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2,5-Dimethylpyrazine

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Identification
Molecular formula
C6H8N2
CAS number
123-32-0
IUPAC name
2,5-dimethylpyrazine
State
State

At room temperature, 2,5-dimethylpyrazine is in a liquid state.

Melting point (Celsius)
-12.20
Melting point (Kelvin)
260.95
Boiling point (Celsius)
155.90
Boiling point (Kelvin)
429.05
General information
Molecular weight
108.14g/mol
Molar mass
108.1410g/mol
Density
0.9784g/cm3
Appearence

2,5-Dimethylpyrazine is a colorless to pale yellow liquid with a distinctive, nutty odor. It is often used in flavors and fragrances due to its rich aroma.

Comment on solubility

Solubility of 2,5-Dimethylpyrazine

2,5-Dimethylpyrazine, with its distinctive structure, showcases interesting solubility properties that are influenced by its molecular characteristics. Primarily, this compound exhibits:

  • Moderate Solubility in Water: While pyrazine derivatives tend to have limited solubility in water, 2,5-dimethylpyrazine has a modest solubility due to the presence of methyl groups that assist in reducing the molecule's hydrophobic nature.
  • Higher Solubility in Organic Solvents: This compound is generally well soluble in various organic solvents such as ethanol, acetone, and chloroform. The non-polar characteristics imparted by the methyl groups facilitate its interactions with non-polar solvents.
  • Temperature Dependence: Like many organic compounds, the solubility of 2,5-dimethylpyrazine can increase with temperature, which enhances the energy available to overcome intermolecular forces.

It's noteworthy that the solubility can be affected by factors such as:

  1. Presence of Other Solutes: Solvents that contain polar or hydrogen-bonding functionalities can alter the solubility dynamics.
  2. pH Levels: Although 2,5-dimethylpyrazine is a neutral compound, the surrounding pH may influence the solubility of similar reactive species.

In summary, 2,5-dimethylpyrazine's solubility characteristics make it a unique compound, marking its importance in both chemical synthesis and applications in various fields, particularly in flavor and fragrance industries, where solubility plays a critical role in formulation.

Interesting facts

Interesting Facts about 2,5-Dimethylpyrazine

2,5-Dimethylpyrazine is an intriguing compound belonging to the class of pyrazines, which are aromatic heterocycles composed of nitrogen and carbon. Here are some fascinating insights into this unique compound:

  • Flavor and Aroma: 2,5-Dimethylpyrazine has a distinctive roasted, nutty aroma that makes it a valuable compound in the food industry. It is often used as a flavoring agent in products like coffee, chocolate, and certain savory foods.
  • Natural Occurrence: This compound is naturally found in various sources, including grilled meats and toasted nuts, contributing to the complex flavor profiles of these foods.
  • Synthetic Production: While it can be found naturally, 2,5-dimethylpyrazine is often synthesized for use in commercial applications. This is achieved through methods such as the condensation of α-ketocarboxylic acids or through reactions involving pyrazine itself.
  • Biological Activity: Some studies suggest that 2,5-dimethylpyrazine may have antibacterial properties, adding an interesting perspective on its potential health benefits and applications in food preservation.
  • Importance in Chemistry: As a substituted pyrazine, it serves as an important building block in organic synthesis and can be used to create a variety of other chemical compounds, showcasing the versatility of pyrazine derivatives.

In summary, 2,5-dimethylpyrazine is not only a significant flavor compound but also plays a promising role in various fields, including food science and synthetic organic chemistry. Its unique properties and applications make it a fascinating topic for further exploration!

Synonyms
2,5-DIMETHYLPYRAZINE
123-32-0
Pyrazine, 2,5-dimethyl-
2,5-Dimethyl-1,4-diazine
FEMA No. 3272
Ketine
V99Y0MUY1Q
NSC-49139
DTXSID6047652
RefChem:82971
DTXCID4027652
204-618-3
2,5-Dimethyl pyrazine
NSC 49139
2,5-Dimethylpiazine
2,5-Dimethylparadiazine
2,5-Dimethyl-pyrazine
MFCD00006147
PYRAZINE,2,5-DIMETHYL
CHEBI:89762
CCRIS 2929
2,5-Dimethylpyrazine (natural)
EINECS 204-618-3
UNII-V99Y0MUY1Q
AI3-60303
2.5-dimethylpyrazine
2, 5-Dimethylpyrazine
pyrazine, 2,5-dimethyl
SCHEMBL82304
SCHEMBL96015
2,5-Dimethylpyrazine, 98%
CHEMBL94709
SCHEMBL193055
orb1302555
SCHEMBL2938758
FEMA 3272
WLN: T6N DNJ B1 E1
2,5 and 2,6-dimethyl pyrazine
2,5-Dimethylpyrazine (Standard)
MSK2926
BCP08618
NSC49139
2,5-DIMETHYLPYRAZINE [FCC]
2,5-DIMETHYLPYRAZINE [FHFI]
HY-34439R
SBB058647
2,5-Dimethylpyrazine, >=98%, FG
AKOS003368403
CS-W019957
NCGC00184236-01
NCGC00184236-02
2,5-Dimethylpyrazine, analytical standard
AC-10703
AS-17251
HY-34439
DB-003236
2,5-Dimethylpyrazine (contains 2,6-isomer)
D1526
D2171
NS00012335
S3108
ST45024376
2,5-DIOXA-8-AZA-SPIRO[3,5]NONANE
EN300-20206
2,5-dimethylpyrazine and 2,6-dimethylpyrazine
23D320
P19770
F002729
Q27161950
F0001-0364
Z104477264
InChI=1/C6H8N2/c1-5-3-8-6(2)4-7-5/h3-4H,1-2H
25R