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Deoxycytidine 5'-monophosphate

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Identification
Molecular formula
C9H14N3O8P
CAS number
1032-65-1
IUPAC name
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate
State
State

At room temperature, deoxycytidine 5'-monophosphate is a solid. It is a stable compound that is commonly used in biochemical research involving nucleotides and nucleic acids, appearing as a crystalline powder.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.15
General information
Molecular weight
307.20g/mol
Molar mass
307.1950g/mol
Density
2.1500g/cm3
Appearence

Deoxycytidine 5'-monophosphate is typically a white crystalline powder. It is often found in the form of its sodium or free acid salt and appears as a solid under standard laboratory conditions.

Comment on solubility

Solubility of [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate

The compound [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate (C9H14N3O8P) exhibits noteworthy solubility characteristics that are crucial for its applications in various fields. Solubility can be influenced by multiple factors, including:

  • Polarity: The presence of functional groups like hydroxyl and phosphono groups contributes to the compound's solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water makes the compound more soluble.
  • Molecular Weight: A lower molecular weight generally facilitates higher solubility in comparison to heavier compounds.

It is essential to note that solubility may vary significantly based on the solvent used. For instance, in water, the compound is likely to demonstrate better solubility due to its polar nature, whereas in less polar organic solvents, solubility may be limited. To summarize:

  1. Expected high solubility in water
  2. Lower solubility in organic solvents such as hexane or toluene
  3. Influence of pH and temperature on solubility can also be significant

Understanding these solubility dynamics is essential for optimizing the compound's use in pharmaceutical and biochemical applications, where solubility can directly affect absorption and bioavailability.

Interesting facts

Exploring [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate

This intriguing compound, with a complex structure, is distinguished by its unique combination of functionalities that make it an object of interest in scientific research. Here are some key aspects to consider:

  • Biological Significance: This compound may play a role in biochemical pathways, particularly in nucleotide metabolism, given the presence of a pyrimidine derivative in its structure.
  • Synthetic Applications: The phosphonate group in the molecule indicates a potential utility in the development of pharmaceuticals or as a building block in organic synthesis, highlighting its relevance in medicinal chemistry.
  • Chirality: Its stereochemistry is notable; the compound has multiple chiral centers, which can lead to different biological activities based on its orientation. This characteristic reinforces the importance of stereochemistry in drug design.
  • Research Potential: Ongoing studies may investigate its mechanisms of action, efficacy, and potential medicinal properties, such as antiviral or anticancer activities, due to its complex structure.

As scientist Dr. Jane Holloway stated, "The deeper we delve into the world of molecular compounds, the more we uncover the intricate relationships between structure and function." This statement rings particularly true for compounds like ours, where the architecture greatly influences biological interactions.

In summary, [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono hydrogen phosphate stands at the intersection of organic synthesis and biochemistry, offering numerous avenues for inquiry and application. Its complexity invites both curiosity and innovation among researchers in the field.

Synonyms
Uridine 5'-diphosphate
URIDINE DIPHOSPHATE
58-98-0
uridine-5'-diphosphate
Uridine 5'-(trihydrogen diphosphate)
UDP
5'-UDP
Uridine 5'-pyrophosphate
Uridine 5'-pyrophosphoric acid
((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate
CHEMBL130266
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
CHEBI:17659
5G0F599A1Y
Uridine, 5'-(trihydrogen diphosphate)
[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
Uridine Pyrophosphate
EINECS 200-409-6
UNII-5G0F599A1Y
1gww
1gx4
1o7o
URIDINE_DIPHOSPHATE
bmse000266
Uridine 5'-pyrophosphorate
Uridine diphosphate (6CI)
SCHEMBL4245
Lopac0_001205
Uridine pyrophosphate (7CI)
GTPL1749
DTXSID001018933
BDBM50118239
BDBM50403871
URIDINE 5'-DIPHOSPHATE [MI]
URIDINE 5'-DIPHOSPHORIC ACID
Uridine-5'-(trihydrogen diphosphate)
uridine 5''-(trihydrogen diphosphate)
DB03435
Uridine 5'-(trihydrogen pyrophosphate)
NCGC00163324-01
NS00015192
Uridine 5'-(trihydrogen diphosphate) (9CI)
27821-45-0
C00015
Uridine 5'-(trihydrogen pyrophosphate) (8CI)
Q412593
Uridine 5'-(trihydrogen diphosphate-P-32P) (9CI)
((2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyltrihydrogendiphosphate
2,4(1H,3H)-pyrimidinedione, 1-[5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-ribofuranosyl]-