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Monensin

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Identification
Molecular formula
C36H62O11
CAS number
17090-79-8
IUPAC name
(2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2S,3R,5S)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methyl-pentanoic acid
State
State

At room temperature, Monensin is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
670.92g/mol
Molar mass
670.9150g/mol
Density
1.2706g/cm3
Appearence

Monensin typically appears as a white to off-white crystalline powder. It is not known for having a distinct odor and is visually amorphous.

Comment on solubility

Solubility of (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2S,3R,5S)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methyl-pentanoic acid

This complex compound features numerous functional groups which significantly influence its solubility characteristics. In general, the solubility of a substance can be assessed by considering a few key factors:

  • Polarity: The presence of polar hydroxyl (-OH) groups typically enhances solubility in polar solvents, such as water.
  • Hydrophobic regions: Conversely, hydrophobic alkane or cycloalkane chains can lead to decreased solubility in polar media.
  • Molecular weight: Higher molecular weight compounds often exhibit reduced solubility due to increased van der Waals forces.
  • Hydrogen bonding: The ability to form hydrogen bonds can dramatically improve solubility in polar solvents.

Given the intricate structure of this compound, which combines hydrophilic and hydrophobic elements, one might expect varied solubility behaviors. It is likely to have limited solubility in nonpolar solvents while being more soluble in slightly polar solvents. However, detailed solubility tests are necessary for precise predictions.

In summary, solubility is influenced by a balance of the above factors, and for this compound, interactions between its functional groups will ultimately dictate its solubility profile. As the saying goes, "Like dissolves like", which underlines the significance of the molecular structure in determining solubility.

Interesting facts

Exploring the Unique Compound: (2R,3S,4R)-4-[(2R,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2S,3R,5S)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methyl-pentanoic acid

This compound is intricate, showcasing the complexity and beauty of organic chemistry. Its structure is a stunning example of stereochemistry, featuring multiple chiral centers that contribute to its unique properties and potential biological activities.

Key Facts About This Compound:

  • Natural Products: It is often derived from natural sources, hinting at potential medicinal properties that could be harnessed in pharmaceuticals.
  • Stereochemistry: The assignment of configuration (R/S) at several asymmetric centers is critical for understanding its biological activity — even small changes can lead to different effects.
  • Applications: Due to its complex structure, this compound may be of interest in the research of novel drugs, especially in the realm of anti-inflammatory or anti-cancer therapies.
  • Research Potential: Its intricate arrangement of hydroxyl and methoxy groups indicates potential for diverse reactivity and interactions, making it a valuable subject for further exploration in synthetic organic chemistry.

The beauty of compounds like this lies not just in their complexity, but in the scientific stories they can tell. Each chiral center holds potential for the development of solutions to significant health issues, embodying the intersection of nature, science, and innovation. As chemists, we are continually inspired by such compounds, propelling our quest for knowledge and discovery.

Synonyms
CHEMBL261814
SCHEMBL16931530
Q63393051