Interesting facts
Interesting Facts about (2S)-2-[2-[[(1S)-1-(hydroxymethyl)propyl]amino]ethylamino]butan-1-ol; dihydrochloride
This compound, commonly referred to in scientific circles for its role as a therapeutic agent, holds significant importance in medicinal chemistry. It belongs to a class of molecules that exhibit notable biological activities which can provide insights into various pharmacological mechanisms.
Key Characteristics:
- Dual Functionality: The compound features both amine and alcohol functional groups, which may contribute to its ability to participate in a variety of chemical reactions and interactions with biological systems.
- Chiral Centers: The presence of chiral centers in its structure introduces enantiomeric diversity, potentially altering its biological activity. Methods of stereochemistry help in designing more effective enantiomers.
- Hydroxymethyl Group: The hydroxymethyl group enhances solubility and may play a role in the mechanism of action, providing opportunities for hydrogen bonding within biological systems.
Applications in Medicine:
This compound is often studied for its influence on:
- Metabolic pathways: Understanding its impact on aminobiotic pathways can lead to the development of new treatments.
- Neurotransmission: Its structural features may aid in modulating neurotransmitter levels, making it a candidate for neurological disorders.
- Cardiovascular health: Research into its cardiovascular properties could unveil new therapeutic strategies for heart diseases.
In conclusion, the potential of (2S)-2-[2-[[(1S)-1-(hydroxymethyl)propyl]amino]ethylamino]butan-1-ol; dihydrochloride extends far beyond simple composition. Its complex structure and dynamic properties make it an exciting subject of research for chemists and pharmacologists alike.
Synonyms
Ethambutol dihydrochloride
Ethambutol HCL
1070-11-7
Ethambutol Hydrochloride
Dadibutol
Etapiam
Mycobutol
Tambutol
Ebutol
CL 40881
CCRIS 6606
UNII-QE4VW5FO07
EINECS 213-970-7
QE4VW5FO07
DTXSID4045345
NSC-757022
CL-40881
(+)-2,2'-(Ethylenediimino)-di-1-butanol dihydrochloride
CHEBI:4878
DTXCID2025345
NSC 757022
Ethambutol hydrochloride [USAN:USP:JAN]
1-BUTANOL, 2,2'-(ETHYLENEDIIMINO)DI-, DIHYDROCHLORIDE, (+)-
1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, dihydrochloride, (R-(R*,R*))-
1-BUTANOL, 2,2'(1,2-ETHANEDIYLDIIMINO)BIS-, DIHYDROCHLORIDE, (-(R*,R*))
1-BUTANOL, 2,2'-(1,2-ETHANEDIYLDIIMINO)BIS-, HYDROCHLORIDE (1:2), (2S,2'S)-
ETHAMBUTOL HYDROCHLORIDE (MART.)
ETHAMBUTOL HYDROCHLORIDE [MART.]
ETHAMBUTOL HYDROCHLORIDE (USP-RS)
ETHAMBUTOL HYDROCHLORIDE [USP-RS]
Ethambutol hydrochloride (USAN:USP:JAN)
ETHAMBUTOL HYDROCHLORIDE (EP IMPURITY)
ETHAMBUTOL HYDROCHLORIDE [EP IMPURITY]
ETHAMBUTOL HYDROCHLORIDE (EP MONOGRAPH)
ETHAMBUTOL HYDROCHLORIDE (USP MONOGRAPH)
ETHAMBUTOL HYDROCHLORIDE [EP MONOGRAPH]
ETHAMBUTOL HYDROCHLORIDE [USP MONOGRAPH]
Hydrochloride, Ethambutol
213-970-7
(+)-(s,s)-ethambutol dihydrochloride
(+)-2,2'-(ethylenediimino)di-1-butanol dihydrochloride
(+)-ethambutol dihydrochloride
(+)-n,n'-bis(1-(hydroxymethyl)propyl)ethylenediamine dihydrochloride
(2s,2'e)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride
(2s,2's)-2,2'-(ethylenediimino)bis(butan-1-ol) dihydrochloride
n,n'-bis((2s)-1-hydroxybutan-2-yl)ethane-1,2-diaminium dichloride
Ethambutol (dihydrochloride)
