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Fluoxymesterone

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Identification
Molecular formula
C20H29FO3
CAS number
76-43-7
IUPAC name
(2R,5S,17S)-2-fluoro-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
State
State

At room temperature, fluoxymesterone is a solid.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
520.00
Boiling point (Kelvin)
793.15
General information
Molecular weight
336.45g/mol
Molar mass
336.4450g/mol
Density
1.2100g/cm3
Appearence

Fluoxymesterone appears as a white or almost white crystalline powder. It is practically insoluble in water but soluble in alcohols and acetone, giving it the versatility needed for pharmaceutical formulations.

Comment on solubility

Solubility of (2R,5S,17S)-2-fluoro-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

The solubility of (2R,5S,17S)-2-fluoro-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one is an intricate topic that hinges on several chemical properties. Understanding this compound's solubility involves considering the following factors:

  • Polarity: This compound features both fluorine and hydroxyl groups, which can enhance its polar characteristics, potentially increasing its solubility in polar solvents like water.
  • Molecular Weight: With a high molecular weight, the solubility may be lower in water compared to organic solvents.
  • Hydrophobic Regions: The tetradecahydro structure suggests significant hydrophobic regions, which may limit its solubility in water while promoting solubility in non-polar solvents.
  • Solvent Considerations: The choice of solvent is crucial. This compound is expected to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

In summary, the solubility of this compound is likely to be influenced by its unique chemical structure, with polar functional groups promoting solubility in polar environments, while the bulk of its hydrophobic characteristics may favor solubility in non-polar solvents. As the adage goes, "like dissolves like," underscoring the importance of solvent choice in predicting solubility.

Interesting facts

Interesting Facts about (2R,5S,17S)-2-fluoro-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

This fascinating compound belongs to a class of compounds known as steroids, which are characterized by a common structure comprising four fused carbon rings. Its complexity and structure make it a compound of interest in various fields including medicine and pharmacology. Below are some intriguing insights:

  • Steroidal Structure: The compound features a unique steroid core that is often associated with various biological activities, including hormonal regulation.
  • Fluorinated Functionality: The presence of a fluorine atom introduces distinctive properties, potentially enhancing the compound's metabolic stability and altering its biological activity compared to its non-fluorinated counterparts.
  • Hydroxy Group: The hydroxy group at the 17 position is crucial, as it can participate in hydrogen bonding, which may affect the compound's solubility and interaction with biological targets.
  • Potential Applications: The structural characteristics suggest potential applications in developing new pharmaceuticals, particularly in areas targeting hormonal pathways or related physiological processes.
  • Research Interest: Due to its unique properties, this compound may attract attention in research focused on metabolic pathways and the synthesis of new drugs.

Overall, (2R,5S,17S)-2-fluoro-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one represents a sophisticated blend of structure and functionality that is likely to stimulate further exploration in the chemical and medicinal chemistry fields. Scientists might say, "It's not just about the structure, but the potential that it holds!"