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Statine

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Identification
Molecular formula
C10H17NO4
CAS number
76896-32-7
IUPAC name
(2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-pyrrolidine-2-carboxylic acid
State
State

At room temperature, Statine is a solid. It is primarily utilized in research and pharmaceutical industries, often in its powder form for its role in peptide synthesis and enzyme inhibition studies.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
283.00
Boiling point (Kelvin)
556.15
General information
Molecular weight
215.25g/mol
Molar mass
179.2110g/mol
Density
1.1228g/cm3
Appearence

Statine is typically a white to off-white crystalline solid. As a non-proteinogenic amino acid derivative, it is often available in powder form in laboratory and industrial settings.

Comment on solubility

Solubility Characteristics

The solubility of (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-pyrrolidine-2-carboxylic acid is a fascinating subject due to its multi-functional characteristics. This compound contains multiple carboxylic acid groups, which significantly influence its solubility in various solvents.

Key Factors Affecting Solubility:

  • Polarity: The carboxylic acid groups contribute to the compound's overall polarity, enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules increases the solubility further, facilitating better interaction with the solvent.
  • Chain Structure: The isopropenyl group may introduce hydrophobic characteristics, potentially lowering solubility in non-polar solvents.

In typical scenarios, you can expect:

  • High solubility in aqueous solutions due to the presence of two carboxylic acid groups.
  • Moderate to low solubility in organic solvents such as hexane or chloroform because of its polar nature.

In summary, the solubility profile of this compound portrays a balance between its polar and non-polar regions, making it an interesting subject for studies focusing on drug formulation and biochemical interactions.

Interesting facts

Interesting Facts about (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-pyrrolidine-2-carboxylic acid

This fascinating compound is a member of the family of amino acids and has garnered attention in various scientific fields. Its unique structure features a pyrrolidine ring, which is a five-membered saturated ring containing nitrogen. Here are some compelling aspects of this compound:

  • Biological Relevance: This compound plays a significant role in biological processes and has been studied for its potential impact on metabolic pathways, particularly in relation to amino acid biosynthesis.
  • Potential Applications: Due to its structural characteristics, it may have applications in the pharmaceutical industry, especially in the design of new drugs targeting various diseases.
  • Chirality: The presence of multiple stereocenters (indicated by the S configurations) introduces significant chirality, which is crucial in biological systems where often only one enantiomer is bioactive.
  • Research Interest: Scientists are continuously searching for innovative methods to synthesize such compounds more efficiently, leading to advancements in organic chemistry.
  • Interdisciplinary Connections: This compound connects various fields, including organic chemistry, biochemistry, and pharmacology, demonstrating the interdisciplinary nature of modern scientific research.

"Understanding the nuances of compounds like (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-pyrrolidine-2-carboxylic acid can unlock new avenues in drug discovery and development."

In summary, the exploration of (2S,3S,4S)-3-(carboxymethyl)-4-isopropenyl-pyrrolidine-2-carboxylic acid represents a captivating intersection of chemistry and biology, offering potential insights into the molecular foundations of life and innovative solutions in medicine.

Synonyms
kainic acid
487-79-6
Digenin
Digenic acid
Helminal
Kainate
L-alpha-Kainic acid
Acide kainique
Acido kainico
alpha-Kainic acid
Digensaeure
Kainsaeure
Acidum kainicum
(2S,3S,4S)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid
alpha- Kainic acid
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S,3S,4S)-
CHEMBL275040
SIV03811UC
DTXSID7040526
CHEBI:31746
2-Carboxy-4-isopropenyl-3-pyrrolidineacetic acid
3-Pyrrolidineacetic acid, 2-carboxy-4-isopropenyl-
(2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidine-2-carboxylic acid
NSC136038
NSC-759587
3-(Carboxymethyl)-4-isopropenylproline
NCGC00024504-05
(3S,4R)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-L-proline
2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine
NSC 136038
(2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
(-)-A-KAINIC ACID
DTXCID5020526
(3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-yl-L-proline
Kainic acid [INN:JAN]
4071-38-9
CAS-487-79-6
Acide kainique [INN-French]
Acido kainico [INN-Spanish]
Acidum kainicum [INN-Latin]
SR-01000075454
BRN 0086660
UNII-SIV03811UC
kainic-acid
DL-Kainic acid
NSC-136038
KAI
1p1n
KAINIC ACID [MI]
WRW5P6M3EM
Biomol-NT_000217
KAINIC ACID [INN]
UPCMLD-DP146
Kainic acid, (+/-)-
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-
Lopac0_000656
SCHEMBL15777
4-22-00-01523 (Beilstein Handbook Reference)
MLS001074661
KAINIC ACID [WHO-DD]
BPBio1_001306
(-)-(.alpha.)-Kainic Acid
UPCMLD-DP146:001
UPCMLD-DP146:002
HMS2233K05
HMS3262C13
HMS3266C11
HMS3411A21
HMS3675A21
AAA48779
EX-A8001
HY-N2309
Tox21_110905
Tox21_500656
BDBM50002369
Kainic Acid - CAS 487-79-6
AKOS024456995
Tox21_110905_1
CCG-204742
LP00656
SDCCGSBI-0050635.P002
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2-alpha,3-beta,4-beta))-
NCGC00024504-02
NCGC00024504-03
NCGC00024504-04
NCGC00024504-06
NCGC00024504-07
NCGC00024504-08
NCGC00024504-09
NCGC00024504-15
NCGC00261341-01
DA-64702
SMR000471885
CS-0020451
EU-0100656
NS00075498
K 0250
Q390239
SR-01000597728
SR-01000075454-1
SR-01000075454-5
SR-01000075454-6
SR-01000075454-7
SR-01000597728-1
BRD-K52459018-001-09-1
rel-(3R,4R)-3-(carboxymethyl)-4-isopropenyl-D-proline
2S-CARBOXY-4S-(1-METHYLETHENYL)-3S-PYRROLDINEACETIC ACID
L-proline, 3-(carboxymethyl)-4-(1-methylethenyl)-, (3S,4S)-
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2R,3R,4R)-rel-
(2S-(2.ALPHA.,3.BETA.,4.BETA.))-2-CARBOXY-4-(1-METHYLETHENYL)-3-PYRROLIDINEACETIC ACID
InChI=1/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s