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2,6-Difluorobenzoic acid

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Identification
Molecular formula
C7H4F2O2
CAS number
385-00-2
IUPAC name
2,6-difluorobenzoic acid
State
State

2,6-Difluorobenzoic acid is a solid at room temperature. Its crystalline nature and solid state make it suitable for handling and storage in laboratory settings.

Melting point (Celsius)
173.50
Melting point (Kelvin)
446.65
Boiling point (Celsius)
259.00
Boiling point (Kelvin)
532.15
General information
Molecular weight
172.12g/mol
Molar mass
172.1150g/mol
Density
1.4801g/cm3
Appearence

2,6-Difluorobenzoic acid typically appears as a white crystalline solid under standard conditions. It is a derivative of benzoic acid where two fluorine atoms are substituted at the 2nd and 6th positions of the benzene ring.

Comment on solubility

Solubility of 2,6-Difluorobenzoic Acid

2,6-difluorobenzoic acid, with the chemical formula C7H4F2O2, displays moderate solubility characteristics that are influenced by its molecular structure. Here are some key points regarding its solubility:

  • Aqueous Solubility: This compound has a certain degree of solubility in water due to the presence of the carboxylic acid group, which can ionize and interact with water molecules.
  • Interaction with Polar Solvents: 2,6-difluorobenzoic acid shows enhanced solubility in polar solvents like ethanol and methanol, aided by hydrogen bonding capabilities.
  • Organic Solvents: Conversely, it may have lower solubility in non-polar organic solvents, which lack the ability to interact significantly with the polar functionalities of the molecule.
  • Temperature Effects: Generally, as temperature increases, solubility in both polar and non-polar solvents may improve, providing greater dissolution rates.

In summary, while 2,6-difluorobenzoic acid exhibits **soluble characteristics** in specific environments, its solubility can fluctuate based on solvent type and temperature, presenting unique opportunities for various applications in chemical research and industry.

Interesting facts

Interesting Facts about 2,6-Difluorobenzoic Acid

2,6-Difluorobenzoic acid is an intriguing compound that presents a unique blend of chemical properties and applications. Here are some key points that highlight its significance:

  • Fluorine Substitution: The presence of fluorine atoms at the 2 and 6 positions on the aromatic ring enhances the compound's chemical reactivity and contributes to its unique physical properties. This substitution can affect how the compound interacts with other substances, making it a valuable tool in chemical synthesis.
  • Role in Pharmaceutical Research: 2,6-Difluorobenzoic acid serves as a potential building block in the synthesis of ligands and other important pharmaceutical intermediates. The fluorine atoms can modulate biological activity, making it an interesting candidate for drug design.
  • Polarity: The introduction of fluorine increases the polarity of the molecule, which can enhance its solubility in polar solvents. This characteristic is particularly useful in various chemical reactions and extractions where solubility is a concern.
  • Environmental Impact: As with many fluorinated compounds, it's important to consider the environmental implications of its use. While some fluorine-containing compounds can be persistent in the environment, 2,6-difluorobenzoic acid is generally viewed as less harmful, presenting fewer risks of bioaccumulation.
  • Applications in Material Science: Beyond its use in pharmaceuticals, 2,6-difluorobenzoic acid can also be explored in the realm of material science. Its unique properties may lead to advancements in the design of new materials with specific characteristics suitable for various applications.

In summary, 2,6-difluorobenzoic acid is not merely a chemical compound but a focal point in various scientific discussions. As researchers delve into its properties and applications, it remains a compound of interest in both academic and industrial chemistry.

Synonyms
2,6-DIFLUOROBENZOIC ACID
385-00-2
Benzoic acid, 2,6-difluoro-
2,6-Difluorobenzoicacid
BRN 0973774
EINECS 206-856-3
MFCD00002411
NSC 126584
95B9M9KUY5
2,6-difluorobenzoate
AI3-63060
NSC-126584
DTXSID7075391
3-09-00-01330 (Beilstein Handbook Reference)
DIFLUOROBENZOIC ACID, 2,6-
2,6-difluorobenzoate calcium dihydrate
2,6-difluoro benzoic acid
NSC126584
Benzoic acid,6-difluoro-
2,6,-difluorobenzoic acid
2,6-difluoro-benzoic acid
Benzoic acid, 2,6difluoro
UNII-95B9M9KUY5
SCHEMBL260553
DTXCID4039520
2,6-Difluorobenzoic acid, 98%
CS-M0554
STK802604
TD1186
AKOS000119515
AC-2898
BS-3869
CGA 149776
FD03493
SY003297
DB-015928
D1629
NS00015499
EN300-20036
A856661
AN-584/43306766
F2191-0055
Z104476530
206-856-3