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L-Glutamine

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Identification
Molecular formula
C5H10N2O3
CAS number
56-84-8
IUPAC name
(2S)-2,5-diamino-5-oxo-pentanoic acid
State
State

At room temperature, it is a solid.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
146.15g/mol
Molar mass
146.1450g/mol
Density
1.4600g/cm3
Appearence

White crystalline powder.

Comment on solubility

Solubility of (2S)-2,5-diamino-5-oxo-pentanoic acid (C5H10N2O3)

(2S)-2,5-diamino-5-oxo-pentanoic acid is a relatively polar compound due to the presence of multiple functional groups, including amino and carboxyl groups. This polarity influences its solubility characteristics:

  • Water Solubility: Due to its polar nature, (2S)-2,5-diamino-5-oxo-pentanoic acid is expected to be soluble in water. The ability of the amino groups to form hydrogen bonds with water molecules significantly enhances solubility.
  • Solubility in Organic Solvents: The solubility in organic solvents may be limited. Compounds with predominantly polar functional groups tend to have lower solubility in non-polar solvents, making them less effective in hydrophobic environments.

This compound can exhibit the property of amphipathy, where it can dissolve in both polar and less polar environments under certain conditions, though it performs best in aqueous solutions. To summarize:

  1. Highly soluble in water
  2. Limited solubility in non-polar organic solvents

Understanding the solubility of this compound is crucial for its applications in biological systems and chemical reactions, particularly where aqueous conditions are predominant.

Interesting facts

Interesting Facts about (2S)-2,5-diamino-5-oxo-pentanoic acid

(2S)-2,5-diamino-5-oxo-pentanoic acid, commonly referred to as a derivative of a vital amino acid, plays a significant role in various biochemical pathways. Here are some noteworthy points to consider:

  • Amino Acid Derivative: This compound is related to the structure of amino acids, specifically lysine and arginine, which are essential for protein synthesis.
  • Biological Importance: It is involved in the biosynthesis of other important biomolecules, potentially contributing to metabolic processes that influence growth and development.
  • Potential Therapeutic Applications: Researchers are exploring its utility in medicine, particularly in the context of protein engineering and enzyme catalysis.
  • Chemical Versatility: The functional groups within its structure allow for a range of chemical reactions, making it a candidate for various synthetic applications in organic chemistry.
  • Structure-Activity Relationship: Understanding the configuration and activity of this compound can provide insights into how slight changes in molecular structure can influence biological activity and reactivity.

In conclusion, (2S)-2,5-diamino-5-oxo-pentanoic acid serves as an intriguing subject within both the realms of biochemistry and synthetic chemistry. Further studies may reveal more about its potential uses and significance in biological systems.

