2'-Deoxy-6-thioguanosine | Solubility of Things

Identification

Molecular formula

C₁₀H₁₃N₅O₃S

CAS number

3414-84-8

IUPAC name

(2R,3R,4S,5R)-2-(2-amino-6-sulfanyl-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

State

At room temperature, 2'-Deoxy-6-thioguanosine is generally a solid. It is stable under standard laboratory conditions but should be handled carefully to prevent degradation.

Melting point (Celsius)

241.00

Melting point (Kelvin)

514.00

Boiling point (Celsius)

300.00

Boiling point (Kelvin)

573.00

General information

Molecular weight

285.31g/mol

Molar mass

285.3230g/mol

Density

2.6800g/cm³

Appearence

The compound typically appears as a white to off-white powder or crystalline solid. Its exact appearance might slightly vary depending on the method of preparation and purity.

Comment on solubility

Solubility of (2R,3R,4S,5R)-2-(2-amino-6-sulfanyl-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Understanding the solubility of a compound is crucial in various fields, especially in pharmaceuticals and biochemistry. For the compound (2R,3R,4S,5R)-2-(2-amino-6-sulfanyl-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, solubility can be influenced by several factors:

Polarity: This compound has multiple polar functional groups, which generally increases solubility in polar solvents such as water.
Hydrogen bonding: The presence of hydroxymethyl and amino groups allows for strong hydrogen bonding, enhancing solubility in aqueous environments.
Molecular interactions: Its purine base structure may interact favorably in biological systems, aiding its dissolution in cellular environments.

Overall, it can be anticipated that this compound is likely to exhibit high solubility in polar solvents due to its structural characteristics, which facilitate interactions with water molecules. Solubility can significantly affect the compound's bioavailability and efficacy in biological systems, making these solubility properties particularly important.

Interesting facts

Exploring the Compound: (2R,3R,4S,5R)-2-(2-amino-6-sulfanyl-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

This compound is a fascinating example of a modified sugar nucleotide, richly embedded within the fabric of biochemistry. Often referred to in studies related to nucleic acid chemistry, this compound serves as an integral part of biological processes. Here are some intriguing aspects worth noting:

Nucleoside Derivative: As a nucleoside analogue, it exhibits roles similar to those of natural nucleotides, potentially influencing replication and transcription processes.
Biological Activity: Compounds like this one can interact with enzymatic pathways, functioning either as substrates or inhibitors, thereby paving the way for therapeutic applications.
Research Implications: Scientists are continually studying such derivatives for their potential roles in antiviral and anticancer strategies, offering hope in the development of new treatments.
Structural Complexity: The intricate stereochemistry (2R,3R,4S,5R) not only defines its biological activity but also exemplifies the diversity and precision required in molecular design.

In the words of a renowned chemist, "The beauty of chemistry lies in its ability to transform simple building blocks into complex functionalities." This compound underscores that very essence, reminding us of the incredible diversity found in molecular structures and their profound implications in life sciences.

As scientists delve deeper into understanding the behavior of this compound, it becomes clear that its role extends beyond mere recognition in textbooks; it may one day contribute notably to groundbreaking therapies and innovative scientific advances. The journey of studying such compounds is both a challenge and an adventure, where every discovery pushes the boundaries of our comprehension.