
ETAMSYLATE [EP MONOGRAPH]
B02BX01
220-090-7
Ethamsylate [USAN]
Etamsylate [INN]
diethylamine 2,5-dihydroxybenzenesulfonate
2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine (1:1)
Altodor
2,5-Dihydroxybenzenesulfonic acid N-ethylethanamine
Ethamsylate (USAN)
Nordihydrocapsaicin-d3
NCGC00017041-01
Dicynone
CAS-2624-44-4
2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine
Ciclonamina [Italian]
N-[(4-Hydroxy-3-methoxyphenyl)methyl]-7-methyl-octanamide-d3; 7-Methyl-N-vanillyl-octanamide-d3; Norhydrocapsaicin-d3
MFCD00867499
Diidroxi-1,4-benzenesulfonato-3-di-etilammonium [Italian]
Ethamsylate (Standard)
Etamsylate (JAN/INN)
ETAMSYLATE [JAN]
ETHAMSYLATE [MI]
ETAMSILATE [WHO-DD]
SCHEMBL34303
CHEMBL1514715
CHEBI:31563
HY-B1074R
HMS1571K11
HMS2098K11
HMS3652I22
HMS3715K11
BCP12254
HY-B1074
Tox21_110752
s4152
AKOS005267176
CCG-221015
CS-4630
DB13483
FD22852
KS-1169
NCGC00017041-02
NCGC00017041-04
AC-32031
Etamsylate 100 microg/mL in Acetonitrile
diethylamine 2,5-dihydroxy benzene sulfonate
E1145
NS00083251
SW197271-3
D01282
F20533
SR-01000838306
Q2000876
SR-01000838306-2
2,5-Dihydroxybenzene- sulfonic Acid Diethylamine Salt
2,5-Dihydroxybenzenesulfonic Acid N-Ethylethanamine Salt
Etamsylate;2,5-Dihydroxybenzene-sulfonic acid diethylamine salt;Diethylamine 2,5-dihydroxybenzenesulfonate;Aglumin