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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
(2,6-diethylphenyl) 2-(diethylamino)propanoate
State
State
Lidocaine is typically found as a solid in its pure form at room temperature. However, it is frequently used in aqueous solution form for medical injections and topical applications.
Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. The compound is often available in the form of aqueous solutions for medical use.

Comment on solubility

Solubility of (2,6-diethylphenyl) 2-(diethylamino)propanoate

The solubility of (2,6-diethylphenyl) 2-(diethylamino)propanoate is influenced by several factors including its chemical structure and the polarity of the solvent used. This compound, with a complex organic composition, presents interesting solubility characteristics:

  • Polarity: As an ester, it may exhibit moderate solubility in polar solvents, but has potential for higher solubility in organic solvents like ethanol or acetone.
  • Hydrogen Bonding: The presence of the diethylamino group can interact with solvents that are capable of hydrogen bonding, enhancing solubility in such environments.
  • Temperature Dependence: It is important to note that solubility can change with temperature; an increase in temperature often results in increased solubility for organic compounds.

To summarize, while the solubility of (2,6-diethylphenyl) 2-(diethylamino)propanoate can vary significantly depending on the solvent and conditions, it tends to be more soluble in non-polar to moderately polar organic solvents due to its ester and amine functional groups. This makes it suitable for use in various chemical applications where solubility is a key factor.

Interesting facts

Interesting Facts About (2,6-diethylphenyl) 2-(diethylamino)propanoate

(2,6-diethylphenyl) 2-(diethylamino)propanoate is a fascinating chemical compound that belongs to the class of esters and plays a significant role in medicinal chemistry.

Key Characteristics:

  • Pharmaceutical Applications: This compound has potential applications in the field of pharmaceuticals, particularly as a novel drug scaffold. Its unique structure allows it to interact with various biological targets.
  • Structure-Activity Relationship: The presence of diethylamino and diethyl groups may enhance lipid solubility, making it an interesting candidate for studies on bioavailability and metabolic pathways.
  • Synthetic Flexibility: The synthesis of (2,6-diethylphenyl) 2-(diethylamino)propanoate can allow for modifications that can lead to various analogs, opening avenues for research and development.

Chemistry Insights:

Scientists often emphasize the importance of understanding the structure-function relationship in drug design. As a compound with both aromatic and aliphatic structures, this compound can provide insights into how modifications can impact biological activity.

In Conclusion:

The exploration of (2,6-diethylphenyl) 2-(diethylamino)propanoate offers an exciting opportunity for research into new therapeutics and allows chemists to expand their understanding of ester-based compounds. As with many compounds in medicinal chemistry, the journey from the lab bench to clinical application is filled with potential and discovery.