Skip to main content

Erythromycin

ADVERTISEMENT
Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
(2S,3S,4S,5R,6R)-6-[[(4S,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid
State
State

Erythromycin is typically a solid at room temperature. It is available as a crystalline powder that is used in various pharmaceutical formulations.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9390g/mol
Density
1.2400g/cm3
Appearence

Erythromycin is generally seen as a white or slightly yellowish crystalline powder. It is known for being a bit hygroscopic and may have a faint, characteristic odor.

Comment on solubility

Solubility Characteristics

The solubility of the compound (2S,3S,4S,5R,6R)-6-[[(4S,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid can be intriguingly complex due to its structural features. This compound exhibits properties that suggest variable solubility depending on the solvent used:

  • Polar Solvents: It is likely to be more soluble in polar solvents such as water and methanol due to the presence of multiple hydroxyl (-OH) groups and a carboxylic acid functional group. These polar functionalities can form hydrogen bonds with solvent molecules.
  • Non-Polar Solvents: Conversely, solubility in non-polar solvents such as hexane or octanol is expected to be low. The extensive hydrogen bonding capabilities of the compound render it less compatible in hydrophobic environments.
  • pH Influence: The solubility might also be influenced by the pH of the solution, as the carboxylic acid group can dissociate in alkaline conditions, potentially increasing solubility.
  • Temperature Effect: Increased temperature often enhances the solubility of organic compounds in solvents; therefore, examining solubility at different temperatures may yield interesting insights.

In summary, the solubility of this compound is significantly affected by the solvent's polarity, pH level, and temperature, which can lead to diverse implementation in various scientific applications.

Interesting facts

Interesting Facts about (2S,3S,4S,5R,6R)-6-[[(4S,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

This fascinating compound, often referred to in scientific literature, belongs to a class of complex natural products that exhibit significant pharmacological properties. Here are some engaging facts that highlight its importance:

  • Natural Product Origins: Many compounds such as this one are derived from natural sources, showcasing the intricate relationships between plants and their biochemical constituents.
  • Biological Activity: This compound has been studied for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties, making it a candidate for therapeutic applications.
  • Chirality: The complex stereochemistry, with multiple chiral centers, underscores the significance of chirality in drug design as different enantiomers can have vastly different effects in biological systems.
  • Structure-Activity Relationship: Research into this compound may provide insights into how structural changes can affect its biological activity, an essential consideration in medicinal chemistry.
  • Synergy with Other Compounds: Investigations into this compound often focus on its interactions with other molecules, particularly in the context of herbal medicine where multiple constituents can work together to enhance therapeutic effects.

As a scientist or student, studying such compounds can ignite a passion for discovering how complex natural chemical structures can lead to significant benefits in health and medicine. The ongoing research in this area emphasizes the intertwined nature of chemistry and biology, where understanding the subtleties of molecular interactions can lead to breakthroughs in treating diseases.