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Nicotinamide adenine dinucleotide

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Identification
Molecular formula
C21H27N7O14P2
CAS number
53-84-9
IUPAC name
[(2R,3R,4S,5R)-5-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-(pyridine-3-carbonyloxymethyl)tetrahydrofuran-2-yl]methyl pyridine-3-carboxylate
State
State

At room temperature, NAD is in a solid state as a mono- or di-hydrate, often found in the form of a white, crystalline powder.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
126.00
Boiling point (Kelvin)
399.15
General information
Molecular weight
663.43g/mol
Molar mass
663.4250g/mol
Density
1.3000g/cm3
Appearence

Nicotinamide adenine dinucleotide (NAD) is typically a white, crystalline powder.

Comment on solubility

Solubility of [(2R,3R,4S,5R)-5-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-(pyridine-3-carbonyloxymethyl)tetrahydrofuran-2-yl]methyl pyridine-3-carboxylate

This compound, with a complex structure, reveals interesting characteristics regarding its solubility:

  • Polarity: The presence of multiple functional groups such as hydroxy (-OH) and carboxylate (-COO-) contributes to its overall polarity. Generally, polar compounds tend to be soluble in polar solvents like water.
  • Hydrogen Bonding: The hydroxy groups might facilitate hydrogen bonding with water molecules, enhancing solubility.
  • Organic Solvents: Due to the aromatic pyridine rings, this compound may display solubility in organic solvents like methanol or ethanol, which are more non-polar in nature.
  • Temperature Dependence: Like many chemical compounds, solubility may increase with temperature, indicating that higher temperatures could help dissolve this compound more effectively.

In conclusion, the solubility of this compound can be influenced by a variety of factors including its structural complexity and the nature of the solvent used. As always, it is essential to conduct experimental assays to determine its precise solubility characteristics under various conditions.

Interesting facts

Interesting Facts About the Compound

The compound known as (2R,3R,4S,5R)-5-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-(pyridine-3-carbonyloxymethyl)tetrahydrofuran-2-yl methyl pyridine-3-carboxylate represents a fascinating intersection of organic chemistry and medicinal applications. With its intricate structure, this compound showcases several noteworthy attributes:

  • Synthetic Versatility: The presence of the pyridine moieties in the structure highlights its potential as a scaffold for the synthesis of complex organic molecules.
  • Biological Relevance: Compounds featuring pyridine and tetrahydrofuran rings are often investigated for their biological activity, particularly in the realm of pharmaceuticals. This compound may exhibit interesting pharmacological properties.
  • Chirality: The compound has multiple stereocenters, leading to different stereoisomers. This aspect can significantly influence the compound's biological activity and interactions with biological targets.
  • Research Interest: Researchers are increasingly focused on compounds that possess multiple functional groups, such as carboxylates and hydroxyls, as they may display unique reactivity and adaptability in various chemical reactions.

As noted by chemist Dr. Eliza Hart, “The complexity of organic molecules often dictates their usefulness in drug design and development.” This statement resonates well with the study of this compound, revealing how intricate structures can lead to significant discoveries.

In summary, the examination of (2R,3R,4S,5R)-5-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-(pyridine-3-carbonyloxymethyl)tetrahydrofuran-2-yl methyl pyridine-3-carboxylate offers a rich canvas for exploration in both academic research and practical applications, highlighting the beauty and complexity of chemical compounds.

Synonyms
NICOFURANOSE
15351-13-0
Bradilan
Nicofuranosa
Vasperdil
Nicofuranoso
Nicofuranosum
Tetranicotinoylfructose
Nicofuranoso [DCIT]
ES 304
Nicofuranosum [INN-Latin]
Nicofuranosa [INN-Spanish]
Nicofuranose [INN:BAN:DCF]
EINECS 239-385-7
ES-304
Nicofuranose (INN)
D-Fructofuranose 1,3,4,6-tetranicotinat
DTXSID6023365
D-Fructofuranose 1,3,4,6-tetranicotinate
GF99P6327K
1,3,4,6-Tetra-O-nicotinoyl-D-fructofuranose
NICOFURANOSE [MI]
NICOFURANOSE [INN]
NICOFURANOSE [MART.]
NICOFURANOSE [WHO-DD]
DTXCID703365
[(2R,3R,4S,5R)-5-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-(pyridine-3-carbonyloxymethyl)oxolan-2-yl]methyl pyridine-3-carboxylate
Nicofuranosum (INN-Latin)
Nicofuranosa (INN-Spanish)
NICOFURANOSE (MART.)
nicofurazone
((2R,3R,4S,5R)-5-hydroxy-3,4-bis(pyridine-3-carbonyloxy)-5-(pyridine-3-carbonyloxymethyl)oxolan-2-yl)methyl pyridine-3-carboxylate
C10AD03
1,3,4,6-tetranicotinoyl fructose
1,3,4,6-tetranicotinoyl fructofuranose
239-385-7
12041-87-1
Tetranicotylfructose
Tetranicotylfructofuranose
Fructofuranose, tetranicotinate
UNII-GF99P6327K
NCGC00159394-02
MLS006010652
SCHEMBL406596
CHEMBL1697844
CHEBI:135846
FUWFSXZKBMCSKF-ZASNTINBSA-N
Tox21_111631
AKOS025392170
DB13422
KS-1425
SMR004701648
XN176250
CAS-15351-13-0
NS00004059
D07189
SR-01000944867
Q3295509
SR-01000944867-1
1,3,4,6-tetrakis-O-(pyridin-3-ylcarbonyl)-beta-D-fructofuranose