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2,8-Dimethylquinoline

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Identification
Molecular formula
C11H11N
CAS number
2931-97-9
IUPAC name
2,8-dimethylquinoline
State
State

At room temperature, 2,8-Dimethylquinoline is in a liquid state. It is typically a colorless to pale yellow liquid, which can slowly darken upon exposure to light and air.

Melting point (Celsius)
16.00
Melting point (Kelvin)
289.00
Boiling point (Celsius)
262.00
Boiling point (Kelvin)
535.00
General information
Molecular weight
157.22g/mol
Molar mass
157.2210g/mol
Density
1.0164g/cm3
Appearence

2,8-Dimethylquinoline typically appears as a colorless to pale yellow liquid. Its appearance might vary slightly due to impurities, but it generally maintains a clear liquid form under standard conditions.

Comment on solubility

Solubility of 2,8-Dimethylquinoline

2,8-Dimethylquinoline, a derivative of quinoline, presents some interesting characteristics regarding its solubility. The solubility of a compound like 2,8-dimethylquinoline can be influenced by several factors, including:

  • Polarity: Quinoline derivatives typically exhibit moderate polarity, which can affect their solubility in polar vs. non-polar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding can enhance solubility in certain solvents, particularly those that can participate in hydrogen bonding interactions.
  • Temperature: The solubility of many organic compounds, including 2,8-dimethylquinoline, generally increases with temperature.

In practice, 2,8-dimethylquinoline is expected to be soluble in organic solvents such as ethanol, methanol, and chloroform, while showing limited solubility in water due to its aromatic structure. This is consistent with the behavior of many aromatic nitrogen-containing compounds, which tend to favor organic solvent interactions.

As stated, "Like dissolves like." Thus, for 2,8-dimethylquinoline, its solubility characteristics make it more compatible with non-polar or weakly polar solvents rather than highly polar environments. Understanding the solubility behavior is crucial for applications in organic synthesis and medicinal chemistry.

Interesting facts

Interesting Facts About 2,8-Dimethylquinoline

2,8-Dimethylquinoline is a fascinating heterocyclic compound that belongs to the quinoline family. Its unique structure and properties make it an interesting subject of study in various fields of chemistry, including organic synthesis and medicinal chemistry.

Key Characteristics

  • Quinoline Derivative: 2,8-Dimethylquinoline is a derivative of quinoline, which consists of a fused benzene and pyridine ring. This structure contributes to its distinct chemical behavior.
  • Hypoxic Response: Research suggests that 2,8-Dimethylquinoline can exhibit a hypoxic response, making it useful in studies related to oxygen deprivation in biological systems.
  • Fluorescent Properties: The compound has demonstrated fluorescence under specific conditions, which opens avenues for its application in fluorescence microscopy and biochemical assays.

Applications and Implications

  • Pharmaceutical Development: Due to its potential biological activity, 2,8-Dimethylquinoline is being investigated as a lead compound in drug discovery, particularly in the synthesis of new antimicrobial and anti-cancer agents.
  • Dyes and Pigments: The unique properties of this compound make it useful in the formulation of dyes and pigments, contributing to the vibrant colors in various materials.
  • Ligands in Coordination Chemistry: 2,8-Dimethylquinoline can act as a ligand in coordination complexes, showing promising interactions with metal ions, which could lead to novel catalysts.

Quote from the Literature

As one study highlights, “The intriguing interactions of 2,8-Dimethylquinoline with biological macromolecules illustrate its potential for therapeutic applications and broaden our understanding of quinoline derivatives in medicinal chemistry.” This statement encapsulates the compound's significance in ongoing research.

Overall, 2,8-Dimethylquinoline represents a vibrant intersection of organic chemistry and practical applications, making it a compound of high interest for chemists and researchers alike.

Synonyms
2,8-DIMETHYLQUINOLINE
1463-17-8
Quinoline, 2,8-dimethyl-
UNII-3693PC4G7D
O-TOLUQUINALDINE
3693PC4G7D
8-METHYLQUINALDINE
EINECS 215-974-4
NSC-62133
QUINOLINE, 2,8-DIMETHYL
DTXSID80163349
NSC 62133
DTXCID8085840
215-974-4
belfsavwjlqibb-uhfffaoysa-n
MFCD00010091
NSC62133
SCHEMBL806441
2 pound not8-Dimethylquinoline
2,8-DIMETHYL-QUINOLINE
BCP23522
AKOS006282040
AB01019
CS-W021532
DS-5130
SY041606
DB-020269
NS00024789
F12427
AO-801/41077419
Q27256544