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2,6-Lutidine

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Identification
Molecular formula
C7H9N
CAS number
108-48-5
IUPAC name
2,6-dimethylpyridine
State
State

At room temperature, 2,6-Lutidine is in a liquid state. It is also highly flammable, so it should be handled with caution, particularly near heat sources or open flames.

Melting point (Celsius)
-6.00
Melting point (Kelvin)
267.15
Boiling point (Celsius)
144.00
Boiling point (Kelvin)
417.15
General information
Molecular weight
107.16g/mol
Molar mass
107.1620g/mol
Density
0.9227g/cm3
Appearence

2,6-Lutidine is a colorless, clear liquid with a characteristic pungent odor. Due to its distinct smell, it is easily recognizable, and care should be taken to minimize exposure.

Comment on solubility

Solubility of 2,6-dimethylpyridine

2,6-dimethylpyridine, with the chemical formula C8H9N, is an organic compound known for its intriguing solubility characteristics. This compound is quite versatile when it comes to solubility in various solvents:

  • Water: 2,6-dimethylpyridine exhibits limited solubility in water due to its organic nature and the presence of a non-polar hydrocarbon chain.
  • Organic Solvents: It is soluble in a range of organic solvents, including alcohols, ethers, and other polar aprotic solvents.
  • Polarity Influence: The solubility of 2,6-dimethylpyridine is significantly affected by the polarity of the solvent; it prefers polar aprotic or slightly polar solvents for enhanced solubility.

To summarize, while 2,6-dimethylpyridine holds a place in various non-aqueous environments through its solubility in organic solvents, its limited water solubility makes it less applicable in aqueous-based chemical environments. This distinct solubility profile contributes to its utility in organic synthesis and as an industrial solvent.

Interesting facts

Interesting Facts about 2,6-Dimethylpyridine

2,6-Dimethylpyridine, as a member of the pyridine family, is an important aromatic heterocyclic compound. Here are some engaging facts about this intriguing chemical:

  • Structural Characteristics: This compound features a pyridine ring with two methyl groups attached at the 2 and 6 positions, which significantly affects its chemical properties and reactivity.
  • Industrial Use: Primarily, 2,6-dimethylpyridine is utilized as a solvent and intermediate in the synthesis of various agrochemicals, pharmaceuticals, and dyes, contributing to its importance in industrial chemistry.
  • Chemical Behavior: The presence of two methyl groups enhances the electron density on the nitrogen atom of the pyridine ring, which in turn influences its ability to act as a basic site in reactions.
  • Synthesis: It can be synthesized through several methods, including the methylation of pyridine or the alkylation of 2,6-lutidine, showcasing the versatility of organic synthesis techniques.
  • Applications in Research: Due to its unique chemical structure, 2,6-dimethylpyridine serves as a key reagent in the development of various chemical compounds. Its derivatives can exhibit antimicrobial and anti-inflammatory properties, making it a subject of interest in medicinal chemistry.
  • Aromaticity: Like its pyridine base, 2,6-dimethylpyridine displays significant aromatic character, impacting its stability and reactivity in various chemical environments.

In summary, 2,6-dimethylpyridine is not only pivotal for industrial applications but also serves as a fascinating example of how slight modifications in molecular structure can lead to diverse properties and uses. This makes it an interesting topic for both chemistry students and professionals alike!

Synonyms
2,6-Dimethylpyridine
2,6-LUTIDINE
108-48-5
Lutidine
Pyridine, 2,6-dimethyl-
2,6-Dimethypyridine
alpha,alpha'-Lutidine
2,6-dimethyl-pyridine
alpha,alpha'-Dimethylpyridine
FEMA No. 3540
2,6-Lutidene
HSDB 79
NSC 2155
EINECS 203-587-3
UNII-15FQ5D0T3P
MFCD00006345
15FQ5D0T3P
2,6-Litidine-d6
DTXSID7051557
CHEBI:32548
AI3-24282
.alpha.,.alpha.'-Dimethylpyridine
NSC-2155
2,6-Lutidine, 8CI
.alpha.,.alpha.'-Lutidine
2,6-LUTIDINE [MI]
2,6-LUTIDINE [HSDB]
DTXCID1030109
DIMETHYLPYRIDINE, 2,6-
FEMA 3540
2,6-DIMETHYLPYRIDINE [FHFI]
2,6-DIMETHYLPYRIDINE-D9
LUT
alpha,alpha'-Lutidin
lutidin
2,6-Lutidine (8CI); 2,6-Dimethylpyridine; NSC 2155; a,a'-Dimethylpyridine; a,a'-Lutidine
a,Alpha'-lutidine
2,6Lutidine
2,6 lutidine
2-6-lutidine
2.6-lutidine
2,6dimethylpyridine
alpha,alpha'Lutidine
2,6 -lutidine
2,6- lutidine
LUTIDENE
2,6-dimethylpiridine
2.6-dimethylpyridine
2,6-dimethyl pyridin
2,6-dimethyl pyridine
Pyridine, 2,6dimethyl
a,Alpha'-dimethylpyridine
alpha,alpha'Dimethylpyridine
.alpha.,.alpha.'-Lutidin
2,6-Lutidine, redistilled
SCHEMBL9611
CHEMBL22976
2,6-Dimethylpyridine, >=99%
NSC2155
2,6-Dimethylpyridine, redistilled
2,6-Lutidine, analytical standard
Tox21_303862
BBL013176
STL163956
AKOS005716680
AC-5116
FL15912
2,6-Lutidine, ReagentPlus(R), 98%
NCGC00357127-01
BP-30085
BP-31131
CAS-108-48-5
DB-013994
L0067
NS00010862
EN300-19113
F91703
2,6-Lutidine, purified by redistillation, >=99%
A801883
AC-907/25014177
Q209284
F0001-0171
Z104472820
Capping B2 (60 % lutidine in acetonitrile, for AKTA oligopilottrade mark) NC-0807, GL45 thread emp Biotech GmbH