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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
2,6-bis[(4-hydroxy-3-methoxy-phenyl)methylene]cyclohexanone
State
State

At room temperature, curcumin is a solid.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.00
Boiling point (Celsius)
650.00
Boiling point (Kelvin)
923.00
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.2020g/cm3
Appearence

Curcumin is a bright yellow crystalline solid.

Comment on solubility

Solubility of 2,6-bis[(4-hydroxy-3-methoxy-phenyl)methylene]cyclohexanone

The solubility of 2,6-bis[(4-hydroxy-3-methoxy-phenyl)methylene]cyclohexanone can be quite interesting given its specific chemical structure. Here are some key aspects to consider regarding its solubility:

  • Polar vs. Non-Polar Solvent: This compound is likely soluble in polar solvents due to the presence of hydroxyl (-OH) groups, which can engage in hydrogen bonding.
  • Solubility in Water: Its solubility in water may be limited as the bulky cyclohexanone structure can hinder interaction with water molecules.
  • Organic Solvents: It is expected to show better solubility in organic solvents such as ethanol, acetone, or dichloromethane.

In general, the combination of hydrophilic and hydrophobic features in its structure means that while it may dissolve in certain solvents, it could also exhibit significant insolubility in others. Understanding these nuances is vital for applications in chemical synthesis and product formulations. In conclusion, the solubility behavior of this compound reflects a complex interplay of its structural characteristics.

Interesting facts

Interesting Facts about 2,6-bis[(4-hydroxy-3-methoxy-phenyl)methylene]cyclohexanone

This intriguing compound, known as 2,6-bis[(4-hydroxy-3-methoxy-phenyl)methylene]cyclohexanone, is a fascinating example within the realm of organic chemistry. It is often studied for its unique structural features and potential applications. Here are some notable aspects of this compound:

  • Structural Complexity: The molecule contains a cyclohexanone framework that is substituted with two methylene linkages and aromatic hydroxyl groups. This complexity contributes to its interesting reactivity and properties.
  • Phenolic Nature: The presence of hydroxy groups on the aromatic rings enhances the compound's potential as a phenolic antioxidant, making it of interest in various chemical and medicinal applications.
  • Color and Dyes: Due to its structurally unique composition, this compound is explored in dye chemistry, particularly in the synthesis of materials that possess vibrant colors and are stable under various conditions.
  • Biological Activity: Compounds of this type have shown promise in biological studies, particularly in their antioxidant properties, which may play a role in protecting cells from damage caused by free radicals.
  • Potential Applications: Beyond its use in dye production, research indicates potential applications in pharmaceuticals, as the structural similarities to other known medicinal compounds could lead to novel drug discoveries.

In conclusion, the exploration of 2,6-bis[(4-hydroxy-3-methoxy-phenyl)methylene]cyclohexanone not only highlights the beauty of organic molecular structures but also underscores the importance of such compounds in advancing scientific knowledge and practical applications. As we continue to study compounds like these, the possibilities for innovation and discovery in chemistry remain boundless.

Synonyms
Cyclovalone
Ciclovalona
Divanil
Beveno
Cyclovalone [INN]
Cyqualon
Cyclovalon
Cyclovalonum
Curcumoid
Cycvalon
Divanon
Flavugal
Tsikvalon
Vanidene
579-23-7
VANILONE
Divanillalcyclohexanone
CYCLOVALONE [MI]
NSC-26727
Cyclovalonum [INN-Latin]
Ciclovalona [INN-Spanish]
CYCLOVALONE [MART.]
UNII-6M4YJ3FA16
CYCLOVALONE [WHO-DD]
2,6-Divanillidenecyclohexanone
DIVANILLIDEN CYCLOHEXANONE
DTXSID7046386
Cyclohexanone, 2,6-vanillylidene-
EINECS 209-438-9
Cyclohexanone, 2,6-divanillylidene-
2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone
NSC 26727
BRN 2019082
AI3-26016
Cyclovalonum (INN-Latin)
Ciclovalona (INN-Spanish)
CYCLOVALONE (MART.)
4-08-00-03586 (Beilstein Handbook Reference)
Cyclohexanone, 2,6-bis((4-hydroxy-3-methoxyphenyl)methylene)-
DTXCID5026386
BMHPC
2,6-divanillylcyclohexanone
Cyclohexanone, 2,6-divanillylidene-(8CI)
2,6-bis((3-methoxy-4-hydroxyphenyl)methylene)cyclohexanone
Cyclohexanone, 2,6-bis((4-hydroxy-3-methoxyphenyl)methylene)-(9CI)
209-438-9
(2e,6e)-2,6-bis((4-hydroxy-3-methoxyphenyl)methylidene)cyclohexan-1-one
(2e,6e)-2,6-bis[(4-hydroxy-3-methoxyphenyl)methylidene]cyclohexan-1-one
2,6-Divanillylidenecyclohexanone
6M4YJ3FA16
Tsikvalon; Vanilone
2,6-bis[(4-hydroxy-3-methoxyphenyl)methylidene]cyclohexan-1-one
2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone;
2,6-Bis[(4-hydroxy-3-methoxyphenyl)methylene]cyclohexanone;
ChemDiv1_019429
(2Z,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone
2,6-divanillylidencyclohexanon
CHEMBL2362372
DHKKONBXGAAFTB-UHFFFAOYSA-N
AAA57923
DVC
AKOS034380226
NCI60_018490
NS00003338
Q27265138
2,6-Bis((4-hydroxy-3-methoxyphenyl)methylene)cyclohexanone
Cyclohexanone,2,6-bis[(4-hydroxy-3-methoxyphenyl)methylene]-