Skip to main content

Digoxin

ADVERTISEMENT
Identification
Molecular formula
C41H64O14
CAS number
20830-75-5
IUPAC name
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
State
State
Digoxin is typically found in a solid state at room temperature.
Melting point (Celsius)
249.00
Melting point (Kelvin)
522.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
780.94g/mol
Molar mass
780.9380g/mol
Density
1.2300g/cm3
Appearence

Digoxin appears as a white crystalline powder. It is odorless and has a bitter taste. The compound is known for its cardiac glycoside characteristics and is often presented in an amorphous solid form when used in pharmaceutical preparations.

Comment on solubility

Solubility of (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one

The solubility of this complex organic compound can be influenced by various factors, primarily due to its intricate structure and functional groups. When considering its solubility, the following aspects are noteworthy:

  • Polarity: The presence of multiple hydroxyl (–OH) groups in the molecule typically enhances solubility in polar solvents, such as water, due to hydrogen bonding.
  • Hydrophobic Regions: Conversely, the lipophilic (water-repelling) characteristics of some segments of the compound may limit its solubility in water while increasing solubility in organic solvents.
  • Temperature: Solubility can vary significantly with temperature; generally, an increase in temperature can enhance the solubility of organic compounds.
  • pH Level: The ionization of hydroxyl groups may change in differing pH conditions, affecting solubility in aqueous solutions.

In practical applications, assessing solubility is essential for understanding the compound's behavior in biological systems and its potential applications in pharmaceuticals. Based on these factors, one might conclude that this compound would exhibit moderate solubility characteristics that are context-dependent.

Interesting facts

Interesting Facts about (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one

This compound represents a fascinating example of complex organic chemistry, showcasing the intricate work of nature at the molecular level. It belongs to a class of compounds known for their significant biological activities, particularly in the field of pharmacology and biochemistry.

  • Structure Complexity: The compound features a polycyclic skeletal structure which adds to its chemical diversity and potential reactivity. The presence of multiple stereocenters indicates that it can exist in various isomeric forms, each with potentially different properties and effects.
  • Hydroxyl Groups: With several hydroxyl (-OH) groups, the compound is likely to exhibit strong hydrogen bonding capabilities, influencing its solubility, reactivity, and biological interaction.
  • Natural Occurrence: Compounds of this nature are often found in nature, particularly in plants, where they can function as secondary metabolites playing key roles in defense mechanisms and ecological interactions.
  • Biological Significance: Due to its complex structure, this compound may have implications in therapeutic applications. It could potentially engage biological pathways, making it a candidate for drug discovery and development.

Scientists often say, "The more complex the structure, the richer the potential." The intricate nature of this compound exemplifies this notion, providing ample opportunities for research into its functionality and applications.

In summary, this compound serves as a reminder of the beauty and complexity of the molecular world, inspiring chemists and researchers to explore and uncover the secrets hidden within similar complex structures.

Synonyms
7703-93-7
Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2beta,3beta,5beta,20xi,22R)-
Hydroxyecdysone
DTXSID301156827
(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
PD015577
Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2I(2),3I(2),5I(2),20I(3/4),22R)-