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Adenosine monophosphate

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Identification
Molecular formula
C10H14N5O7P
CAS number
61-19-8
IUPAC name
[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

At room temperature, adenosine monophosphate is typically in a solid state.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
347.22g/mol
Molar mass
347.2210g/mol
Density
2.1700g/cm3
Appearence

Adenosine monophosphate typically appears as a white, crystalline powder. It is odorless and is soluble in water.

Comment on solubility

Solubility of [(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The solubility of [(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate is an intriguing topic due to its complex nature. This compound, containing both organic and inorganic components, can exhibit varied solubility behaviors depending on several factors:

  • Polarity: The presence of hydroxyl groups and phosphate moieties contributes to the compound's polarity, often suggesting good solubility in polar solvents, particularly water.
  • Amine Functionality: The amino group can interact favorably with water molecules, enhancing solubility through hydrogen bonding.
  • pH Dependency: The protonation state of the phosphate group can alter solubility; at lower pH, the compound may become more soluble due to increased ionic character.

In practical terms, it is often stated that “the solubility of a compound is determined by its ability to interact with the solvent,” which is particularly relevant for this compound. Overall, it is anticipated that this compound will demonstrate significant solubility in aqueous environments, making it suitable for various biological applications. Therefore, for researchers working with this compound, it is crucial to consider the solvent environment and the potential influence of pH on solubility characteristics.

Interesting facts

Interesting Facts about [(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This compound holds a fascinating position in the realm of biochemistry due to its structural similarity to nucleotides, the building blocks of DNA and RNA. Here are some intriguing points to consider:

  • Structural Insight: The presence of a tetrahydrofuran ring and an aminopurine moiety suggests roles in biological processes related to nucleic acids.
  • Biological Relevance: Compounds like this can serve as intermediates or analogs in the synthesis of nucleotides, which are crucial for cellular functions such as replication, transcription, and repair.
  • Potential Therapeutic Applications: The unique combination of components could exhibit pharmacological activities, potentially interacting with enzymes or receptors involved in nucleic acid metabolism.
  • Chirality Matters: The presence of chiral centers in this compound allows for different stereoisomers, which may exhibit distinct biochemical properties, emphasizing the importance of chirality in drug design.
  • Research Opportunities: Given its structural complexity, this compound presents numerous avenues for research into its synthesis, mechanisms of action, and potential as a therapeutic agent.

The exploration of [(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate continues to unveil connections between chemical structure and biological function, paving the way for advancements in both medicinal chemistry and molecular biology.

Synonyms
2'-Deoxyadenosine 5'-(dihydrogen phosphate)
653-63-4
2'-deoxyadenosine-5'-monophosphate
dAMP
2'-Deoxyadenosine 5'-monophosphate
5'-Adenylic acid, 2'-deoxy-
2'-Deoxyadenosine 5'-phosphate
2'-Deoxyadenylic acid
Deoxyadenylic acid
Deoxy-AMP
2'-Deoxy-AMP
Deoxyadenosine 5'-monophosphate
Deoxyadenosine monophosphate
2'-dAMP
Deoxyadenosine 5'-phosphate
Deoxy-5'-adenylic acid
2'-DEOXY-5'-ADENYLIC ACID
2'-Deoxyadenosine monophosphate
d-AMP
2'-Deoxy-5'-adenosine monophosphate
2-Deoxyadenosine-5-monophosphate
PdA (VAN)
[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
MFCD00005753
NSC 77680
NSC 82625
VFR8I97ORM
CHEBI:17713
((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
{[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
5'-Adenylic acid, 2'-deoxy- (9CI)
deoxyadenosine-phosphate
2_-Deoxyadenosine 5_-Monophosphate
2 inverted exclamation marka-Deoxyadenosine 5 inverted exclamation marka-monophosphate
54509-79-4
2'-Deoxy-5'-AMP
C10H14N5O6P
UNII-VFR8I97ORM
2'-Deoxyadenosine-5'-phosphoric acid
5'-dAMP
Deoxyadenylate
NSC-77680
NSC-82625
2'-Deoxyadenosine 5'Monophosphate
2'-Deoxyadenylate
D5M
PdA
EINECS 211-503-1
Deoxy-5'-adenylate
Desoxyadenosinmonophosphat
2'-Deoxy-5'-adenylate
bmse000250
2'-Deoxyadenosine-5'-Monophosphate, free acid
SCHEMBL48174
Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate)
MLS000069642
GTPL5120
2'-deoxyadenosine-5'-phosphate
CHEMBL1206239
DTXSID901034859
HMS2232E10
2'-deoxy-Adenosine 5'-phosphorate
HY-W016009R
HG1052
s3248
AKOS015896800
2'-deoxy-Adenosine 5'-phosphoric acid
CS-W016725
HY-W016009
ND05971
[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
[(3S,2R,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosp hate
NCGC00247026-01
AS-59095
BP-58811
SMR000058246
DB-006103
NS00015110
2'-Deoxyadenosine-5'-monophosphate free acid
2'-Deoxyadenosine-5'-monophosphate (Standard)
C00360
2'-DEOXYADENOSINE-5-MONOPHOSPHATE FREE ACID
Q1874427
207127-57-9 (.H2O)
Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate) (8CI)
2'-Deoxyadenosine 5'-monophosphate, Sigma Grade, 98-100%
Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate) (6CI,8CI)
5'-dAMP free acid;2'-Deoxy-D-adenosine-5'-monophosphate free acid
9H-purin-6-amine, 9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-
2 inverted exclamation marka-Deoxyadenosine -5 inverted exclamation marka-monophosphate free acid