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Threonine

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Identification
Molecular formula
C4H9NO3
CAS number
80-68-2
IUPAC name
(2S,3R)-2-amino-3-hydroxy-butanedioic acid
State
State

At room temperature, threonine is typically found in solid form. It is stable under standard temperature and pressure conditions.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
119.12g/mol
Molar mass
119.1190g/mol
Density
1.6730g/cm3
Appearence

Threonine is crystalline and appears as a white solid. It may also be available in the form of a crystalline powder.

Comment on solubility

Solubility of (2S,3R)-2-amino-3-hydroxy-butanedioic acid

(2S,3R)-2-amino-3-hydroxy-butanedioic acid, more commonly known as L-threonine, exhibits notable solubility characteristics that make it an interesting compound in the study of amino acids. Typically, amino acids are well known for their high solubility in water, and L-threonine is no exception.

Key factors influencing the solubility of L-threonine include:

  • Polarity: The presence of both an amino group (-NH2) and a hydroxyl group (-OH) contributes to the compound's polarity, allowing it to interact favorably with water molecules.
  • Hydrogen Bonding: L-threonine can form hydrogen bonds with water, further enhancing its solubility in aqueous solutions.
  • pH dependence: Its solubility can also vary depending on the pH of the solution, with an increase in solubility observed in slightly acidic to neutral conditions.

In summary, the solubility of (2S,3R)-2-amino-3-hydroxy-butanedioic acid is generally high, making it readily available for biological processes and interactions in cellular environments. As L-threonine dissolves, it readily participates in metabolic pathways, underscoring the importance of understanding solubility in both biochemical and pharmaceutical applications.

Interesting facts

Interesting Facts about (2S,3R)-2-amino-3-hydroxy-butanedioic acid

(2S,3R)-2-amino-3-hydroxy-butanedioic acid, commonly known as threonine, is one of the essential amino acids that our body cannot synthesize and must be obtained through diet. It plays a significant role in protein synthesis and is a key building block for many proteins.

Biological Significance

  • Threonine is vital for the production of collagen and elastin, which are essential for healthy skin and tissues.
  • It supports the immune system by providing the body with the building blocks needed for the production of antibodies.
  • Threonine has a role in metabolism, aiding in the conversion of food into energy.

Nutritional Sources

Natural sources of threonine include:

  • Meat and poultry
  • Dairy products, such as cheese and yogurt
  • Eggs
  • Certain fruits and vegetables, including bananas and beans

Unique Properties

This amino acid possesses the following unique characteristics:

  • It can participate in hydrogen bonding due to its hydroxyl group, contributing to protein structures.
  • Threonine is involved in the synthesis of neurotransmitters such as glycine and serine, further emphasizing its role in the nervous system.
  • Due to its physical properties, it can contribute to the overall stability of protein folds.

Quote to Remember

"Threonine is not just a building block; it is a vital player in maintaining the integrity of our biological systems."

In summary, (2S,3R)-2-amino-3-hydroxy-butanedioic acid is more than just an amino acid; it is integral to numerous biological functions and essential in our diet for maintaining health and supporting metabolic processes.

Synonyms
(3R)-3-hydroxy-L-aspartic acid
7298-98-8
(2S,3R)-2-amino-3-hydroxybutanedioic acid
6532-76-9
erythro-beta-Hydroxyaspartic acid
(3R)-3-Hydroxyaspartate
Erythro-beta-hydroxy-L-aspartic acid
1186-90-9
CHEBI:17576
(2S,3R)-2-amino-3-hydroxysuccinic acid
erythro-3-Hydroxy-L-aspartic acid
GDV0MSK2SG
L-Aspartic acid, 3-hydroxy-, (3R)-
erythro-3-Hydroxy-L-aspartate
CHEMBL3317781
erythro-3-Hydroxy-Ls-aspartic acid
(2S,3R)-2-AMINO-3-HYDROXY-BUTANEDIOIC ACID
erythro-3-Hydroxy-DL-aspartic acid
UNII-GDV0MSK2SG
NSC-158205
EINECS 229-431-4
beta-Hydroxy-L-aspartic acid, erythro-
SCHEMBL336362
erythro-3-hydroxy-Ls-aspartate
(2s,3r)-3-hydroxyaspartic acid
DTXSID201295781
3-HYDROXYASPARTATE, (3R)-
BDBM50055467
3-HYDROXY ASPARTATE, (3R)-
AKOS006274477
DB03640
NSC 119129
NSC 158205
(2S,3R)-2-Amino-3-hydroxysuccinicacid
CS-0438358
NS00068430
C03961
ERYTHRO-.BETA.-HYDROXY-L-ASPARTIC ACID
EN300-1721166
.BETA.-HYDROXY-L-ASPARTIC ACID, ERYTHRO-
Q27094559