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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(3R,7R,8S,9S,10R,12R)-7-acetoxy-8-methoxy-3,12-dimethyl-5,13-dioxo-10-(2-oxoethyl)-4,17-dioxabicyclo[14.1.0]heptadec-14-en-9-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 3-methylbutanoate
State
State
Erythromycin is a solid at room temperature, typically found in a crystalline powder form.
Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
368.00
Boiling point (Kelvin)
641.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9380g/mol
Density
1.2436g/cm3
Appearence
Erythromycin appears as a white to off-white crystalline powder. It is generally odorless or has a faint characteristic odor and is known for being bitter in taste. The compound tends to degrade upon exposure to light and moisture.
Comment on solubility

Solubility of [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[[3R,7R,8S,9S,10R,12R)-7-acetoxy-8-methoxy-3,12-dimethyl-5,13-dioxo-10-(2-oxoethyl)-4,17-dioxabicyclo[14.1.0]heptadec-14-en-9-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyl-tetrahydropyran-3-yl]oxy-4-hydroxy-2,4-dimethyl-tetrahydropyran-3-yl] 3-methylbutanoate

The solubility of this complex organic compound can be assessed through several key factors:

  • Molecular Structure: The intricate stereochemistry and multiple functional groups present can significantly influence solubility.
  • Polarity: The balance of polar and nonpolar components within the molecule will dictate its solubility in various solvents. Generally, compounds with polar functional groups (like hydroxyl or amine groups) tend to be more soluble in polar solvents (such as water).
  • Hydrogen Bonding: The presence of multiple -OH groups suggests potential for extensive hydrogen bonding, which can enhance solubility in polar environments.
  • Solvent Choice: This compound is expected to exhibit better solubility in organic solvents such as dichloromethane or ethanol, while its solubility in water may be limited.

In conclusion, solubility is influenced by the molecular configuration and the types of functional groups present in the structure. Therefore, one may anticipate that while the compound may show some degree of solubility in polar solvents, it is likely to have better solubility in non-polar organic media. Understanding these pertinent factors is essential for predicting how this compound will behave in different environments.

Interesting facts

Interesting Facts about the Compound

This complex compound, known for its intricate structural characteristics, offers a fascinating glimpse into the world of organic chemistry and biochemistry. Often explored for its potential applications in pharmaceuticals, it showcases several notable features:

  • Stereochemistry: The compound possesses multiple stereocenters, contributing to its unique three-dimensional structure. Stereochemistry plays a crucial role in determining how compounds interact with biological systems, impacting potency and efficacy.
  • Natural Product Derivation: Compounds of this nature are often derived from natural products or mimic their structures. Studying these compounds can lead to the discovery of new drug candidates.
  • Functional Groups: The presence of various functional groups, such as esters and hydroxyls, highlights the compound's chemical versatility, allowing it to participate in numerous chemical reactions.
  • Medicinal Properties: Many complex organic compounds have shown promise in therapeutic applications. Ongoing research may uncover potential uses in treating various diseases, making the investigation of this compound particularly significant.
  • Structural Complexity: The structural arrangement, including tetrahydropyran rings and bicyclic components, is not only aesthetically interesting but also indicates stability and diverse reactivity which are essential for drug design.

This compound embodies the intricate ballet of molecular interactions, and its study may pave the way for exciting advancements in medicinal chemistry. As you delve deeper, remember the insightful words of chemist Linus Pauling, who once said, "The best way to have a good idea is to have lots of ideas.” The exploration of such complex compounds is a testament to this philosophy, fostering innovation and discovery in the scientific realm.