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N-Nitrosopiperidine

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Identification
Molecular formula
C7H14N2O
CAS number
100-75-4
IUPAC name
2,6-dimethyl-1-nitroso-piperidine
State
State

At room temperature, N-Nitrosopiperidine is generally a liquid. It is soluble in organic solvents and may slowly react with water over time.

Melting point (Celsius)
-6.50
Melting point (Kelvin)
266.65
Boiling point (Celsius)
214.20
Boiling point (Kelvin)
487.35
General information
Molecular weight
114.17g/mol
Molar mass
114.1680g/mol
Density
0.9389g/cm3
Appearence

N-Nitrosopiperidine typically appears as a colorless to yellowish liquid. It may sometimes be described as having a slight, characteristic odor. Upon prolonged exposure to air or light, it can darken in color.

Comment on solubility

Solubility of 2,6-dimethyl-1-nitroso-piperidine

The solubility of 2,6-dimethyl-1-nitroso-piperidine is an intriguing aspect that showcases its unique chemical behavior. This compound exhibits varying degrees of solubility depending on the solvent used. Here are some key points to consider:

  • Polar Solvents: In polar solvents such as water, solubility is generally limited due to the non-polar characteristics imparted by the hydrocarbon structure of the piperidine ring.
  • Non-Polar Solvents: 2,6-dimethyl-1-nitroso-piperidine demonstrates significantly enhanced solubility in non-polar solvents like hexane or toluene, which can effectively solvate the compound due to similar interactions.
  • Temperature Effects: An increase in temperature can lead to improved solubility for many organic compounds, making this a crucial factor when considering dissolving 2,6-dimethyl-1-nitroso-piperidine.
  • Practical Considerations: Laboratory conditions and specific applications often dictate the choice of solvent. Thus, understanding the solubility profile is essential for effective use in chemical reactions or formulations.

In summary, while 2,6-dimethyl-1-nitroso-piperidine may have limited solubility in polar environments, its affinity for non-polar solvents coupled with temperature influence creates an interesting landscape for its applications.

Interesting facts

Interesting Facts about 2,6-Dimethyl-1-nitroso-piperidine

2,6-Dimethyl-1-nitroso-piperidine is a fascinating compound known for its unique structure and intriguing applications in the field of chemistry. Here are some key points to consider:

  • Structure and Configuration: This compound features a piperidine ring, which is a six-membered ring containing one nitrogen atom. The presence of two methyl groups at the 2 and 6 positions introduces steric factors that can significantly affect the compound's reactivity.
  • Nitroso Group Influence: The nitroso group (–NO) attached to the piperidine is a crucial aspect. It plays a vital role in various chemical reactions, such as nucleophilic substitutions and aromatic coupling reactions, making this compound valuable in synthetic organic chemistry.
  • Biological Activities: Compounds featuring a nitroso group have been studied for their potential biological activities. Research indicates that 2,6-dimethyl-1-nitroso-piperidine may exhibit antimicrobial or antitumor properties, making it a candidate for further pharmacological exploration.
  • Applications in Synthesis: This compound can serve as an intermediate in the synthesis of more complex organic molecules. Its unique architecture allows for the development of new compounds with enhanced properties.
  • Safety Considerations: As with many nitroso compounds, handling and disposal should be approached with caution. Proper laboratory protocols must be observed to mitigate potential hazards associated with its reactivity.

In summary, 2,6-dimethyl-1-nitroso-piperidine is a compound that encapsulates the essence of organic synthesis and medicinal chemistry. Its intriguing structural nuances and potential applications make it a notable subject of study for chemists and students alike.

Synonyms
2,6-Dimethyl-1-nitrosopiperidine
N-Nitroso-2,6-dimethylpiperidine
2,6Dimethylnitrosopiperidine
2,6DimethylNnitrosopiperidine
2,6Dimethyl1nitrosopiperidine
Piperidine, 2,6dimethyl1nitroso
877-192-5
17721-95-8
nitroso-2,6-dimethylpiperidine
2,6-Dimethyl-N-nitrosopiperidine
2,6-Dimethylnitrosopiperidine
PIPERIDINE, 2,6-DIMETHYL-1-NITROSO-
BRN 0114715
5-20-04-00188 (Beilstein Handbook Reference)
CHEMBL349863
SCHEMBL8944270
DTXSID00875699
MDOIIQGEWWYGKD-UHFFFAOYSA-N
3W4UV8346D
2,6-Dimethyl-1-nitrosopiperidine #
EN300-21626292