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2,6,8-Trichloropurine

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Identification
Molecular formula
C5HCl3N4
CAS number
2538-55-4
IUPAC name
2,6,8-trichloro-1H-purine
State
State

At room temperature, 2,6,8-Trichloropurine is typically found in a solid state. It maintains its crystalline integrity unless subjected to temperatures approaching its melting point.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
368.00
Boiling point (Kelvin)
641.15
General information
Molecular weight
222.46g/mol
Molar mass
222.4560g/mol
Density
1.9870g/cm3
Appearence

The compound appears as a whitish to light brown powder or crystalline solid. It is typically characterized by the presence of three chlorine atoms which might influence its hue under certain conditions. The solid nature of this chemical is consistent with other chlorinated purines, which often form well-defined crystalline structures.

Comment on solubility

Solubility of 2,6,8-Trichloro-1H-purine

When examining the solubility of 2,6,8-trichloro-1H-purine, it is essential to consider the influence of its chemical structure on its interaction with solvents. This compound features three chlorine atoms, which significantly affect its solubility properties.

Key Factors Influencing Solubility:

  • Polarity: The presence of chlorine atoms increases the polarity of the molecule, which may enhance the solubility in polar solvents.
  • Hydrogen Bonding: Although 1H-purines can form hydrogen bonds, the substitution of chlorine atoms can hinder this process, impacting solubility.
  • Solvent Choice: Commonly, 2,6,8-trichloro-1H-purine exhibits limited solubility in non-polar solvents but can be more soluble in polar aprotic solvents like dimethyl sulfoxide (DMSO) or acetonitrile.

Overall, while predictions can be drawn from structural considerations, experimental data is fundamental to ascertain precise solubility. The interaction between solvent and solute is critical, underlining that solubility could vary based on factors like temperature and concentration.

In conclusion, if you're working with 2,6,8-trichloro-1H-purine, take into account these factors for optimal use in your chemical applications!

Interesting facts

Interesting Facts about 2,6,8-Trichloro-1H-Purine

2,6,8-Trichloro-1H-purine is an intriguing chemical compound that belongs to the purine class, which is essential for various biological functions. This compound is particularly notable due to its structural variations, which can lead to diverse properties and applications. Here are some interesting aspects:

  • Biological Importance: Purines, in general, play a critical role in the formation of nucleotides, the building blocks of DNA and RNA. This means that compounds like 2,6,8-trichloro-1H-purine could have significant implications for genetic research and biotechnology.
  • Antiviral Potential: Research has indicated that certain derivatives of purines exhibit antiviral properties. Scientists are exploring these types of compounds for their potential use in pharmaceutical developments aimed at combating viral infections.
  • Synthesis: The synthesis of chlorinated purines showcases the versatility and creativity of organic chemistry. It often involves a range of techniques, from electrophilic substitution reactions to more complex strategies that target specific sites in the purine ring structure.
  • Research Interest: Ongoing studies into the effects of chlorinated purines on biological systems provide insights into how such compounds interact at a molecular level. These insights can further our understanding of nucleic acid metabolism and its regulatory mechanisms.

Overall, 2,6,8-trichloro-1H-purine serves as a fascinating topic in the field of chemistry, blending elements of organic synthesis, molecular biology, and medicinal chemistry. As we continue to investigate its properties and potential applications, the significance of this compound in scientific research may become even more pronounced.