Skip to main content

Glucose 6-phosphate

ADVERTISEMENT
Identification
Molecular formula
C6H13O9P
CAS number
56-73-5
IUPAC name
[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxytetrahydropyran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, glucose 6-phosphate is generally found in a solid state, appearing as a powder or crystalline material. It is soluble in water but does not dissolve well in organic solvents.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.15
General information
Molecular weight
260.14g/mol
Molar mass
260.1350g/mol
Density
1.9000g/cm3
Appearence

Glucose 6-phosphate appears as a white or colorless crystalline powder. It is hygroscopic in nature, meaning it readily absorbs moisture from the air. This crystalline compound is often used in biochemical research and can be found in its monohydrate or anhydrous forms.

Comment on solubility

Solubility of [(2R,3S,4S,5R)-3,4,5,6-tetrahydroxytetrahydropyran-2-yl]methyl dihydrogen phosphate

The compound [(2R,3S,4S,5R)-3,4,5,6-tetrahydroxytetrahydropyran-2-yl]methyl dihydrogen phosphate, with the molecular formula C6H13O9P, exhibits distinct solubility characteristics that are intriguing for various applications.

Solubility Characteristics:

  • High Solubility in Polar Solvents: Due to the presence of multiple hydroxyl groups, this compound is likely to be highly soluble in polar solvents such as water. The ability of –OH groups to form hydrogen bonds with water molecules facilitates dissolution.
  • Potential Low Solubility in Non-Polar Solvents: Non-polar solvents may struggle to solvate this compound effectively. The hydrophilic groups dominate its structure, making it less favorable for solubility in non-polar environments.
  • Role of pH: The solubility can also be affected by pH. Given that this compound contains a phosphate group, it could exhibit varying solubility depending on whether the environment is acidic or basic.

As a summary, it is reasonable to conclude that stakeholders utilizing [(2R,3S,4S,5R)-3,4,5,6-tetrahydroxytetrahydropyran-2-yl]methyl dihydrogen phosphate can expect robust solubility in aqueous systems, accompanied by limited solubility in organic solvents. Such characteristics can play a vital role in its application in biochemical processes and formulations.

Interesting facts

Interesting Facts about [(2R,3S,4S,5R)-3,4,5,6-tetrahydroxytetrahydropyran-2-yl]methyl dihydrogen phosphate

This fascinating compound, known as methyl dihydrogen phosphate of a tetrahydroxytetrahydropyran derivative, boasts a unique structure that is of great interest in biochemical and synthetic chemistry. Here are several notable aspects:

  • Chirality and Stereochemistry: The designation (2R,3S,4S,5R) in the name indicates the presence of multiple stereocenters. This chirality plays a crucial role in the compound's biological activities and interactions. Compounds with specific stereochemical configurations can exhibit vastly different behaviors in biological systems.
  • Biological Relevance: The presence of dihydrogen phosphate groups suggests that this molecule could play a role in *energy transfer processes* and *metabolism*, similar to other phosphate-containing compounds like ATP. Phosphate groups are essential for many biological functions, including the formation of nucleotides and the regulation of enzymatic activity.
  • Potential Applications: The unique hydroxyl and phosphate groups may be exploited in drug design and synthesis of *bioactive compounds*. These functionalities can be tailored to optimize interactions with biological targets, potentially leading to therapeutics that could tackle various diseases.
  • Synthesis Considerations: Synthesizing such complex molecules often involves multiple steps, including protecting groups and selective reactions. This process not only refines synthetic techniques but also enhances the understanding of reaction mechanisms and the reactivity of functional groups.
  • Environmental Implications: As phosphates are involved in nutrient cycles, understanding compounds like this one is crucial in the context of ecology and environmental science. Accumulation of phosphates in ecosystems is linked to *eutrophication*, thus studying such compounds can provide insights into mitigating ecological imbalances.

In conclusion, [(2R,3S,4S,5R)-3,4,5,6-tetrahydroxytetrahydropyran-2-yl]methyl dihydrogen phosphate stands as a testament to the complex interplay between synthetic chemistry and biological relevance. Its intricate structure not only invites further exploration but also plays a key role in the development of innovative solutions in medicine and environmental science.

Synonyms
Glucose 6-phosphate
Robison ester
Glc6P
D-glucopyranose 6-phosphate
299-31-0
D-glucopyranose 6-(dihydrogen phosphate)
[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate
{[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
6-O-phosphono-D-glucopyranose
D-Glucose 6-Phosphate Solution (1M in H2O)
D-Glucose 6-Phosphate; Glucose 6-Phosphate; Robison Ester
(((2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl)methoxy)phosphonic acid
((2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl)methyl dihydrogen phosphate
D-glucose-6P
D-glucose-6-P
a-D-glucose 6- phosphate
SCHEMBL48379
alpha-D-Glucose 6- phosphate
CHEBI:4170
GTPL4647
CHEMBL4283156
D-Glucose-6-dihydrogen phosphate
NBSCHQHZLSJFNQ-GASJEMHNSA-N
DTXCID401777212
DTXSID101273823
G57367UD
NS00015226
C00092
D-Glucose, 6-(dihydrogen phosphate) (8CI,9CI)
BRD-A73427433-240-01-3
Q36461529
962672D2-8750-46FD-9A76-E598AA2319DA
(3,4,5,6-tetrahydroxytetrahydropyran-2-yl)methoxyphosphonic acid
D-glucopyranose 6-phosphate (closed ring structure, incomplete stereochemistry)