Synonyms
L-glutamine
glutamine
56-85-9
Levoglutamide
L-(+)-Glutamine
Glutamic acid amide
Cebrogen
Stimulina
glumin
H-Gln-OH
Levoglutamid
(S)-2,5-Diamino-5-oxopentanoic acid
glutamic acid 5-amide
L-Glutamide
2-aminoglutaramic acid
Glavamin
Miglu-P
Nutrestore
Saforis
L-2-Aminoglutaramidic acid
L-Glutamin
L-Glutamic acid gamma-amide
Glumin (amino acid)
(2S)-2-amino-4-carbamoylbutanoic acid
L-2-Aminoglutaramic acid
Glutamine (VAN)
Levoglutamida
Levoglutamidum
L-Glutamic acid 5-amide
FEMA No. 3684
(2S)-2,5-diamino-5-oxopentanoic acid
2-Aminoglutaramic acid, L-
GLUTAMINE, L-
L-gln
Pentanoic acid, 2,5-diamino-5-oxo-, (S)-
Glutamine [USAN]
Levoglutamidum [INN-Latin]
2,5-Diamino-5-oxopentanoic acid, (S)-
Levoglutamida [INN-Spanish]
AI3-24392
glutamina
NSC 27421
Levoglutamina
L-Glutaminsaeure-5-amid
BRN 1723797
L-Glutamid
26700-71-0
EINECS 200-292-1
MFCD00008044
UNII-0RH81L854J
ENDARI
CCRIS 9428
CHEBI:18050
HSDB 8165
0RH81L854J
NSC-27421
CHEMBL930
gln
DTXSID1023100
d(-)-glutamine
glum
4-04-00-03038 (Beilstein Handbook Reference)
GLUTAMINE (D)
Levoglutamide [DCF:INN]
GLUTAMINE (MART.)
GLUTAMINE [MART.]
GLUTAMINE (USP-RS)
GLUTAMINE [USP-RS]
gamma-Glutamine
Hgln
184161-19-1
GLUTAMINE (USP MONOGRAPH)
GLUTAMINE [USP MONOGRAPH]
l glutamine
Glutamine-S
Glutaminsaeure-5-amid
GLUTAMINE,L-
glutamic acid gamma-amide
(2S)-2,5-diamino-5-oxopentanoate
L-Glutamine [JAN]
GLUTAMINE (L)
L-Glutamic acid .gamma.-amide
CHEBI:28300
glutaminum
Glutacerebro
Gebrogen
Glutaven
Memoril
Glutamine [USAN:USP:INN]
GlutaSolve
3h-l-glutamine
Poly-L-glutamine
Q. Levoglutamide
1wdn
(S)-glutamine
[3H]glutamine
Sympt-X
Nutrestore (TN)
S(+)Glutamine
Glutamine (USP)
Glutapak-10
Resource Glutasolve
[14C]glutamine
[3H]-glutamine
L-Glutamine,(S)
S(+)-Glutamine
[14C]-glutamine
H-Gln
Endari (TN)
L-Glutamine-13C?
Sympt-X G.I.
Glutamic acid-5-amide
Spectrum_000131
L-Glutamine [JAN]
starbld0006818
L-Glutamine (standard)
L-Glutaminsaure-5-amid
GLUTAMINE [INN]
SpecPlus_000380
GLUTAMINE [MI]
L-Glutamine (JP18)
Glutamine (L-Glutamine)
Spectrum2_001377
Spectrum3_001416
Spectrum4_001709
Spectrum5_000418
GLUTAMINE [VANDF]
L-Glutamine, 98.5%
bmse000038
bmse001014
L-GLUTAMINE [FCC]
1-2-Aminoglutaramidic acid
L-GLUTAMINE [FHFI]
SCHEMBL7453
L-GLUTAMINE [VANDF]
Lopac0_000549
BSPBio_003092
GTPL723
KBioGR_002038
KBioSS_000591
DivK1c_006476
SPECTRUM1500987
S(+)-Glutamic acid 5-amide
SPBio_001334
L-[3,4-3H(N)]glutamine
LEVOGLUTAMIDE [WHO-DD]
DTXCID503100
GTPL4633
GTPL4634
GLUTAMINE [ORANGE BOOK]
SCHEMBL19240116
SCHEMBL23124227
BDBM18121
HY-N0390R
KBio1_001420
KBio2_000591
KBio2_003159
KBio2_005727
KBio3_002312
L-Glutamine, Cell Culture Grade
MSK1407
L-GLUTAMINE [ORANGE BOOK]
HMS3261N19
HMS3264C03
Pharmakon1600-01300018
Pharmakon1600-01500987
(S)-2,5-Diamino-5-oxopentanoate
HY-N0390
(2S)-2-amino-4-carbamoylbutanoate
Tox21_500549
CCG-38853
NSC759628
NSC760081
s1749
pentanoic acid, 2,5-diamino-5-oxo-
AKOS015854078
(S)-2-Amino-4-carbamoyl-butyric acid
CS-1947
DB00130
FG02552
LP00549
NSC-759628
NSC-760081
SDCCGMLS-0066691.P001
SDCCGSBI-0050532.P005
(S)-2-Aminopentane-dioic acid 5-amide
NCGC00093936-01
NCGC00093936-02
NCGC00093936-03
NCGC00093936-04
NCGC00093936-05
NCGC00093936-15
NCGC00261234-01
AS-11765
BP-13284
DA-54895
SBI-0050532.P003
L-Glutamine, BioUltra, >=99.5% (NT)
EU-0100549
G0063
L-Glutamine, SAJ special grade, >=99.0%
NS00068566
EN300-52640
C00064
D00015
D70833
G 3126
M02960
AB00173347-03
AB00173347_04
L-Glutamine, ReagentPlus(R), >=99% (HPLC)
L-Glutamine, Vetec(TM) reagent grade, >=99%
L-Glutamine, Cell Culture Reagent (H-L-Gln-OH)
Q181619
7FBA778C-D6B8-495C-BFE7-1CB8EC4ABEAB
BRD-K83896451-001-01-8
BRD-K83896451-001-06-7
BRD-K83896451-001-07-5
F0001-1471
L-Glutamine, certified reference material, TraceCERT(R)
Z756440074
(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide
(S)-2,5-Diamino-5-oxopentanoic acid;L-Glutamic acid 5-amide
Glutamine, United States Pharmacopeia (USP) Reference Standard
L-Glutamine, gamma-irradiated, BioXtra, suitable for cell culture
L-Glutamine, Pharmaceutical Secondary Standard; Certified Reference Material
200-292-1
L-Glutamine, meets USP testing specifications, cell culture tested, 99.0-101.0%, from non-animal source