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Levodopa

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Identification
Molecular formula
C9H11N3O4
CAS number
59-92-7
IUPAC name
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid
State
State

Levodopa is typically a solid at room temperature. Given its crystalline nature, it is structured and dense, contributing to its ease of handling in laboratory and pharmaceutical settings.

Melting point (Celsius)
283.00
Melting point (Kelvin)
556.15
Boiling point (Celsius)
802.00
Boiling point (Kelvin)
1 075.15
General information
Molecular weight
197.19g/mol
Molar mass
197.1920g/mol
Density
1.4908g/cm3
Appearence

Levodopa appears as a white or off-white crystalline powder. It is relatively soluble in water, creating a colorless or slightly yellow solution when dissolved. The compound is usually stable in its crystalline form but can darken upon exposure to air or moisture.

Comment on solubility

Solubility of (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid

The solubility of (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid can be influenced by various factors, including its molecular structure and functional groups. This compound features both hydrazino and carboxylic acid groups, which can significantly impact its behavior in aqueous solutions.

Key Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl groups can enhance polarity, promoting solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules increases the likelihood of dissolving in aqueous environments.
  • pH Levels: The acid nature may contribute to solubility changes depending on the pH of the solution.

In summary, it is likely that (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid exhibits moderate to good solubility in water, depending on the conditions. Understanding its solubility behavior is crucial for applications in pharmaceuticals and research, where effective delivery or reaction with biological systems is often essential.

Interesting facts

Interesting Facts about (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic Acid

(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid is a compound that showcases the fascinating interplay between chemistry and biochemistry. This unique molecule is a derivative of hydrazino acids, a class that has attracted attention for their potential applications in medicinal chemistry.

Key Features:

  • Structural Complexity: The compound features a hydrazine functional group, which is quite versatile and often used in the synthesis of various bioactive substances.
  • Phenolic Influence: The presence of the 3,4-dihydroxyphenyl group suggests that this compound may exhibit antioxidant properties, which are crucial in the prevention of oxidative stress in biological systems.
  • Stereochemistry Matters: The designation of (2S) indicates that the molecule has specific stereochemical properties that can significantly affect its biological activity, emphasizing the importance of chirality in drug development.

This compound is not just a complex structure; it holds promise in research due to its possible implications in pharmacology and therapeutic applications. For instance:

  • Bioactivity: Compounds like this one are often investigated for their ability to interact with biological targets, leading to novel treatments for diseases.
  • Synthetic Pathways: Understanding how to synthesize such compounds can pave the way for creating derivatives with enhanced efficacy or reduced side effects.
  • Research Potential: There is ongoing research into hydrazino compounds in various fields, including cancer research and anti-inflammatory studies.

In summary, (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid is an intriguing compound that exemplifies how chemical structures can influence biological functions and therapeutic potential. As the study of such compounds continues, we may unveil even more unexpected applications in health and disease management.

Synonyms
carbidopa
28860-95-9
Lodosyn
Carbidopa anhydrous
(S)-(-)-carbidopa
(S)-carbidopa
alpha-Methyldopahydrazine
N-Aminomethyldopa
Carbidopum
L-alpha-Methyldopahydrazine
Carbidopa (anhydrous)
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
MK 486
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
KR87B45RGH
MK-486
DTXSID4022735
CHEBI:39585
(alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid
DTXCID502735
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, (S)-
Carbidopum monohydrate
NSC-751137
Methyldopahydrazine
DHIVY COMPONENT CARBIDOPA
DUOPA COMPONENT CARBIDOPA
RYTARY COMPONENT CARBIDOPA
CREXONT COMPONENT CARBIDOPA
STALEVO COMPONENT CARBIDOPA
CORBILTA COMPONENT CARBIDOPA
NSC-758190
MK485
Carbidopa Tablets
LEVODOPA/CARBIDOPA/ENTACAPONE ORION COMPONENT CARBIDOPA
L-Carbidopa Anhydrous
RefChem:918027
Carbidopa Tablets, 25 mg
MK486
(2S)-2-(azaniumylamino)-3-(3,4-dihydroxyphenyl)-2-methylpropanoate
Benzenepropanoic Acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-,(S)-
249-271-9
657-445-4
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S)-
CHEBI:3395
MNX7R8C5VO
S-(-)-Carbidopa
Carbidopum [INN-Latin]
S(-)-CARBIDOPA
Carbidopa [INN]
MFCD00069231
(S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
3,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid
CARBIDOPA, L- ANHYDROUS
28860-95-9 (anhydrous)
NCGC00024596-05
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methyl-propanoic acid
Hadrazino-alpha-methyldopa
alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid
C-DOPA
S-(-)-Carbidopa monohydrate
SMR000058235
CCRIS 5093
SR-01000597655
EINECS 249-271-9
UNII-KR87B45RGH
Benzenepropanoic acid, .alpha.-hydrazino-3,4-dihydroxy-.alpha.-methyl-, (S)-
L-alpha-Methyl-alpha-hydrazino-beta-(3,4-dihydroxyphenylpropionic acid
L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alpha-hydrazinopropionic acid
ND0611
Tocris-0455
C-126
CARBIDOPA [WHO-DD]
Lopac0_000382
SCHEMBL35084
MLS000069628
MLS002207014
GTPL5159
orb1300458
CARBIDOPA ANHYDROUS [MI]
CHEMBL1201236
SCHEMBL29392554
GLXC-06131
HMS2089B12
HMS3266A20
HMS3411M13
HMS3655G20
HMS3675M13
HMS3713L10
HMS3884M14
HY-B0311
Tox21_110910
BDBM50418773
NSC751137
S-(-)-alpha-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
s1891
SBB000659
AKOS015969657
HYDROCINNAMIC ACID, alpha-HYDRAZINO-3,4-DIHYDROXY-alpha-METHYL-, L-
AC-1676
CCG-204476
DB00190
SDCCGMLS-0072919.P025
MLS-0072919
SMP1_000057
NCGC00024596-01
NCGC00024596-03
NCGC00024596-06
NCGC00024596-07
NCGC00024596-08
AS-16862
BC164279
ST055523
MLS-0072919.P013
CAS-28860-95-9
C2450
EU-0100382
NS00005042
SW199080-2
60C959
AB00441332-05
AB00441332-06
AB00441332_07
AB00441332_08
EN300-6733817
SR-01000597655-1
SR-01000597655-3
SR-01000597655-5
SR-01000597655-9
BRD-K78712176-001-07-5
BRD-K78712176-001-11-7
BRD-K78712176-001-12-5
BRD-K78712176-001-13-3
BRD-K78712176-001-14-1
Z2301684895
(+)-2-(3,4-Dihydroxybenzyl)-2-hydrazinopropionic acid monohydrate
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinamic Acid
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic Acid
(S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoicacid
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate
Benzenepropanoic acid, .alpha.-hydrazinyl-3,4-dihydroxy-.alpha.-methyl-, (.alpha.S)-
KINSON; 3-(3,4-DIHYDROXY-PHENYL)-2-HYDRAZINO-2-METHYL-PROPIONIC ACID
1426847-87-1