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2,5-Dimethylpiperazine

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Identification
Molecular formula
C6H14N2
CAS number
15592-52-8
IUPAC name
2,5-dimethylpiperazine
State
State

At room temperature, 2,5-dimethylpiperazine is most commonly found in a liquid state but can also exist as a solid if the temperature drops below its melting point.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
155.00
Boiling point (Kelvin)
428.15
General information
Molecular weight
114.19g/mol
Molar mass
114.1890g/mol
Density
0.8957g/cm3
Appearence

2,5-Dimethylpiperazine typically appears as a colorless to pale yellow liquid. It may also occasionally appear as a crystalline solid depending on the conditions. It has a faint, characteristic amine odor.

Comment on solubility

Solubility of 2,5-Dimethylpiperazine

2,5-Dimethylpiperazine, with the chemical formula C6H14N2, exhibits interesting solubility characteristics that make it relevant in various chemical applications. Generally, it is known to be:

  • Soluble in Water: This compound is quite soluble in water due to the presence of nitrogen atoms that can form hydrogen bonds with water molecules.
  • Soluble in Organic Solvents: It readily dissolves in organic solvents such as ethanol and acetone, owing to its hydrophobic methyl groups which interact favorably with non-polar environments.

Furthermore, the solubility of 2,5-Dimethylpiperazine can be influenced by several factors, including:

  1. Temperature: Increased temperature typically enhances solubility.
  2. pH Levels: Changes in acidity or basicity can affect ionic forms of the compound, altering solubility.

In summary, 2,5-dimethylpiperazine is significantly soluble in both polar and non-polar solvents, making it a versatile compound in chemical syntheses and formulations. Understanding its solubility profile is essential for optimizing its use in various scientific and industrial processes.

Interesting facts

Interesting Facts about 2,5-Dimethylpiperazine

2,5-Dimethylpiperazine is an intriguing compound that falls within the category of piperazines, which are a class of organic compounds featuring a six-membered ring containing two nitrogen atoms. This compound has garnered interest for a variety of applications and characteristics:

  • Chemical Structure: The presence of two methyl groups at the 2 and 5 positions of the piperazine ring enhances its steric and electronic properties, making it a versatile molecule in organic synthesis.
  • Pharmaceutical Applications: It acts as a building block in pharmaceutical chemistry, contributing to the synthesis of numerous biologically active compounds, including potential anti-cancer and anti-viral agents.
  • Research Tool: Scholars often utilize 2,5-dimethylpiperazine in studies related to receptor binding and biological activity, owing to its ability to modulate the activity of neurotransmitter receptors.
  • Ligand Properties: The compound also functions as a ligand in coordination chemistry, allowing it to bond with various metal ions and form stable complexes.

As noted by researchers, "the unique structural features of 2,5-dimethylpiperazine serve as a springboard for innovative drug development processes." Its significance in the scientific community highlights not only its utility but also the need for thorough investigation into its potential effects and mechanisms of action.

In summary, 2,5-dimethylpiperazine exemplifies how simple structural variations can usher in profound differences in chemical behavior and applicability, making it a subject worthy of study for both budding chemists and seasoned researchers alike.

Synonyms
2,5-DIMETHYLPIPERAZINE
106-55-8
Piperazine, 2,5-dimethyl-
EINECS 203-409-4
BRN 0079885
cis-2,5-Dimethylpiperazine
MFCD00005955
UNII-ZIZ1G1N25S
ZIZ1G1N25S
2,5-dimethylpiperazine, trans
1119702-25-8
DTXSID70861721
5-23-03-00304 (Beilstein Handbook Reference)
6284-84-0
(2R,5R)-2,5-DIMETHYL-PIPERAZINE
Piperazine, 2,5-dimethyl-, cis-
2,5-dimethyl piperazine
MFCD08686705
2,5-dimethyl-piperazine
SCHEMBL20893
DTXCID60810607
AC2834
BBL027547
STL352114
AKOS005203484
AB02818
AB48053
CS-11007
SY002107
SY260551
DB-015921
DB-016197
CS-0106273
NS00066786
EN300-81279
Q22079573
InChI=1/C6H14N2/c1-5-3-8-6(2)4-7-5/h5-8H,3-4H2,1-2H
203-409-4
818-483-9