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L-Tyrosine phosphate

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Identification
Molecular formula
C9H12NO6P
CAS number
6695-21-8
IUPAC name
(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid
State
State

At room temperature, L-Tyrosine phosphate is typically a solid that is stable under standard laboratory conditions.

Melting point (Celsius)
257.00
Melting point (Kelvin)
530.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
257.17g/mol
Molar mass
257.1670g/mol
Density
1.7000g/cm3
Appearence

The compound appears as a white crystalline solid, which may be granular in nature. It is generally water-soluble and can appear as a powder or small crystals, depending on the specific formulation or preparation method.

Comment on solubility

Solubility of (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid

The solubility of (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid, often referred to as an amino acid with a phosphonate group, can be understood through several key factors:

  • Polar Nature: The presence of the phosphonooxy group contributes to the overall polarity of the molecule, enhancing its ability to interact with polar solvents such as water.
  • Hydrogen Bonding: The molecule can participate in significant hydrogen bonding, which aids in its dissolution in aqueous environments.
  • pH Sensitivity: As an acidic compound, its solubility can vary with changes in pH, potentially increasing in basic conditions where the carboxylic group can deprotonate.

It is noted that many amino acids and their derivatives, particularly those containing phosphonate groups, are generally soluble in water due to these factors. This solubility can be affected by specific environmental conditions, making it essential to consider:

  1. Temperature: Higher temperatures typically facilitate greater solubility.
  2. Concentration: At certain concentrations, solubility limits may be reached, leading to precipitation.
  3. Presence of Salts: The addition of salts can either enhance or decrease solubility through ionic interactions.

As such, understanding the solubility of (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid is critical for applications in biochemical processes and pharmaceutical formulations.

Interesting facts

Interesting Facts about (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid

(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid, often referred to as a phosphono analog of amino acids, presents some fascinating aspects from both a scientific and therapeutic standpoint. This compound is of significant interest primarily due to its structural characteristics that enable it to interact with various biological systems.

Key Features

  • Amino Acid Derivative: This compound is a modified amino acid, exhibiting properties that can influence neurotransmission and physiological functions.
  • Phosphonate Group: The presence of a phosphono group suggests potential applications in biochemical pathways involving phosphate transfer, impacting cellular signaling processes.
  • Pharmacological Relevance: Research indicates that such compounds can act as inhibitors or modulators of important enzymes, making them candidates for drug development in treating various conditions.

Applications and Implications

The implications of this compound extend to various fields:

  • Neuroscience: As an analog to neurotransmitters, it may play a role in studying neural pathways and understanding excitatory neurotransmission.
  • Drug Development: Compounds like this have potential roles in the creation of pharmaceuticals targeting neurological disorders or metabolic dysfunctions.
  • Biochemical Research: It serves as a valuable tool for scientists investigating the dynamics of amino acid pathways and phospholipid metabolism.

Scientific Insights

From a chemical perspective, the balance between its structural attributes and biological activities makes (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid a unique subject of study. As stated by researchers in the field, “The exploration of amino acid derivatives often unveils critical targets for therapeutic intervention." Thus, this compound continues to inspire investigations into its therapeutic potentials and mechanisms of action.

As science progresses, the understanding of compounds like (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid can lead to breakthroughs in medicine and biology, showcasing the intricate relationship between chemistry and life sciences.

Synonyms
21820-51-9
Phosphonotyrosine
PHOSPHOTYROSINE
Phospho-L-tyrosine
2R86C98KDX
L-Tyrosine, dihydrogen phosphate (ester)
DTXSID00176234
(2S)-2-amino-3-[4-(phosphonooxy)phenyl]propanoic acid
(2S)-2-amino-3-(4-(phosphonooxy)phenyl)propanoic acid
tyrosine-o-phosphate
Tyrosine O phosphate
RefChem:863006
DTXCID9098725
O-Phospho-L-tyrosine
O-Phosphotyrosine
H-Tyr(H2PO3)-OH
Tyrosine O-phosphate
L-Tyrosine-O-phosphate
L-Phosphotyrosine
MFCD00002603
H-Tyr(PO3H2)-OH
(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid
Phosphotyrosine (pY)
O-phosphono-L-tyrosine
L-tyrosine, O-phosphono-
L-3-(4-Hydroxyphenyl)alanine 4'-phosphate
CHEBI:37788
C9H12NO6P
pTyr
tyrosine phosphate
H-Tyr(PO)-OH
O(4)-phospho-L-tyrosine
SCHEMBL1152
O(4)-phosphono-L-tyrosine
Tyrosine, phosphate (6CI)
UNII-2R86C98KDX
CHEMBL286939
BDBM22597
Tyrosine, di-H phosphate (7CI)
GLXC-10443
L-TYROSINE-O-PHOSPHORIC ACID
MSK170664
AKOS015856720
AKOS015894042
CS-W012494
DB01962
FP27018
HY-W011778
AS-19190
SY074218
DB-231601
J208.898C
H-Tyr(H2PO3)-OH; L-Tyrosine-O-phosphate
NS00068548
P0959
O-Phospho-L-tyrosine (H-L-Tyr(PO3H2)-OH)
A12281
C06501
EN300-7366217
L-Tyrosine, dihydrogen phosphate (ester) (9CI)
F493251
TYROSINE, DIHYDROGEN PHOSPHATE (ESTER), L-
Tyrosine, dihydrogen phosphate (ester), L- (8CI)
Q19805940
(S)-2-Amino-3-(4-phosphonooxy-phenyl)-propionic-acid
L-3-(4-Hydroxyphenyl)alanine 4'-phosphate;L-Tyrosine-O-phosphate
PHOSPHORIC ACID 4-((S)-2-CARBOXY-2-AMINOETHYL)PHENYL ESTER