Interesting facts
Interesting Facts about (2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
This compound is a fascinating example of a complex structure that incorporates multiple functional groups and stereocenters, granting it unique properties and potential applications in medicinal chemistry. Here are some intriguing facts about this compound:
Structural Intricacies
- The presence of multiple stereogenic centers makes this compound a chiral molecule, meaning it can exist in different configurations that may exhibit varying biological activities.
- The inclusion of an imidazodiazepine moiety is notable; these structures are often found in several pharmaceutical agents, particularly those targeting the central nervous system.
Biological Significance
- Compounds with imidazole components often exhibit biological activities such as antiviral, antibacterial, and antifungal properties.
- Given its structural complexity, this compound could potentially serve as a lead structure for developing new therapeutic agents, especially in the treatment of neurological disorders.
Potential Applications
- Researchers are exploring similar imidazodiazepine derivatives as anxiolytics and sedatives, showcasing their possible application in the realm of mental health.
- The tetrahydrofuran ring contributes to solubility and bioavailability, important factors when considering drug formulation.
This compound exemplifies the intricate relationships between chemical structure and biological activity, underscoring the importance of detailed structural analysis in drug development. As science progresses, the exploration of such compounds may unlock new therapeutic avenues and improve existing treatments.
Synonyms
coformycin
11033-22-0
UNII-E49510ZL0H
(R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol
CHEBI:16213
E49510ZL0H
Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-
NSC-277817
(8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
(2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)oxolane-3,4-diol
NSC 277817
IMIDAZO(4,5-D)(1,3)DIAZEPIN-8-OL, 3,4,7,8-TETRAHYDRO-3-.BETA.-D-RIBOFURANOSYL-, (8R)-
(8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo(4,5-d)(1,3)diazepin-8-ol
(2R,3R,4S,5R)-2-((8R)-8-hydroxy-7,8-dihydro-4H-imidazo(4,5-d)(1,3)diazepin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol
(R)-3,4,7,8-Tetrahydro-3-b-D-ribofuranosylimidazo(4,5-D)(1,3)diazepin-8-ol
(R)-3,4,7,8-Tetrahydro-3-I2-D-ribofuranosylimidazo(4,5-D)(1,3)diazepin-8-ol
IMIDAZO(4,5-D)(1,3)DIAZEPIN-8-OL, 3,4,7,8-TETRAHYDRO-3-BETA-D-RIBOFURANOSYL-, (8R)-
CHEMBL284483
NSC277817
SCHEMBL442534
YOOVTUPUBVHMPG-LODYRLCVSA-N
BDBM50367032
AKOS040745679
DA-64416
HY-117260
CS-0064597
C01677
Q27098587
Imidazo[4,5-d][1,3]diazepin-8-ol, 3,4,7,8-tetrahydro-3-.beta.-D-ribofuranosyl-, (8R)
Imidazo[4,5-d][1,3]diazepin-8-ol,3,4,7,8-tetrahydro-3-b-D-ribofuranosyl-, (8R)-
(2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Solubility Overview
The compound (2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol presents interesting considerations regarding its solubility characteristics. Evaluating the solubility of this complex structure is essential for understanding its potential applications.
Factors Influencing Solubility
Solvent Compatibility
The solubility of this compound is expected to vary significantly between solvents. It may exhibit the following trends:
In conclusion, the solubility of (2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol showcases the intricate balance of chemical structure and solvent interactions, emphasizing the importance of *solvent selection* in any practical application.