Interesting facts
Interesting Facts about (2S)-2-[[3,5-Dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic Acid
(2S)-2-[[3,5-Dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid is a fascinating compound with significant relevance in medicinal chemistry and drug development. Here are some intriguing facts about this compound:
- Mechanism of Action: This compound plays a crucial role in the inhibition of specific enzymes involved in purine metabolism, making it a potential candidate for targeting certain types of cancers and autoimmune diseases.
- Structural Insight: The presence of the dichlorobenzoyl group coupled with the pentanedioic acid backbone provides unique chemical properties that enhance biological activity and selectivity.
- Pharmacological Importance: It serves as a structural framework for various drug analogs, showcasing how modifications can lead to diverse pharmacological profiles, which is pivotal in drug design.
- Research Potential: Studies into this compound can reveal insights into its interactions at the molecular level, which may open doors for new therapeutic applications.
- Historical Significance: Compounds with similar structures have historically paved the way for the development of groundbreaking therapies, illustrating the impact of chemical innovation on modern medicine.
As a scientist or chemistry student, understanding the complexities and potentials of such compounds challenges our perception of chemistry's role in real-world applications. The blend of organic chemistry and pharmacology in this compound exemplifies the beauty of molecular design and its implications for human health.
Synonyms
DICHLOROMETHOTREXATE
Dichloroamethopterin
3',5'-Dichloromethotrexate
Methotrexate, dichloro-
3',5'-Dichloroamethopterin
Amethopterin, 3',5'-dichloro-
NCI-C04875
NSC-29630
CCRIS 4602
BRN 0073523
3988 B 129-4
3988-B-129-4
29NS58S465
3',5'-Dichloro-4-amino-4-deoxy-N(sup10)-methylpteroglutamic acid
N-(3,5-Dichloro-4-((2,4-diamino-6-pteridinylmethyl)methylamino)benzoyl)glutamic acid
DTXSID3024996
UNII-29NS58S465
3',5'-Dichloro-4-amino-4-deoxy-N(sup 10)-methylpteroglutamic acid
4-26-00-03834 (Beilstein Handbook Reference)
NSC29630
Glutamic acid, N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
Glutamic acid, N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, L-
L-Glutamic acid, N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
L-Glutamic acid, N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
Glutamic acid, N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-
Glutamic acid, N-[3,5-dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
Glutamic Acid, N-{3,5-dichloro-4-{[(2,4-diamino-6-pteridinyl)methyl]methylamino}benzoyl}-
N-(3,5-Dichloro-4-((2, 4-diamino-6-pteridinylmethyl)methylamino)benzoyl)glutamic acid
N-(3,5-Dichloro-4-((2,4-diamino-6-pteridinylmethyl)methylamino)benzoyl) Glutamic Acid
N-[3,5-Dichloro-4-[(2, 4-diamino-6-pteridinylmethyl)methylamino]benzoyl]glutamic acid
N-[3,5-dichloro-4-[(2,4-diamino-6-pteridinylmethyl)methylamino]benzoyl] glutamic acid
Glutamic acid, N-(3,5-dichloro-4-(((2, 4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
Glutamic acid, N-(3,5-dichloro-4-([(2, 4-diamino-6-pteridinyl)methyl]methylamino)benzoyl)-
Glutamic acid, N-[3,5-dichloro-4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
L-Glutamic acid, N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-(9CI)
L-Glutamic Acid, N-{3,5-dichloro-4-{[(2,4-diamino-6-pteridinyl)methyl]methylamino}benzoyl}-(9CI)
Methotrexate, Dichloro
3'-5'-Dichloromethotrexate
3', 5'-Dichloroamethopterin
Amethopterin, 3',5'-dichloro
DTXCID304996
4-AMINO-10-METHYL-3',5'-DICHLOROPTEROYLGLUTAMIC ACID
Glutamic acid, N-(3,5-dichloro-4-(((2, 4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, L-
Glutamic acid, N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, L-(8CI)
Glutamic Acid, N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-
Glutamic acid, N-[3,5-dichloro-4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(8CI)
Glutamic Acid, N-{3,5-dichloro-4-{[(2,4-diamino-6-pteridinyl)methyl]methylamino}benzoyl}-L-(8CI)
L-Glutamic acid, N-(3,5-dichloro-4-(((2, 4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
L-Glutamic acid, N-[3,5-dichloro-4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-(9CI)
N-(3,5-DICHLORO-4-(((2,4-DIAMINO-6-PTERIDINYL)METHYL)METHYLAMINO)BENZOYL)-GLUTAMIC ACID
N-(3,5-DICHLORO-4-((2,4-DIAMINO-6-PTERIDINYLMETHYL)METHYLAMINO)-BENZOYL)GLUTAMIC ACID
mcehfixeknksrw-lbprgkrzsa-n
nsc 145883
528-74-5
NSC 29630
3,5-Dichloromethotrexate
(2S)-2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid
(3,5-dichloro-4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid
N-(3,5-dichloro-4-((2,4-diamino-6-pteridinyl)methyl)methyl)methylaminobenzoylglutamic acid
CHEMBL3137680
SCHEMBL10653854
3',5'-Dichloromethotrexate; Methotrexate, dichloro-; NSC 145883; NSC 29630
AKOS040746763
HY-105969
(2S)-2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid
2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid
L-Glutamic acid, N-[[(2,4-diamino-6-pteridinyl)methyl][methyl]amino]-3,5-dichlorobenzoyl]-
N-(3,5-dichloro-4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)- L-Glutamic acid
N-(3,5-Dichloro-4-[[(2,4-diamino-6-pteridinyl)methyl](methyl)amino]benzoyl)glutamic acid #
Solubility of (2S)-2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid
The solubility of (2S)-2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid can be described with an extensive focus on various factors that influence its behavior in solution.
Factors Affecting Solubility
Additionally, it is important to consider the following points:
In conclusion, the solubility of (2S)-2-[[3,5-dichloro-4-[(2,4-diaminopteridin-6-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid is influenced by its molecular structure, polarity, and the solution's pH. Understanding these factors is critical for predicting its behavior in various chemical contexts.