Interesting facts
Interesting Facts about [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4R)-2,3,4-trihydroxy-5-oxo-pentyl] hydrogen phosphate
This compound is a fascinating example of the intricate chemistry that underlies biological molecules. Here are some compelling aspects that highlight its significance in the field of chemistry:
- Role in Biology: This compound plays a critical role as a nucleotide or nucleotide analogue, which is foundational for DNA and RNA synthesis. Its structural components are essential in genetic encoding and expression.
- Structural Complexity: The presence of a tetrahydrofuran ring and multiple hydroxyl groups contributes to its chemical reactivity and interaction with biological systems, showcasing the marvels of organic synthesis.
- Phosphate Group Importance: The inclusion of the phosphate moiety is crucial, as it not only contributes to the molecule's stability but also impacts its role in energy transfer, signaling, and metabolism within cells.
- Research Applications: Compounds like this are often at the forefront of pharmaceutical research, particularly in developing antiviral and anticancer therapies, due to their ability to mimic or interfere with nucleotide functions.
- Chirality and Stereochemistry: With multiple stereocenters, this compound exemplifies chirality's importance in biological interactions, as enantiomers can exhibit drastically different biological activities.
As a student or a scientist, studying compounds like this provides a window into the complexities of biochemical interactions and the potential for innovative drug design. The intricate balance of structure and function serves as a reminder of the wonders of chemistry in life sciences.
In the words of Richard Feynman, "The beauty of a flower is an expression of its conformation and its interaction with the environment." Similarly, the beauty of this compound lies in its detailed structure and function in biological contexts.
Synonyms
ADP Ribose
Ribose adenosinediphosphate
20762-30-5
ADPR
XV3S4KV26E
5'-Diphosphoribose, Adenosine
5-(Adenosine 5'-pyrophosphoryl)-D-ribose
Adenosine 5'-pyrophosphate, 5'-5-ester with D-ribofuranose
Ribose, ADP
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl] hydrogen phosphate
Diphosphoribose, Adenosine
Adenosine 5' Diphosphoribose
Diphosphate Ribose, Adenosine
Ribose, Adenosine Diphosphate
(((2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-hydroxyphosphoryl) ((2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl) hydrogen phosphate
((2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methyl (hydroxy-((2R,3R,4R)-2,3,4-trihydroxy-5-oxopentoxy)phosphoryl) hydrogen phosphate
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy-[(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentoxy]phosphoryl] hydrogen phosphate
(((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(hydroxy)phosphoryl)oxy)((((2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl)methoxy))phosphinic acid
((5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-hydroxyphosphoryl) (3,4,5-trihydroxyoxolan-2-yl)methyl hydrogen phosphate
Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose
Adenosine Diphosphate Ribose
ADPribose
RefChem:109824
Adenosine diphosphoribose
ADPR (nucleotide)
Adenosine pyrophosphate-ribose
JNT
[32P]-ADP-ribose
UNII-XV3S4KV26E
GTPL2444
orb2944747
SCHEMBL29354292
MSK161970
Adenosine 5'-diphosphate, D-ribose ester
Adenosine 5'-diphosphate, D-ribose ester (6CI)
Q27074316
Adenosine 5'-(trihydrogen diphosphate), P'-->5-ester with D-ribose
Adenosine 5'-pyrophosphate, 5'-5-ester with D-ribofuranose (7CI)
Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose (9CI)
Adenosine 5'-(trihydrogen pyrophosphate), 5'-5-ester with D-ribofuranose
Ribofuranose, 5-5'-ester with adenosine 5'-(trihydrogen pyrophosphate), D-
Adenosine 5'-(trihydrogen pyrophosphate), 5'-5-ester with D-ribofuranose (8CI)
Ribofuranose, 5-5'-ester with adenosine 5'-(trihydrogen pyrophosphate), D- (8CI)
Solubility Insights
The solubility of the compound [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3R,4R)-2,3,4-trihydroxy-5-oxo-pentyl] hydrogen phosphate can be described through various factors that contribute to its behavior in different solvents.
Factors Influencing Solubility
In general, such compounds tend to be more soluble in strongly polar solvents due to the intramolecular and intermolecular forces at play. Additionally, as a phosphate derivative, it may exhibit high solubility in biological systems because phosphates are known to interact favorably with water.
Despite these potential solubility characteristics, the exact solubility can vary widely based on experimental conditions such as temperature, pH, and presence of other solutes. Thus, careful empirical validation is often necessary to determine precise solubility values for this complex structure.