Skip to main content

Esculetin

ADVERTISEMENT
Identification
Molecular formula
C10H8O4
CAS number
305-01-1
IUPAC name
2,6-dihydroxy-4-methyl-chromen-7-one
State
State

Esculetin is typically a solid at room temperature.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.00
Boiling point (Celsius)
386.00
Boiling point (Kelvin)
659.00
General information
Molecular weight
178.17g/mol
Molar mass
178.1420g/mol
Density
1.6310g/cm3
Appearence

Esculetin, also known as 6,7-dihydroxycoumarin, appears as a white to light tan crystalline powder. It is known for its crystalline nature and is often used in biochemical applications.

Comment on solubility

Solubility of 2,6-Dihydroxy-4-methyl-chromen-7-one

2,6-Dihydroxy-4-methyl-chromen-7-one, a flavonoid compound, exhibits interesting solubility characteristics influenced by its structural features. As a general rule, the solubility of organic compounds like this one can vary **significantly based on the solvent** used.

Here are some key points regarding the solubility of this compound:

  • Polar Solvents: 2,6-Dihydroxy-4-methyl-chromen-7-one is expected to dissolve more readily in polar solvents such as water or ethanol due to the presence of hydroxyl (-OH) groups that can form hydrogen bonds.
  • Non-Polar Solvents: The compound may demonstrate lower solubility in non-polar solvents such as hexane or benzene, due to its polar functional groups that do not interact favorably with non-polar environments.
  • Temperature Effect: Generally, increasing temperature can enhance solubility, so heating the solvent could aid in dissolving this flavonoid.
  • pH Influence: The solubility may also be pH-dependent, as changes in acidity can affect the ionization of hydroxyl groups, potentially increasing solubility in alkaline conditions.

In summary, the solubility of 2,6-dihydroxy-4-methyl-chromen-7-one is dictated by a combination of **polarity**, **temperature**, and **pH**, making it versatile for use in various applications depending on the chosen solvent environment.

Interesting facts

Interesting Facts about 2,6-Dihydroxy-4-methyl-chromen-7-one

2,6-Dihydroxy-4-methyl-chromen-7-one, commonly known as a flavonoid, is part of a larger group of chemical compounds that are prevalent in plant life. Flavonoids are known for their diverse range of biological activities and health benefits. Here are some intriguing facts about this compound:

  • Natural Sources: This compound is found in various plants, where it plays key roles in their coloration and protection against UV radiation.
  • Health Benefits: Flavonoids, including this compound, are recognized for their antioxidant properties. They may help combat oxidative stress and reduce the risk of chronic diseases.
  • Research Interest: Scientists are actively investigating this compound for its potential anti-inflammatory and antibacterial properties, paving the way for new therapeutic applications.
  • Structure and Function: Its unique chromen-7-one structure contributes to its lively interactions within biological systems, making it a fascinating subject of study in medicinal chemistry.

As reported in various research studies, compounds like 2,6-dihydroxy-4-methyl-chromen-7-one not only enhance our understanding of plant biochemistry but also inspire potential innovations in drug development. The quote from renowned chemist Robert H. Grubbs resonates well here: "Chemistry is the science of matter and its transformations." With continuous exploration, the transformations and applications of this flavonoid may unlock new frontiers in health and wellness.


In conclusion, 2,6-dihydroxy-4-methyl-chromen-7-one exemplifies the intricate connections between chemistry, nature, and human health, showcasing the importance of flavonoids not just in the plant world, but also in our daily lives.