Skip to main content

L-Arginine

ADVERTISEMENT
Identification
Molecular formula
C6H14N4O2
CAS number
74-79-3
IUPAC name
(2S)-2-amino-6-guanidino-hexanoic acid
State
State

At room temperature, L-Arginine is typically found as a solid. In its free form, it is usually a white powder.

Melting point (Celsius)
244.00
Melting point (Kelvin)
517.15
Boiling point (Celsius)
535.15
Boiling point (Kelvin)
808.30
General information
Molecular weight
174.20g/mol
Molar mass
174.2030g/mol
Density
1.4000g/cm3
Appearence

Arginine appears as a white crystalline powder in its pure form. It is a basic amino acid and can be found as part of proteins in nature. It is often sold as a dietary supplement, and in this form, it can appear in capsules or tablets.

Comment on solubility

Solubility of (2S)-2-amino-6-guanidino-hexanoic acid

(2S)-2-amino-6-guanidino-hexanoic acid, commonly known as L-arginine, exhibits notable solubility characteristics essential for its biochemical interactions. The solubility of this compound can be summarized as follows:

  • Water Solubility: L-arginine is highly soluble in water, typically at a concentration of around 100 g/L at room temperature. This property facilitates its role in biological systems.
  • Solvent Compatibility: It is sparingly soluble in organic solvents such as ethanol and methanol, indicating its polar nature.
  • pH Influence: The solubility is also affected by pH levels. At acidic pH, its solubility can decrease due to protonation effects, while in an alkaline medium, it remains soluble, allowing for effective utilization in physiological processes.

The polar functionality of the guanidino group and amino groups in the structure leads to strong hydrogen bonding with water, enhancing solubility. Overall, the solubility of (2S)-2-amino-6-guanidino-hexanoic acid is a critical factor that underpins its biological functions, especially in metabolic pathways and nitrogen metabolism.

Interesting facts

Interesting Facts about (2S)-2-amino-6-guanidino-hexanoic acid

(2S)-2-amino-6-guanidino-hexanoic acid, commonly known as arginine, is an essential amino acid that plays a crucial role in many biochemical processes. Here are some compelling aspects of this remarkable compound:

  • Biological Importance: Arginine is a precursor to nitric oxide, a vital signaling molecule involved in regulating blood flow, thus impacting cardiovascular health.
  • Protein Synthesis: As one of the building blocks of proteins, arginine is integral in various physiological functions, aiding in muscle growth and repair.
  • Wound Healing: Studies have shown that arginine may enhance healing processes by promoting collagen formation, crucial for skin and tissue repair.
  • Immune Function: This amino acid plays a crucial role in immune response, supporting the activity of T-cells, which are essential for fighting infections.
  • Hormonal Regulation: Arginine stimulates the release of growth hormone and insulin, highlighting its role in metabolism and endocrine functions.

As a nutrient, arginine is commonly found in foods such as:

  1. Meats
  2. Dairy products
  3. Nuts and seeds
  4. Legumes

Furthermore, arginine's ability to generate nitric oxide has led to its exploration in various therapeutic applications, including:

  • Atherosclerosis treatment
  • Erectile dysfunction management
  • Improving exercise performance

As a fascinating compound, (2S)-2-amino-6-guanidino-hexanoic acid continues to be a subject of extensive research, underscoring its significant biological and medical relevance in the field of biochemistry.

Synonyms
L-Homoarginine
homoarginine
156-86-5
H-HoArg-OH
homo-l-arginine
H-HomoArg-OH
n6-amidino-lysine
L-N(sup 6)-Amidinolysine
N6-amidino-L-Lysine
N6-(Aminoiminomethyl)-L-lysine
L-Lysine, N(sup 6)-(aminoiminomethyl)-
L-Lysine, N6-(aminoiminomethyl)-
NSC 27429
LYSINE, N(sup 6)-AMIDINO-, L-
CHEBI:27747
(2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid
L-N(6)-amidinolysine
L-Lysine, N(6)-(aminoiminomethyl)-
(S)-2-Amino-6-guanidinohexanoic acid
CHEMBL589752
JF751CK38I
DTXSID70926980
Homoarginine, L-
N6-carbamimidoyl-L-lysine
UNII-JF751CK38I
LHomoarginine
h-Homoarginine
MFCD00237108
NSC-27429
NSC-88868
HRG
L-HomoArg-OH
LN(sup 6)Amidinolysine
bmse000745
SCHEMBL43287
LYSINE, N6-AMIDINO-
N(6)-carbamimidoyl-L-lysine
N~6~-carbamimidoyl-L-lysine
Lysine, N(sup 6)amidino, L
LLysine, N6(aminoiminomethyl)
SCHEMBL21802133
DTXCID001355785
LYSINE, N6-AMIDINO-, L-
AC2507
BDBM50309588
s6109
LLysine, N(sup 6)(aminoiminomethyl)
AKOS006282043
AKOS015894481
LLysine, N6(aminoiminomethyl) (9CI)
CS-W008385
DB03974
HY-W008385
13094-78-5
DS-15039
L-Lysine, N6-(aminoiminomethyl)- (9CI)
(2S)-2-amino-6-carbamimidamidohexanoic acid
NS00068514
C01924
(S)-2-Amino-6-guanidinohexanoic acid (H-L-hArg-OH)
Q57828472