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Thioridazine

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Identification
Molecular formula
C21H26ClN3S2
CAS number
130-61-0
IUPAC name
(2R,3R)-2,3-dihydroxybutanedioic acid;1-methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine
State
State

Thioridazine is typically encountered in its solid state at room temperature. It is generally provided as a powder for pharmaceutical formulations.

Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
354.70
Boiling point (Kelvin)
627.85
General information
Molecular weight
407.04g/mol
Molar mass
370.5400g/mol
Density
1.1800g/cm3
Appearence

Thioridazine is a white to yellowish, odorless crystalline solid. It may appear as a powder and is typically used in its hydrochloride form for pharmaceutical applications. When exposed to air and light, there might be some changes in color due to oxidation.

Comment on solubility

Solubility of (2R,3R)-2,3-dihydroxybutanedioic acid; 1-methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine

The solubility of the compound known as (2R,3R)-2,3-dihydroxybutanedioic acid; 1-methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine can be quite intriguing due to its complex structure. Understanding the solubility characteristics is essential in applications such as pharmaceuticals and chemical synthesis. Here are some key considerations:

  • Hydrophilicity vs. Hydrophobicity: The presence of hydroxyl groups (–OH) in (2R,3R)-2,3-dihydroxybutanedioic acid suggests a degree of hydrophilicity, which typically enhances solubility in water.
  • Functional Groups: The *amine* and *phenyl* groups can influence solubility. The interaction between the electronegative nitrogen atom in the amine and water molecules may promote solubility in polar solvents.
  • pH Sensitivity: The solubility may change with varying pH levels, especially given the acidic nature of the dihydroxybutanedioic acid, which may ionize in basic conditions.

In summary, while the compound may exhibit reasonable solubility in polar solvents, it is also important to consider factors such as temperature, pH, and specific solvent interactions that can further affect its solubility profile. It is often true that the more *functional groups* present, the more complicated the solubility behavior, making each compound unique.

Interesting facts

Interesting Facts About (2R,3R)-2,3-Dihydroxybutanedioic Acid; 1-Methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine

(2R,3R)-2,3-dihydroxybutanedioic acid, also known as L-tartaric acid, is a fascinating compound with a rich history and significant applications in various fields.

Applications and Uses

This compound plays a vital role in several industries:

  • Food Industry: Utilized as an acidulant and stabilizing agent in the production of various beverages and foods.
  • Pharmaceuticals: Its enantiomers are used in the formulation of medications, influencing drug efficacy.
  • Cosmetics: Employed in skincare formulations for its exfoliating properties.

Historical Significance

L-tartaric acid has historical significance; it was first isolated in the 19th century from the residue left in wine casks.

Biological Importance

In nature, this compound is found in significant amounts in tartar, a byproduct of winemaking, and is crucial to the biological processes of various organisms.

Unique Properties

The dual hydroxyl groups in its structure give this compound unique properties that can:

  • Facilitate complex formation with metals, making it useful in chelation chemistry.
  • Participate in asymmetric synthesis, a fundamental aspect in the production of chiral drugs.

Additionally, the combination of this compound with 1-methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine opens doors to exciting research directions in the fields of medicinal chemistry and pharmacology. As a researcher, the study of this compound serves as a reminder of the intricate relationship between molecular structure and function.

In summary, (2R,3R)-2,3-dihydroxybutanedioic acid and its derivatives stand out not just for their utility but also for the fascinating chemistry they embody. Embracing its significance could lead to exciting discoveries in both synthetic and natural chemistry domains.

Synonyms
THENALIDINE TARTRATE
2784-55-6
Thenophenopiperidine tartrate
Sandostene
SANDOSTEIN
SANDOSTEN
H581Q95SJA
EINECS 220-493-8
UNII-H581Q95SJA
Piperidine, 1-methyl-4-(N-2-thenylanilino)-, tartrate
THENALIDINE TARTRATE [MART.]
AS-716
THENALIDINE TARTRATE [WHO-DD]
Piperidine, 1-methyl-4-(N-2-thenylanilino)-, tartrate (1:1)
1-METHYL-4-AMINO-N-PHENYL-N-(2-THENYL)PIPERIDINE TARTRATE
THENALIDINE TARTRATE (MART.)
4-PIPERIDINAMINE, 1-METHYL-N-PHENYL-N-(2-THIENYLMETHYL)-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1)
220-493-8
(2R,3R)-2,3-dihydroxybutanedioic acid;1-methyl-N-phenyl-N-(thiophen-2-ylmethyl)piperidin-4-amine
16509-35-6
orb1739964
DTXSID90937038
JNZAGODMPIMPAM-LREBCSMRSA-N
Q27279662
2,3-Dihydroxybutanedioic acid--1-methyl-N-phenyl-N-[(thiophen-2-yl)methyl]piperidin-4-amine (1/1)