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Quinine

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Identification
Molecular formula
C20H24N2O2
CAS number
130-95-0
IUPAC name
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one;(R)-(6-methoxy-4-quinolyl)-[(2S,4R,5R)-5-vinylquinuclidin-2-yl]methanol
State
State

Quinine is typically found in a solid state at room temperature, often in the form of a crystalline substance.

Melting point (Celsius)
177.00
Melting point (Kelvin)
450.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
324.43g/mol
Molar mass
324.4330g/mol
Density
1.2500g/cm3
Appearence

Quinine typically appears as a white crystalline alkaloid. It can also take the form of a fine white powder. It is odorless and has an intensely bitter taste.

Comment on solubility

Solubility of (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one and (R)-(6-methoxy-4-quinolyl)-[(2S,4R,5R)-5-vinylquinuclidin-2-yl]methanol

When examining the solubility of complex organic compounds such as (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one and (R)-(6-methoxy-4-quinolyl)-[(2S,4R,5R)-5-vinylquinuclidin-2-yl]methanol, several factors come into play that determine their ability to dissolve in various solvents.

Key Factors Influencing Solubility:

  • Polarity: Generally, polar compounds tend to dissolve well in polar solvents, while non-polar compounds are better suited for non-polar solvents.
  • Hydroxyl Groups: The presence of hydroxyl (-OH) groups, as seen in the first compound, typically enhances solubility in water due to hydrogen bonding.
  • Molecular Structure: The intricate molecular configurations can hinder or facilitate interaction with solvents.
  • Temperature: Higher temperatures often increase the solubility of solids in liquids.

For these specific compounds:

  • (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one is likely to exhibit good solubility in polar solvents like water and ethanol due to its multiple -OH groups.
  • (R)-(6-methoxy-4-quinolyl)-[(2S,4R,5R)-5-vinylquinuclidin-2-yl]methanol, on the other hand, may present limited solubility in water but could be more soluble in organic solvents owing to its larger aromatic structure.

In summary, the solubility of these compounds will vary significantly depending on the solvent environment and their unique structural characteristics. As the saying goes, "like dissolves like," and understanding these nuances can lead to better predictions and applications in chemical processes.

Interesting facts

Interesting Facts about the Compound

The compound known as (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxy-furan-3-one; (R)-(6-methoxy-4-quinolyl)-[(2S,4R,5R)-5-vinylquinuclidin-2-yl]methanol is a fascinating subject in the world of chemistry. Here are some noteworthy points:

  • Structural Complexity: This compound features a unique dual structure that incorporates furan and quinoline moieties, showcasing a rich tapestry of functional groups. Such complexity often leads to intriguing chemical behavior.
  • Biological Significance: Compounds of this nature are of considerable interest in pharmaceutical research due to their potential biological activities. The presence of multiple hydroxyl groups typically enhances solubility and bioactivity.
  • Versatile Applications: The distinctive features of this compound may lend themselves to various applications, including medicinal chemistry, where researchers explore its potential as a therapeutic agent.
  • Synthesis Challenges: Due to its intricate structure, synthesizing this compound can present significant challenges. It often requires advanced techniques and strategic planning in synthetic methodologies.
  • Historical Context: Compounds such as this one have been studied for many years, often being highlighted in academic journals for their intriguing properties and applications in drug development.

In summary, this compound exemplifies the beauty and complexity of organic chemistry. Its multifunctional groups suggest promising avenues for research, and it continues to captivate scientists and students alike. As we delve deeper into the mechanisms of action and explore future applications, the potential of this compound remains vast and largely untapped.