Dexambutol
Servambutol
Etibi
(2S,2'S)-2,2'-(Ethane-1,2-diylbis(azanediyl))bis(butan-1-ol) dihydrochloride
JNG307DJ5X
Ethambutol dihydrochloride, DL-
22196-75-4
(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol;dihydrochloride
(2S)-2-[2-[[(1S)-1-(hydroxymethyl)propyl]amino]ethylamino]butan-1-ol dihydrochloride
NCGC00178864-03
UNII-JNG307DJ5X
(+-)-Ethambutol dihydrochloride
Myambutol (TN)
MFCD21364080
Ethambutoli hydrochloridum
NCGC00016560-01
CAS-1070-11-7
(2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl]amino}ethyl)amino]butan-1-ol dihydrochloride
2,2'-(1,2-Ethanediyldiimino)bis-1-butanol dihydrochloride
SCHEMBL650049
SPECTRUM1500288
(S,S)-N,N'-Bis(1-hydroxy-2-butyl)ethylenediamine Dihydrochloride
CHEMBL3140361
HY-B0535A
(+-)-2,2'-(Ethylenediimino)-di-1-butanol dihydrochloride
HMS1920M18
KUC109574C
(S-(R*,R*))-2,2'-(Ethylenediimino)dibutan-1-ol dihydrochloride
KSC-27-052B
Tox21_110494
CCG-40232
s4004
Ethambutol hydrochloride (JP17/USP)
ETHAMBUTOL HYDROCHLORIDE [JAN]
1-Butanol, (1,2-ethanediyldiimino)bis-, dihydrochloride, (R*,R*)-(+-)-
AKOS024258527
Tox21_110494_1
ETHAMBUTOL DIHYDROCHLORIDE [MI]
ETHAMBUTOL HYDROCHLORIDE [USAN]
FE22851
1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, dihydrochloride, (S-(R*,R*))-
ETHAMBUTOL HYDROCHLORIDE [VANDF]
ETHAMBUTOL HYDROCHLORIDE [WHO-IP]
ETHAMBUTOL DIHYDROCHLORIDE [WHO-DD]
Ethambutol dihydrochloride, antimycobacterial
E1011
SW219109-1
ETHAMBUTOL HYDROCHLORIDE [ORANGE BOOK]
D00878
EN300-123643
ETHAMBUTOLI HYDROCHLORIDUM [WHO-IP LATIN]
Q27106530
Z1486001934
2,2'-[ethane-1,2-diyldi(imino)]dibutan-1-ol dihydrochloride
(2S,2'S)- 2,2'-(Ethylenediimino)bis(butan-1-ol) dihydrochloride
(S,S)-2,2'-(1,2-Ethanediyldiimino)bis-1-butanol Dihydrochloride
1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, dihydrochloride, (R*,R*)-
1-BUTANOL, 2,2'-(ETHYLENEDIIMINO)DI-, DIHYDROCHLORIDE, (+-)-
Ethambutol hydrochloride, European Pharmacopoeia (EP) Reference Standard
(S,S)-2,2'-(1,2-Ethanediyldiimino)-bis-1-butanol dihydrochloride;Dexambutol;Ebutol
1-BUTANOL, 2,2'-(1,2-ETHANEDIYLDIIMINO)BIS-, DIHYDROCHLORIDE, (2R,2'R)-REL-
Ethambutol for system suitability, European Pharmacopoeia (EP) Reference Standard
Ethambutol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
Ethambutol hydrochloride, United States Pharmacopeia (USP) Reference Standard
29326-86-1
Solubility Overview
The compound (2S)-2-[2-[[(1S)-1-(hydroxymethyl)propyl]amino]ethylamino]butan-1-ol; dihydrochloride exhibits intriguing solubility characteristics that can significantly impact its applications and usage in various fields.
Solubility in Water
This dihydrochloride salt form of the compound is expected to be highly soluble in water due to the presence of multiple polar functional groups, including amines and hydroxyl groups. The following aspects contribute to its solubility:
Solubility in Organic Solvents
While this compound is expected to have good aqueous solubility, its solubility in organic solvents may vary:
In conclusion, understanding the solubility behavior of (2S)-2-[2-[[[1S)-1-(hydroxymethyl)propyl]amino]ethylamino]butan-1-ol; dihydrochloride is essential for effective formulation and application. Its strong water solubility combined with selective solubility in organic solvents highlights the importance of solvent choice in various chemical processes.