Interesting facts
Interesting Facts about 2,6-Di-t-butyl-4-[1-(3,5-di-t-butyl-4-hydroxy-phenyl)sulfanyl-1-methyl-ethyl]sulfanyl-phenol
This compound, often known for its complex structure, is a fascinating example of how substituents can transform the reactivity and properties of a molecule. Here are some key points about it:
- Antioxidant Properties: The presence of the hydroxy group and bulky t-butyl substituents allow this compound to function effectively as an antioxidant, protecting other compounds from oxidative degradation.
- Thermal Stability: It is often used in plastics and rubber formulations due to its ability to resist thermal degradation, making materials more durable.
- Biological Impact: The sulfanyl groups present in the structure can enhance biological interactions, which is intriguing for studies in medicinal chemistry.
- Synthesis Challenges: Due to the intricate nature of its structure, synthesizing this compound can present challenges in terms of achieving regioselectivity and managing steric hindrance during reactions.
- Usage in Research: Researchers explore this compound in the realm of polymer science and material engineering, where its stabilizing properties can be crucial for developing new products.
As a student of chemistry, one can appreciate the beauty in how such a complex structure serves real-world applications. This compound exemplifies the balance between structure and function, highlighting the importance of molecular design in modern chemistry. Indeed, we can say, *“Great things are not done by impulse, but by a series of small things brought together.”* Such is the case with compounds like this, integral to the advancement of chemical science.
Synonyms
probucol
23288-49-5
Lorelco
Bisphenabid
Biphenabid
Bisbid
Lesterol
Lurselle
Lursell
DH-581
Panavir
Probucolum
Sinlestal
Probucolum [INN-Latin]
DH 581
Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole
4,4'-(Isopropylidenedithio)bis(2,6-di-tert-butylphenol)
NSC 86225
CCRIS 7510
Serterol
2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenol
NSC 652160
4,4'-(propane-2,2-diylbis(sulfanediyl))bis(2,6-di-tert-butylphenol)
Acetone, bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole
UNII-P3CTH044XJ
EINECS 245-560-9
P3CTH044XJ
NSC-86225
Phenol, 4,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-
NSC-652160
BRN 2026253
Probucol (Standard)
CHEBI:8427
2,6-di-tert-butyl-4-({2-[(3,5-di-tert-butyl-4-hydroxyphenyl)sulfanyl]propan-2-yl}sulfanyl)phenol
DTXSID2045440
MFCD00079281
CHEMBL608
4,4'-(propane-2,2-diyldisulfanediyl)bis(2,6-di-tert-butylphenol)
MLS000028492
DTXCID0025440
NSC86225
Phenol, 4,4'-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl)-
NSC652160
Probucol [USAN:USP:INN:BAN:JAN]
4,4'-(Isopropylidenedithio)bis(2, 6-di-tert-butylphenol)
4,4'-(Isopropylidenedithio)bis[2, 6-di-tert-butylphenol]
NCGC00016777-01
SMR000058265
Superlipid
Probucolum (INN-Latin)
CAS-23288-49-5
PROBUCOL (MART.)
PROBUCOL [MART.]
PROBUCOL (USP-RS)
PROBUCOL [USP-RS]
PROBUCOL (USP IMPURITY)
PROBUCOL [USP IMPURITY]
4,4'- (Isopropylidenedithio)bis(2,6-di-tert-butylphenol)
Probucol (USAN:USP:INN:BAN:JAN)
DH581
SR-01000695447
LORELCO (TN)
probucolo
Probucol,(S)
Prestwick_408
DE-3872
Spectrum_001296
Acetone, bis (3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole
PROBUCOL [USAN]
PROBUCOL [INN]
PROBUCOL [JAN]
PROBUCOL [MI]
PROBUCOL [VANDF]
Opera_ID_1820
Prestwick0_000384
Prestwick1_000384
Prestwick2_000384
Prestwick3_000384
Spectrum2_001400
Spectrum3_001438
Spectrum4_000414
Spectrum5_001343
PROBUCOL [WHO-DD]
Phenol, 4,4'-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl))-
SCHEMBL4150
BSPBio_000567
BSPBio_003176
KBioGR_000708
KBioGR_002394
KBioSS_001776
KBioSS_002399
Probucol, analytical standard
DivK1c_000599
SPECTRUM1501109
Probucol (JP17/USP/INN)
SPBio_001420
SPBio_002488
PROBUCOL [ORANGE BOOK]
BPBio1_000625
GTPL7277
HMS501N21
HY-B0388R
KBio1_000599
KBio2_001776
KBio2_002394
KBio2_004344
KBio2_004962
KBio2_006912
KBio2_007530
KBio3_002396
KBio3_002873
C10AX02
cMAP_000039
NINDS_000599
4,4'- (Isopropylidenedithio)bis(2, 6-di-tert-butylphenol)
GLXC-10304
HMS1569M09
HMS1921D21
HMS2092D05
HMS2096M09
HMS2233C08
HMS3655P19
HMS3713M09
Pharmakon1600-01501109
BCP06487
HY-B0388
Tox21_110605
BDBM50007260
CCG-38986
NSC757837
s2119
STK762566
AKOS001740866
Tox21_110605_1
DB01599
FP27164
KS-1459
NSC-757837
2,6-bis(tert-butyl)-4-{1-[3,5-bis(tert-butyl)-4-hydroxyphenylthio]-isopropylth io}phenol
IDI1_000599
NCGC00016777-02
NCGC00016777-03
NCGC00016777-04
NCGC00016777-05
NCGC00016777-06
NCGC00016777-07
NCGC00016777-08
NCGC00094895-01
NCGC00094895-02
NCGC00094895-03
NCGC00094895-04
AC-31457
SBI-0051640.P002
DB-046120
AB00052202
CS-0694884
NS00003652
P2002
SW196648-3
C07373
D00476
EN300-122630
F20384
AB00052202_14
AB00052202_15
Acetone,5-di-tert-butyl-4-hydroxyphenyl) mercaptole
SR-01000695447-2
SR-01000695447-3
BRD-K72029282-001-04-8
BRD-K72029282-001-15-4
BRD-K72029282-001-22-0
BRD-K72029282-001-23-8
Q10354103
Acetone bis(3,5-di-t-butyl-4-hydroxyphenyl) mercaptole
Z1544404498
Bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptole acetone
Probucol, United States Pharmacopeia (USP) Reference Standard
Phenol,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-
2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol
4,4'-(Propan-2,2-diylbis(sulfandiyl))bis(2,6-bis(1,1-dimethylethyl)phenol)
2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol
2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol)
2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol
2,6-Ditert-butyl-4-((1-[(3,5-ditert-butyl-4-hydroxyphenyl)sulfanyl]-1-methylethyl)sulfanyl)phenol #
2,6-ditert-butyl-4-[1-(3,5-ditert-butyl-4-hydroxy-phenyl)sulfanyl-1-methyl-ethyl]sulfanyl-phenol
245-560-9
Solubility of 2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenyl)sulfanyl-1-methyl-ethyl]sulfanyl-phenol
The solubility of 2,6-di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenyl)sulfanyl-1-methyl-ethyl]sulfanyl-phenol (C73H108O12) is quite intriguing due to its complex structure and extensive hydrophobic regions. This compound is expected to exhibit limited solubility in aqueous solutions, as indicated by several key factors:
As a rule of thumb in chemistry, “like dissolves like”, meaning that the solubility of polar substances is favored in polar solvents and non-polar substances in non-polar solvents. Consequently, the overall solubility of this compound is anticipated to be low in polar solvents like water but may be higher in organic solvents such as chloroform or toluene.