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Forskolin

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Identification
Molecular formula
C22H34O7
CAS number
66575-29-9
IUPAC name
2,8,16-trihydroxy-9-(hydroxymethyl)-5,5-dimethyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecan-15-one
State
State

At room temperature, forskolin is a crystalline solid.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
381.79
Boiling point (Kelvin)
654.94
General information
Molecular weight
410.51g/mol
Molar mass
410.4900g/mol
Density
1.3002g/cm3
Appearence

The compound typically appears as an off-white to pale yellow coloured crystalline powder. It is sensitive to light and moisture, necessitating storage in a cool, dark place.

Comment on solubility

Solubility of 2,8,16-Trihydroxy-9-(hydroxymethyl)-5,5-dimethyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecan-15-one

The solubility of the compound C22H34O7 can be considered through various factors that influence the behavior of organic molecules in different solvents. Understanding its solubility is crucial for applications in pharmaceuticals, chemical synthesis, and material science.


Factors Influencing Solubility

  • Molecular Structure: The presence of multiple hydroxyl groups (–OH) in this compound enhances its interaction with polar solvents like water.
  • Hydrophobic Regions: Meanwhile, the tetracyclic structure introduces hydrophobic characteristics that may limit its solubility in such polar mediums.
  • Temperature: Higher temperatures often increase solubility, particularly for organic compounds, altering balance between polar and non-polar interactions.

Solvent Interaction

This compound is likely to exhibit the following solubility behavior:

  • Highly soluble: In polar solvents due to its hydroxyl groups.
  • Moderately soluble: In less polar organic solvents, where some polar interactions still aid solubility.
  • Poorly soluble: In non-polar solvents, as a result of the extensive hydrophobic character provided by its tetracyclic framework.

In summary, the interplay between hydrophilic (hydroxyl groups) and hydrophobic features (tetracyclic structure) dictates the solubility of this intriguing compound, making it crucial to choose the right solvent for effective applications. Understanding these solubility properties not only facilitates better utilization but also aids in predicting behavior in various environments.

Interesting facts

Interesting Facts About 2,8,16-Trihydroxy-9-(hydroxymethyl)-5,5-dimethyl-14-methylene-tetracyclo[11.2.1.01,10.04,9]hexadecan-15-one

This complex organic compound belonging to the class of tetracyclic structures exhibits fascinating features that make it a topic of interest in the field of chemistry. Here are some engaging points about this intriguing molecule:

  • Structural Complexity: The compound possesses a unique tetracyclic system, which means it contains four interconnected rings. This structural architecture contributes to its chemical reactivity and potential biological activity.
  • Hydroxyl Groups: With multiple hydroxyl groups (−OH) present, this compound is likely to demonstrate properties such as solubility in water and reactivity with various organic compounds, making it an interesting subject for synthetic and medicinal chemistry.
  • Natural Sources: Compounds with similar structural motifs are often found in nature. They frequently exhibit bioactivity, which makes them of interest for studies on natural products and potential pharmaceutical applications.
  • Potential Applications: The presence of hydroxymethyl and methylene groups may suggest that this compound could be investigated for its use in drug design or as a precursor in the synthesis of more complex molecules within medicinal chemistry.

As a chemistry student or scientist, understanding the synthesis, properties, and potential applications of such compounds can lead to exciting discoveries in both academic research and practical applications. Engaging with such complex molecules not only enhances our understanding of organic chemistry but opens doors to innovative solutions in various fields, including pharmacology and materials science.

"Chemistry is the central science," and compounds like this exemplify its beauty and intricacies. Continuous exploration of such compounds empowers scientists to unveil the mysteries locked within their structures, paving the way for groundbreaking advancements.

Synonyms
kamebakaurin
2,8,16-Trihydroxy-9-(hydroxymethyl)-5,5-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one
1,7,14,20-Tetrahydroxykaur-16-en-15-one (1alpha,7alpha,14R)
YCA98134
AKOS037514711
2,8,16-trihydroxy-9-(hydroxymethyl)-5,5-dimethyl-14-methylidenetetracyclo[11.2.1.0(1),(1)?.0?,?]hexadecan-15-one