Skip to main content

Orphenadrine

ADVERTISEMENT
Identification
Molecular formula
C18H23NO3
CAS number
83-98-7
IUPAC name
(2,6-dimethoxyphenyl) 2-(diethylamino)propanoate
State
State

Orphenadrine is usually in a solid state at room temperature.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
348.00
Boiling point (Kelvin)
621.15
General information
Molecular weight
265.36g/mol
Molar mass
265.3570g/mol
Density
1.0000g/cm3
Appearence

Orphenadrine is typically found as a white, crystalline powder. It is odourless and tasteless.

Comment on solubility

Solubility of (2,6-dimethoxyphenyl) 2-(diethylamino)propanoate

The solubility of (2,6-dimethoxyphenyl) 2-(diethylamino)propanoate can be described as follows:

  • Polar vs Nonpolar Solubility: This compound contains both polar and nonpolar characteristics due to the presence of the diethylamino group and the aromatic methoxy substituents. Therefore, it is likely to exhibit a moderate solubility in polar solvents like water, but significantly better solubility in organic solvents such as ethanol and dichloromethane.
  • Temperature Dependency: As with many organic compounds, the solubility may increase with temperature. Observations show that dissolving the compound at elevated temperatures often leads to improved solubility.
  • pH Influence: The solubility in aqueous solutions can also be influenced by pH. In more acidic or basic environments, the ionization of the diethylamino group can enhance solubility due to increased polarity.
  • Common Solvents: Solvents that typically dissolve similar compounds include:
    • Ethanol
    • Acetone
    • Dichloromethane
    • Dimethyl sulfoxide (DMSO)

In conclusion, understanding the solubility profile of (2,6-dimethoxyphenyl) 2-(diethylamino)propanoate is essential for applications in pharmaceutical formulations, as it affects both bioavailability and efficacy. The interplay of temperature, solvent type, and pH makes this compound particularly interesting for solubility studies.

Interesting facts

Interesting Facts about (2,6-dimethoxyphenyl) 2-(diethylamino)propanoate

(2,6-dimethoxyphenyl) 2-(diethylamino)propanoate, commonly known in research settings for its unique structure, has garnered attention due to its intriguing properties and potential applications. Here are some noteworthy aspects of this chemical compound:

  • Diverse Applications: This compound has been explored for its potential use in pharmaceutical formulations, particularly in drug delivery systems and medication development.
  • Substituent Significance: The presence of diethylamino and dimethoxy groups in its structure can affect its pharmacological properties, impacting solubility and biological activity.
  • Synthetic Route: The synthesis of this compound involves notable organic reactions, demonstrating important principles in synthetic chemistry, such as nucleophilic substitutions and esterifications.
  • Research Interest: Scientists are interested in its activity against various biological targets, including its potential effect on the nervous system, making it a subject of study in neuropharmacology.

As we delve deeper into chemical compounds like (2,6-dimethoxyphenyl) 2-(diethylamino)propanoate, we are reminded that the exploration of molecular diversity can lead to significant advancements in science and medicine. The study of such compounds highlights the complexity and beauty of organic chemistry.

Synonyms
SCHEMBL7143136