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Amiodarone

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Identification
Molecular formula
C25H29I2NO3
CAS number
1951-25-3
IUPAC name
(2,5-dimethyl-3-furyl)-(4-hydroxy-3,5-diiodo-phenyl)methanone
State
State

Amiodarone is typically a solid at room temperature. It is usually handled as a fine powder.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
656.00
Boiling point (Kelvin)
929.00
General information
Molecular weight
645.32g/mol
Molar mass
645.3200g/mol
Density
2.6000g/cm3
Appearence

Amiodarone typically appears as a white or slightly yellow crystalline powder. Its color can vary slightly depending on its purity and the presence of any impurities.

Comment on solubility

Solubility of (2,5-dimethyl-3-furyl)-(4-hydroxy-3,5-diiodo-phenyl)methanone

The solubility of (2,5-dimethyl-3-furyl)-(4-hydroxy-3,5-diiodo-phenyl)methanone can be influenced by several factors such as its molecular structure and the presence of functional groups. This compound features hydrophobic furan and aromatic rings as well as a polar hydroxyl group. As a result, its solubility is:

  • Low to Moderate in Water: The overall structure suggests limited solubility in water due to the dominance of non-polar character from the furan and aromatic components.
  • Better in Organic Solvents: The compound is likely to dissolve more readily in organic solvents such as ethanol or DMSO, which can stabilize its hydrophobic parts.
  • Temperature Dependent: Solubility may increase with temperature, which often helps to dissolve organic compounds.

In summary, the solubility of (2,5-dimethyl-3-furyl)-(4-hydroxy-3,5-diiodo-phenyl)methanone is heavily influenced by its molecular interactions, and understanding these can aid in predicting its behavior in various solutions.

Interesting facts

Interesting Facts about (2,5-dimethyl-3-furyl)-(4-hydroxy-3,5-diiodo-phenyl)methanone

This compound presents a remarkable fusion of organic chemistry elements, showcasing both furyl and phenolic moieties. Here are some engaging insights about it:

  • Functional Diversity: The presence of the furyl group indicates potential aromaticity, while the phenol structure contributes to its reactivity through hydroxyl functionalities.
  • Iodine Influence: It’s intriguing to note that the inclusion of diiodo substituents on the phenyl ring can significantly alter the electronic properties and enhance its effectiveness in various chemical reactions.
  • Applications: Compounds like this one may exhibit interesting biological activities, particularly in fields such as medicinal chemistry, where derivatives are often explored for their potential therapeutic effects.
  • Synthetic Utility: This complex structure serves as a valuable scaffold in synthetic organic chemistry, allowing scientists to develop novel compounds with tailored properties.
  • Chemical Behavior: The interplay between the furyl and the diiodophenyl substructures could result in intriguing chemical interactions, leading to varied reactivity that is worth investigating.

Overall, (2,5-dimethyl-3-furyl)-(4-hydroxy-3,5-diiodo-phenyl)methanone exemplifies the creative potential of chemistry, prompting further exploration into both its synthesis and practical applications.

Synonyms
Furidarone
4662-17-3
Furidarone [INN]
Furidarona
3,5-Diiodo-4-hydroxyphenyl 2,5-dimethyl-3-furyl ketone
(2,5-dimethylfuran-3-yl)-(4-hydroxy-3,5-diiodophenyl)methanone
F93C12LM0D
2,5-Dimethyl-3-furyl-4-hydroxy-3,5-diiodophenyl ketone
Furodiarone
Furidaronum
Furidaronum [INN-Latin]
Furidarona [INN-Spanish]
EINECS 225-106-6
DB 136
UNII-F93C12LM0D
SCHEMBL2108387
CHEMBL2107414
2,5-Dimethyl-3-furyl-(4-hydroxy-3,5-diiodophenyl)ketone
DTXSID50196886
JCKOFFJWBOVAAV-UHFFFAOYSA-N
Ketone, 2,5-dimethyl-3-furyl 4-hydroxy-3,5-diiodophenyl-
KETONE, 3,5-DIIODO-4-HYDROXYPHENYL 2,5-DIMETHYL-3-FURYL
Methanone, (2,5-dimethyl-3-furanyl)(4-hydroxy-3,5-diiodophenyl)
AKOS040751879
NS00031618
Q27277830