Skip to main content

Perampanel

ADVERTISEMENT
Identification
Molecular formula
C23H30ClNO2
CAS number
380917-97-5
IUPAC name
[(2R,3R,4S)-3-methyl-2-(4-phenylbuta-1,3-dienyl)piperidin-1-ium-4-yl] 2-methylpropanoate;chloride
State
State

At room temperature, perampanel chloride is a solid.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
341.20
Boiling point (Kelvin)
614.35
General information
Molecular weight
557.51g/mol
Molar mass
557.5130g/mol
Density
1.1540g/cm3
Appearence

Perampanel chloride typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [(2R,3R,4S)-3-methyl-2-(4-phenylbuta-1,3-dienyl)piperidin-1-ium-4-yl] 2-methylpropanoate;chloride

The solubility of the compound in question, [(2R,3R,4S)-3-methyl-2-(4-phenylbuta-1,3-dienyl)piperidin-1-ium-4-yl] 2-methylpropanoate;chloride, can be influenced by several factors, making it a fascinating topic of discussion. Here are key points to consider:

  • Polarity: Due to the presence of the piperidinium ion, which is positively charged, and the ester and aromatic groups, the compound exhibits a balance between hydrophilicity and lipophilicity.
  • Solvent Interaction: The solubility will vary significantly depending on the solvent in which the compound is dissolved. For example:
    • In polar solvents (e.g., water, methanol), the cationic piperidinium component may enhance solubility.
    • In organic solvents (e.g., ethanol, acetone), the presence of phenyl and other hydrocarbon structures can improve the solubility.
  • Temperature Effects: Solubility could increase with temperature, a common phenomenon for organic salts.

In conclusion, the **solubility behavior** of this compound is a complex interplay of structural features and environmental conditions. Empirical testing is recommended to ascertain precise solubility values under various conditions.


Interesting facts

Interesting Facts about [(2R,3R,4S)-3-methyl-2-(4-phenylbuta-1,3-dienyl)piperidin-1-ium-4-yl] 2-methylpropanoate;chloride

This intriguing compound belongs to a class of molecules known for their biological activity. Here are some noteworthy points:

  • Stereochemistry: The compound features several chiral centers and thus exists in different stereoisomeric forms. This aspect is crucial, as the configuration can greatly influence the biological activity and pharmacological properties of the compound.
  • Bioactivity: Compounds related to piperidine structures often demonstrate a range of biological effects, including potential roles in neurotransmitter modulation. The unique side chain in this compound may enhance its binding affinity to specific receptors, leading to novel therapeutic applications.
  • Applications in Medicine: The interplay of the piperidinium structure and the conjugated double bonds in the side chain hints at potential uses in the development of new drugs, particularly in treating neurological disorders or cancer.
  • Aromatic Interactions: The presence of a phenyl group adds hydrophobic characteristics, allowing for interesting interactions with biological membranes and proteins. This suggests that the compound could be a valuable tool for studying membrane dynamics.
  • Research Significance: Ongoing research into compounds of this kind is essential for the discovery of novel therapeutics and can also contribute to our understanding of complex chemical interactions in biological systems.

As a scientist or chemistry student, delving deeper into the structure and function of this compound can reveal new pathways for drug development and advancements in medicinal chemistry. It embodies the intricacies of molecular design, where minute changes in structure can yield significant variations in activity and efficacy.