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Uridine diphosphate glucose

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Identification
Molecular formula
C15H24N2O17P2
CAS number
133-89-1
IUPAC name
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate
State
State

At room temperature, uridine diphosphate glucose is generally in a solid state. It exists typically as a crystalline powder and may be stored in airtight containers to prevent it from absorbing moisture from the air, which could alter its physical state.

Melting point (Celsius)
164.50
Melting point (Kelvin)
437.50
Boiling point (Celsius)
600.00
Boiling point (Kelvin)
873.00
General information
Molecular weight
566.31g/mol
Molar mass
566.3090g/mol
Density
1.6500g/cm3
Appearence

Uridine diphosphate glucose (UDP-glucose) is typically a white to off-white powder. It is a hydrophilic compound, meaning it has a strong tendency to interact with water molecules, and as such, it may appear slightly hygroscopic, readily absorbing moisture from the atmosphere.

Comment on solubility

Solubility Characteristics

The compound [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate is an intricate molecule with a complex structure that impacts its solubility properties.


Key points about its solubility include:

  • Hydrophilicity: Due to the presence of multiple hydroxyl (-OH) groups, this compound exhibits a strong hydrophilic character, which often leads to high solubility in aqueous solutions.
  • Interactions: The hydrogen-bonding capabilities of the hydroxyl groups facilitate interactions with water molecules, enhancing the compound's solubility.
  • Solvent Specificity: While likely soluble in water, the compound's solubility may vary in organic solvents, potentially being less soluble in non-polar solvents due to its polar nature.
  • Temperature Dependence: Solubility can also be temperature-dependent, where increased temperature might improve dissolution rates in some solvents.

In conclusion, the unique chemical structure of this compound implies that while it is expected to be soluble in water and some polar solvents, its solubility in non-polar environments is anticipated to be minimal, making it a compound that is better suited for aqueous phase applications.

Interesting facts

Interesting Facts about the Compound

This compound, known for its complex structure and significant biological properties, has garnered attention in both medicinal and biochemical fields. Here are some intriguing insights about this remarkable molecule:

  • Biochemical Significance: This compound plays a vital role in the metabolic processes of living organisms. It is involved in the regulation of various cellular functions, making it a key player in biochemistry.
  • Structural Complexity: The intricate arrangement of its multiple hydroxy groups and the unique tetrahydrofuran and tetrahydropyran rings contributes to its diverse reactivity and interaction with biological substrates.
  • Potential Therapeutic Applications: Due to its ability to influence important biochemical pathways, this compound is being investigated as a potential drug candidate in the treatment of specific diseases, especially those related to metabolic disorders.
  • Phosphoryl Group Importance: The presence of the phosphoryl group enhances its biological functionality. Phosphorylation is a common regulatory mechanism, and compounds like these are essential in cell signaling and regulatory functions.
  • Stereochemistry: The specific stereochemistry of the molecule (with labeled R and S configurations) is crucial; even small changes in stereochemistry can lead to vastly different biological activities. As such, the study of enantiomers and diastereomers in this context is a rich area of research.

In summary, this compound serves as a fascinating subject for scientists and researchers, offering insights into the intricate interplay between structure and function in biological chemistry. Its potential as a therapeutic agent underscores the importance of exploring complex molecules in drug development. As the famous chemist, Linus Pauling, once said, “The best way to have a good idea is to have lots of ideas,” and compounds like this inspire innovative thinking in chemical research and healthcare.

Synonyms
UDP-galactose
uridine diphosphate galactose
2956-16-3
Udp galactose
UDP-D-galactopyranose
Uridine pyrophosphogalactose
Uridinediphosphogalactose
GALACTOSE-URIDINE-5'-DIPHOSPHATE
UDP-alpha-D-Galactose
Udpgal
UDP-Gal
Uridine diphosphategalactose
Uridine diphosphogalactose
[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
Uridinediphosphate galactose
O2HY4WY2W1
CHEMBL439009
Uridine diphosphate-D-galactose
CHEBI:67119
UDP-alpha-D-galactopyranose
Uridine 5'-diphosphogalactose
Uridine-5'-diphosphate-alpha-D-galactose
GDU
UDPgalactose
Uridine 5'-(alpha-D-galactopyranosyl pyrophosphate)
UDP-a-D-Galactose
Uridine 5'-(trihydrogen diphosphate), P'-alpha-D-galactopyranosyl ester
Uridine 5'-(trihydrogen diphosphate), P'-a-D-galactopyranosyl ester
UDP-delta-galactose
Udp-delta-galactopyranose
UDP-alpha-delta-Galactose
bmse001024
UNII-O2HY4WY2W1
GTPL1782
SCHEMBL1521203
Uridine 5'-(trihydrogen diphosphate), P'-.alpha.-D-galactopyranosyl ester
DTXSID60903962
HSCJRCZFDFQWRP-ABVWGUQPSA-N
Uridine diphosphate-delta-galactose
Galactose-Uridine-5''-Diphosphate
BDBM50209668
DB03501
Uridine 5'-pyrophosphate D-galactosyl ester
NS00015113
Uridine 5'-pyrophosphate a-D-galactosyl ester
Uridine 5'-pyrophosphate, D-galactosyl ester
Uridine pyrophosphate a-D-galactopyranosyl ester
Q259015
Uridine 5'-pyrophosphate a-delta-galactosyl ester
Uridine 5'-pyrophosphate alpha-D-galactosyl ester
Uridine 5'-pyrophosphate a-D-galactopyranosyl ester
Uridine 5'-pyrophosphate, alpha-D-galactosyl ester
Uridine pyrophosphate a-delta-galactopyranosyl ester
Uridine pyrophosphate alpha-d-galactopyranosyl ester
Uridine 5'-pyrophosphate alpha-delta-galactosyl ester
Uridine pyrophosphate, alpha-D-galactopyranosyl ester
Uridine 5'-(alpha-delta-galactopyranosyl pyrophosphate)
Uridine 5'-pyrophosphate a-delta-galactopyranosyl ester
Uridine pyrophosphate alpha-delta-galactopyranosyl ester
URIDINE 5'-(.ALPHA.-D-GALACTOPYRANOSYL PYROPHOSPHATE)
uridine 5'-[3-(alpha-D-galactopyranosyl) dihydrogen diphosphate]
Uridine 5'-pyrophosphate, alpha-D-galactopyranosyl ester (6CI,7CI)
Uridine 5'-(trihydrogen diphosphate), P'-a-D-galactopyranosyl ester (9CI)
Uridine 5'-(trihydrogen pyrophosphate), mono-alpha-D-galactopyranosyl ester (8CI)
((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl) dihydrogen diphosphate
[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name)
{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid