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2,6-Dichloro-N-cyclopropyl-N-ethylpyridine-4-carboxamide

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Identification
Molecular formula
C11H12Cl2N2O
CAS number
915288-13-0
IUPAC name
2,6-dichloro-N-cyclopropyl-N-ethyl-pyridine-4-carboxamide
State
State

The compound is in a solid state at room temperature, indicating its stability under ambient conditions without an inclination to readily dissolve or vaporize.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
285.12g/mol
Molar mass
285.1600g/mol
Density
1.3844g/cm3
Appearence

2,6-Dichloro-N-cyclopropyl-N-ethylpyridine-4-carboxamide appears as a crystalline solid. The precise appearance may vary slightly based on purity and specific formulation, but it typically presents as off-white to pale yellow in coloration.

Comment on solubility

Solubility of 2,6-Dichloro-N-cyclopropyl-N-ethyl-pyridine-4-carboxamide

The solubility of 2,6-dichloro-N-cyclopropyl-N-ethyl-pyridine-4-carboxamide can be influenced by various factors due to its complex structure. Here are some key aspects to consider:

  • Solvent Interaction: The solubility is likely to vary significantly between polar and non-polar solvents. The presence of the carboxamide group contributes to possible hydrogen bonding, suggesting increased solubility in polar solvents such as water or alcohols.
  • Temperature Effects: Typically, an increase in temperature can enhance solubility, particularly for solid compounds. In laboratory settings, assessing solubility at different temperatures may reveal critical insights.
  • pH Dependence: For compounds containing functional groups like carboxamides, the solubility may be pH-dependent. Changes in pH can affect protonation states, thus altering solubility behavior.
  • Structural Considerations: The cyclopropyl and ethyl groups in the compound may influence its hydrophobic characteristics, possibly making it less soluble in water but more soluble in organic solvents.

In conclusion, while precise solubility data may require empirical investigation, it is essential to consider these factors and utilize appropriate techniques to assess the solubility of this intriguing compound. As one saying goes, "The solvent is often the secret ingredient." This emphasizes the importance of solvent selection in the solubility assessment of chemical compounds.

Interesting facts

Interesting Facts about 2,6-Dichloro-N-cyclopropyl-N-ethyl-pyridine-4-carboxamide

2,6-Dichloro-N-cyclopropyl-N-ethyl-pyridine-4-carboxamide is a fascinating compound that showcases the intersection of organic chemistry and pharmacology. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features a pyridine ring, which is a fundamental structure in many biologically active molecules. The presence of multiple functional groups, including chloro and carboxamide, contributes to its unique chemical reactivity.
  • Applications: Due to its specific substitutions, this compound may possess various biological activities, making it a subject of interest in medicinal chemistry for potential drug development.
  • Chlorine Atoms: The dichloro substitutions at the 2 and 6 positions of the pyridine ring can significantly influence the pharmacokinetics and pharmacodynamics of the molecule, potentially enhancing its therapeutic efficacy.
  • Cyclopropyl and Ethyl Groups: The incorporation of cyclopropyl and ethyl groups provides unique steric and electronic properties, which can affect binding interactions with biological targets.
  • Research Potential: As a relatively complex organic molecule, it offers numerous opportunities for synthetic chemists to explore innovative synthetic methodologies and techniques.

In summary, 2,6-dichloro-N-cyclopropyl-N-ethyl-pyridine-4-carboxamide is not just another chemical entity, but a compound that embodies the rich complexity and potential of organic chemistry. Its unique structure and possible applications can spark further research, leading to exciting discoveries in the fields of pharmaceuticals and materials science.

Synonyms
Abbott-28440
2,6-Dichloro-N-cyclopropyl-N-ethylisonicotinamide
JOT6TUR9NG
UNII-JOT6TUR9NG
BRN 0402748
ISONICOTINAMIDE, 2,6-DICHLORO-N-CYCLOPROPYL-N-ETHYL-
DTXSID90174300
2,6 DICHLORO-N-CYCLOPROPYL-N-ETHYLISONICOTINAMIDE
4-PYRIDINECARBOXAMIDE, 2,6-DICHLORO-N-CYCLOPROPYL-N-ETHYL-
DTXCID3096791
RefChem:199313
20373-56-2
2,6-dichloro-N-cyclopropyl-N-ethylpyridine-4-carboxamide
Oprea1_536125
AKOS009163235
Q27281611