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2,6-dichloro-N'-hydroxy-benzamidine

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Identification
Molecular formula
C7H6Cl2N2O
CAS number
66644-81-3
IUPAC name
2,6-dichloro-N'-hydroxy-benzamidine
State
State

At room temperature, 2,6-dichloro-N'-hydroxy-benzamidine is in a solid state. It is stable under normal temperatures and pressures.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
477.80
Boiling point (Kelvin)
750.95
General information
Molecular weight
205.03g/mol
Molar mass
205.0230g/mol
Density
1.5400g/cm3
Appearence

2,6-Dichloro-N'-hydroxy-benzamidine typically appears as a pale yellow solid. It is crystalline in nature, and the color may range from white to light yellow, depending on the degree of purity and form of crystallization.

Comment on solubility

Solubility of 2,6-Dichloro-N'-hydroxy-benzamidine

The solubility of 2,6-dichloro-N'-hydroxy-benzamidine can be influenced by various factors. When discussing its solubility, it is crucial to consider the following aspects:

  • Polarity: The presence of hydroxyl (-OH) groups tends to increase the polarity of a compound, facilitating its solubility in polar solvents like water.
  • Hydrogen bonding: The hydroxyl group can engage in hydrogen bonding, which may enhance solubility in aqueous solutions compared to non-polar solvents.
  • Halogen influence: The two chlorine atoms may influence the overall solubility, as halogens can impact intermolecular interactions.
  • pH dependence: The solubility of this compound may also vary with pH, particularly due to the presence of the amidine functional group, which can exist in different protonation states.

In summary, while 2,6-dichloro-N'-hydroxy-benzamidine is likely to be more soluble in polar solvents due to its functional groups, its specific solubility will ultimately depend on solvent choice and environmental conditions. As a rule of thumb, "like dissolves like" – so expect better solubility in solvents that share similar polar characteristics.

Interesting facts

Interesting Facts about 2,6-Dichloro-N'-hydroxy-benzamidine

2,6-Dichloro-N'-hydroxy-benzamidine is a fascinating compound recognized for its unique structure and potential applications in various fields. Here are some intriguing insights into this compound:

  • Pharmaceutical Relevance: This compound has garnered interest in medicinal chemistry due to its potential role as a pharmacological agent. Research has suggested that modifications in its structure can lead to variations in biological activity, opening avenues for drug development.
  • Enzyme Inhibition: Studies indicate that 2,6-dichloro-N'-hydroxy-benzamidine exhibits the ability to inhibit specific enzymes, which can be pivotal in the treatment of certain diseases. Its mechanism of action often involves the formation of * enzyme-inhibitor complexes, which explains its potential as a therapeutic agent.
  • Research Applications: Beyond medicinal uses, this compound is also utilized in scientific research, particularly in studies focused on enzyme kinetics and drug design. It serves as a model compound to understand the relationship between structure and bioactivity.
  • Environmental Considerations: Like many chemical compounds, the environmental impact of 2,6-dichloro-N'-hydroxy-benzamidine is under scrutiny. Understanding its behavior in different environments is crucial for assessing its safety and toxicity levels.
  • Synthetic Pathways: The synthesis of 2,6-dichloro-N'-hydroxy-benzamidine can involve various methodologies, showcasing the diversity of chemical reactions. This adaptability is vital for scientists looking to optimize production for research or industrial applications.

In summary, 2,6-dichloro-N'-hydroxy-benzamidine is more than just a chemical formula; it represents a critical junction of chemistry and pharmacology that inspires ongoing scientific exploration. Researchers continue to unveil its mysteries, making it a significant subject within the chemical community. As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This compound is a perfect example of how one idea can lead to countless discoveries.

Synonyms
2,6-dichloro-N'-hydroxybenzene-1-carboximidamide
RefChem:445438
820-679-4
23505-21-7
2,6-dichloro-N'-hydroxybenzenecarboximidamide
MFCD00221076
2,6-Dichlorobenzamidoxime
SCHEMBL102502
SCHEMBL1855925
DTXSID00274941
MULRGOOZFNLPFF-UHFFFAOYSA-N
YAA50521
AKOS030752785
Benzenecarboximidamide, 2,6-dichloro-N'-hydroxy-
2,6-bis(chloranyl)-N'-oxidanyl-benzenecarboximidamide