Interesting facts
Interesting Facts about [2,8-bis(trifluoromethyl)-4-quinolyl]-(2-piperidyl)methanol
This intriguing compound, known for its complex structure and unique properties, falls under the category of fluorinated quinolines. Here are some noteworthy aspects:
- Fluorination Advantage: The presence of trifluoromethyl groups enhances the compound’s lipophilicity, which can significantly affect its bioavailability and interactions in biological systems.
- Quinoline Derivative: As a quinoline derivative, this compound may exhibit interesting pharmaceutical properties. Quinolines are often known for their pharmacological activities, including antimalarial, antibacterial, and anticancer effects.
- Potential Applications: Researchers are exploring such compounds for their viability in drug development. The unique structural features can lead to the discovery of novel therapeutic agents targeting specific diseases.
- Analytical Studies: This compound can serve as a valuable model for studies involving organofluorine chemistry, which is pivotal in both medicinal and materials chemistry.
- Research Interest: There is a growing interest in compounds featuring fluorinated groups due to their stability and ability to influence the electronic properties of molecules.
As chemists continue to investigate the properties and reactions of compounds like [2,8-bis(trifluoromethyl)-4-quinolyl]-(2-piperidyl)methanol, it becomes evident that the world of chemical compounds holds infinite possibilities for innovation and discovery.
Synonyms
mefloquine
Lariam
49752-90-1
GNF-Pf-5544
[2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol
[2,8-bis(trifluoromethyl)quinolin-4-yl](piperidin-2-yl)methanol
alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol
CHEMBL416956
alpha-2-Piperidyl-2,8-bis(trifluoromethyl)quinoline-4-methanol
CHEBI:63681
Racemic mefloquine
(2,8-bis(trifluoromethyl)quinolin-4-yl)(piperidin-2-yl)methanol
[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol
Mefloquinone
WR-142490
melfoquine
Mefaquin
rac-mefloquine
SR-05000001820
threo-MefloquineHydrochloride
NSC-758233
EINECS 256-468-3
WR 142,490
Spectrum_001312
Prestwick0_000126
Prestwick1_000126
Prestwick2_000126
Prestwick3_000126
Spectrum2_001516
Spectrum3_000953
Spectrum4_001066
Spectrum5_001122
SCHEMBL21782
BSPBio_000172
KBioGR_001392
KBioSS_001792
DivK1c_000790
SPECTRUM1503070
SPBio_001591
SPBio_002111
BPBio1_000190
GTPL4252
[(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol
HMS502H12
KBio1_000790
KBio2_001792
KBio2_004360
KBio2_006928
KBio3_002046
DTXSID50860636
(DL-erythro-.alpha.-2-Piperidyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol
NINDS_000790
HMS1922C09
4-Quinolinemethanol, .alpha.-(2R)-2-piperidinyl-2,8-bis(trifluoromethyl)-, (.alpha.S)-rel-
BCP09262
BDBM50022889
CCG-39182
STL581681
AKOS030575625
DB00358
IDI1_000790
NCGC00094994-01
NCGC00094994-02
NCGC00094994-03
NCGC00094994-04
NCGC00094994-06
SBI-0051761.P002
DB-179095
AB00052310
NS00005035
Ro-21-5998-001
AB00052310_09
EN300-1696285
Q736270
BRD-A89585551-003-03-4
BRD-A89585551-003-08-3
BRD-A89585551-003-16-6
SR-05000001820-11
(2,8-Bis-trifluoromethyl-quinolin-4-yl)-piperidin-2-yl-methanol
4-Quinolinemethanol, alpha-2-piperidinyl-2,8-bis(trifluoromethyl)-
rel-(2,8-bis(trifluoromethyl)quinolin-4-yl)(piperidin-2-yl)methanol
(2,8-Bis-trifluoromethyl-quinolin-4-yl)-(1-methyl-piperidin-2-yl)-methanol
(S)-(2,8-Bis-trifluoromethyl-quinolin-4-yl)-(R)-piperidin-2-yl-methanol
(S)-(2,8-Bis-trifluoromethyl-quinolin-4-yl)-piperidin-2-yl-methanol
2-[(2,8-Bis-trifluoromethyl-quinolin-4-yl)-hydroxy-methyl]-piperidinium
(2,8-Bis-trifluoromethyl-quinolin-4-yl)-piperidin-2-yl-methanol( Mefloquine)
(2,8-Bis-trifluoromethyl-quinolin-4-yl)-piperidin-2-yl-methanol; (Mefloquine or MF)
2,8-di(trifluoromethyl)-4-quinolyl-hexahydro-2-pyridinylmethanol(Mefloquine)
4-Quinolinemethanol, .alpha.-2-piperidinyl-2,8-bis(trifluoromethyl)-, (R*,S*)-(.+/-.)-
Solubility of [2,8-bis(trifluoromethyl)-4-quinolyl]-(2-piperidyl)methanol
The solubility of the compound [2,8-bis(trifluoromethyl)-4-quinolyl]-(2-piperidyl)methanol (C19H18F6N2O) can exhibit unique characteristics due to its chemical structure.
Factors Influencing Solubility:
In conclusion, the overall solubility of this compound will depend largely on the balance between the hydrophilic (water-attracting) and lipophilic (fat-attracting) parts of its structure. Experimental determination is essential to ascertain its behavior in various solvents.