2-(2,6-dimethylphenoxy)cyclopropanamine

Identification

Molecular formula

C₁₂H₁₇NO

CAS number

773855-64-4

IUPAC name

(2R)-2-(2,6-dimethylphenoxy)cyclopropanamine

State

Under standard conditions of temperature and pressure, this compound is typically a liquid. It may exist as a solid if cooled sufficiently below room temperature.

Melting point (Celsius)

32.30

Melting point (Kelvin)

305.50

Boiling point (Celsius)

272.50

Boiling point (Kelvin)

545.60

General information

Molecular weight

177.26g/mol

Molar mass

177.2600g/mol

Density

0.9290g/cm³

Appearence

The compound is typically a clear, colorless to pale yellow liquid. It may also be found as a solid at lower temperatures, depending on its specific form and purity.

Comment on solubility

Solubility of (2R)-2-(2,6-dimethylphenoxy)cyclopropanamine

The solubility of (2R)-2-(2,6-dimethylphenoxy)cyclopropanamine is influenced by its chemical structure and functional groups. Here are several aspects to consider:

Polarity: The presence of the polar amine group enhances the solubility in polar solvents, such as water or alcohols.
Alkyl Groups: The bulky 2,6-dimethylphenoxy group may decrease solubility in more polar solvents due to steric hindrance.
Hydrogen Bonding: The potential for hydrogen bonding with water can lead to increased solubility compared to non-polar compounds.
Solvent Compatibility: This compound may be more soluble in organic solvents like ethyl acetate or chloroform due to its hydrophobic character.

In summary, while (2R)-2-(2,6-dimethylphenoxy)cyclopropanamine can display a degree of solubility in polar solvents, its overall solubility may be limited by its hydrophobic characteristics and steric factors. Understanding these nuances is crucial for applications in various chemical environments.

Interesting facts

Interesting Facts about (2R)-2-(2,6-dimethylphenoxy)cyclopropanamine

(2R)-2-(2,6-dimethylphenoxy)cyclopropanamine is an intriguing compound that belongs to a class of chemicals known as cyclic amines. Here are some noteworthy aspects:

Structural Characteristics: The compound features a cyclopropane ring, which is known for its unique reactivity due to its strained structure. This strain can lead to interesting chemical transformations.
Stereochemistry: The designation (2R) indicates a specific three-dimensional arrangement of the atoms in the molecule, which can significantly influence its biological activity. Stereochemistry is vital in pharmaceuticals, as different isomers can yield vastly different effects in biological systems.
Diverse Applications: Due to the presence of the amine and ether functional groups, this compound might exhibit potential activity in medicinal chemistry. Compounds containing phenoxy groups are often investigated for their role in drug development.
Biological Relevance: Research indicates that certain cyclic amines exhibit neuropharmacological properties, making compounds like (2R)-2-(2,6-dimethylphenoxy)cyclopropanamine of interest in the study of drugs that affect the central nervous system.
Reaction Mechanisms: The reactivity of the cyclopropane moiety can lead to various synthetic pathways, including ring-opening reactions, which chemists can exploit to create more complex scaffolds in the laboratory.

In summary, (2R)-2-(2,6-dimethylphenoxy)cyclopropanamine is a compelling example of how structural features influence both chemical behavior and potential applications in the field of medicinal chemistry. Its unique properties make it a subject of interest for both researchers and students alike.