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Adenosine triphosphate

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Identification
Molecular formula
C10H16N5O13P3
CAS number
56-65-5
IUPAC name
[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]amino]phosphonic acid
State
State

ATP is typically found as a solid white powder in pure form, but in biological systems, it is primarily found dissolved in the cytoplasm and organelles of cells as a part of cellular metabolism.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
507.18g/mol
Molar mass
507.1810g/mol
Density
1.5000g/cm3
Appearence

Adenosine triphosphate (ATP) typically appears as a white crystalline powder when isolated. In biological systems, it exists dissolved in the aqueous environment of cells.

Comment on solubility

Solubility of (2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]amino]phosphonic acid

The compound (2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]amino]phosphonic acid is known to possess distinct solubility characteristics, influenced by its structural components. Here are some insights on its solubility:

  • Solvent Compatibility: This compound generally shows solubility in polar solvents, such as water, due to the presence of hydroxyl (-OH) groups and the phosphoryl functional groups which can engage in hydrogen bonding.
  • Hydrophilicity: The numerous hydrophilic groups, particularly the phosphoryl and hydroxyl moieties, enhance the compound's affinity for water, thus promoting solubility.
  • Ionic Nature: The presence of an amino group may impart some ionic character, further increasing its ability to dissolve in aqueous solutions.
  • Concentration Effects: As with many organic compounds, solubility may also vary significantly with concentration; at higher concentrations, precipitation may occur.

In conclusion, while this compound is expected to be soluble in polar environments, the specific conditions such as temperature and pH can greatly influence its solubility profile. Thus, it is valuable to conduct empirical studies under varied conditions to ascertain precise solubility data.

Interesting facts

Interesting Facts about (2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]amino]phosphonic Acid

(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]amino]phosphonic acid is a complex compound with significant biological relevance, especially in the field of biochemistry and pharmaceutical research. Here are some intriguing insights into this multifaceted compound:

  • Biological Activity: This compound exhibits a unique mechanism of action that could play a role in inhibiting certain pathway processes, making it a candidate for potential therapeutic applications.
  • Structural Complexity: The presence of multiple functional groups, such as amino groups and hydroxyl groups, contributes to its reactivity and ability to engage in various biochemical interactions.
  • Amino Purine Connection: Its structural association with aminopurine illustrates its relationship to purine metabolism. This association is critical for the synthesis of nucleotides and nucleic acids, which are fundamental to cellular processes.
  • Synthesis Challenges: The synthesis of such compounds is often complex and may require advanced techniques in organic synthesis, including phosphonylation and stereochemistry control.
  • Potential Research Applications: Due to its intricate structure, it may serve as a scaffold for designing new drugs targeting specific diseases, particularly those related to nucleic acid metabolism.

As scientists delve deeper into the properties and potential applications of this compound, it becomes clear that its intricate molecular structure offers endless opportunities for rewarding research and discoveries in medicinal chemistry.

Synonyms
AMP-PNP
ADENYLYL IMIDODIPHOSPHATE
gamma-Imino-ATP
25612-73-1
AMPPNP
Adenyl imidodiphosphate
beta,gamma-Imido-ATP
[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]amino]phosphonic acid
ATP(beta,gamma-NH)
CHEBI:47785
DTXSID90180289
Adenosine 5'-(beta,gamma-Imino)triphosphate
ATP[beta,gamma-NH]
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid
Adenylylimidodiphosphate
5'-O-(hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl)adenosine
gamma Imido ATP
gamma Imino ATP
gamma-Imido-ATP
Adenylimidodiphosphate
beta,gamma imido ATP
Mg AMP PNP
Mg AMP-PNP
Imidodiphosphate, Adenyl
AMP-PNP, Mg
Imidodiphosphate, Adenylyl
Mg 5' Adenylylimidodiphosphate
5'-O-(hydroxy((hydroxy(phosphonoamino)phosphoryl)oxy)phosphoryl)adenosine
(((((2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-hydroxyphosphoryl)oxy-hydroxyphosphoryl)amino)phosphonic acid
RefChem:388773
DTXCID50102780
5'-Adenylic acid, anhydride with imidodiphosphoric acid (1:1)
114661-04-0
adenyl-5'-yl imidodiphosphate
Formycin A 5'-(betagamma-imido)triphosphate
128811-31-4
O(5')-(1,2-dihydroxy-2-phosphonoaminodiphosphoryl)adenosine
(2R)-2-[[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]METHYL]-5-OXO-1-PYRROLIDINECARBOXYLATE-1,1-DIMETHYLET
p(NH)Ppf
beta,gamma-Imidoadenosine 5'-triphosphate
1bxr
App(NH)p
beta,gamma-Imino-ATP
3b5y
AMP.P[NH]P
Formycin A 5'-(beta-gamma-imido)triphosphate
5-Adenylyl imidodiphosphate
5'-Adenylyl imidodiphosphate
SCHEMBL612075
GTPL2456
orb2941931
CHEMBL1230989
BDBM18134
2a29
Adenylyl beta,gamma-imidodiphosphate
Adenosine beta,gamma-imidotriphosphate
5'-Adenylyl (|A,|A-imidodiphosphate)
DA-70600
5'-Adenylyl (beta,gamma-imidodiphosphate)
beta,gamma-Imino-adenosine 5'-triphosphate
HY-130777
Adenosine 5'-(beta,gamma-imidotriphosphate)
Adenosine 5'-(beta,gamma-iminotriphosphate)
CS-0113351
Q15989037
Imidodiphosphoric acid, monoanhydride with 5'-adenylic acid (8CI)
5'-Adenylic acid, monoanhydride with imidodiphosphoric acid (8CI,9CI)
5'-O-[(S)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]adenosine
adenosine, 5'-O-[hydroxy[[hydroxy(phosphonoamino)phosphinyl]oxy]phosphinyl]-
({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}amino)phosphonic acid
[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]amino]phosphonic acid