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Phorbol

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Identification
Molecular formula
C20H28O6
CAS number
17673-25-5
IUPAC name
(2S,4R,6R,8S,11S,12R)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,9,13-trimethyl-6-phenyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
State
State

At room temperature, Phorbol is typically found in a solid state. Its solid nature is characterized by its crystalline structure, which is evident in both its pure and derivative forms, such as esters which are commonly used in laboratory settings.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
440.00
Boiling point (Kelvin)
713.00
General information
Molecular weight
380.44g/mol
Molar mass
380.4350g/mol
Density
1.1805g/cm3
Appearence

Phorbol is typically a colorless or pale-yellow crystalline solid. It is known for its appearance in resin forms and is often utilized in biochemistry for research purposes due to its role as a potent activator of protein kinase C.

Comment on solubility

Solubility of (2S,4R,6R,8S,11S,12R)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,9,13-trimethyl-6-phenyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

The solubility characteristics of this intricate compound are influenced by its unique molecular structure. Understanding its solubility can be vital for its applications, including medicinal and industrial purposes. Here are some key points regarding its solubility:

  • Polarity: The presence of functional groups, such as hydroxy and acetyl groups, suggests that this compound exhibits polar characteristics. Polar compounds generally tend to dissolve in polar solvents.
  • Solvent Type: It is likely to have better solubility in solvents like ethanol, methanol, and possibly water due to the hydrophilic nature of the hydroxyl groups.
  • Hydrophobic Interactions: On the other hand, the presence of large hydrophobic portions in its structure may cause limited solubility in purely polar solvents, allowing for potential solubility in apolar solvents as well.
  • Concentration Factors: The solubility may also depend on concentration and temperature, as with many organic compounds.

In summary, while this compound likely shows some degree of solubility in polar solvents due to its functional groups, the overall solubility profile may vary significantly based on environmental conditions and specific solvent interactions.

Interesting facts

Interesting Facts about (2S,4R,6R,8S,11S,12R)-12-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,9,13-trimethyl-6-phenyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

This complex compound has a fascinating structure and potential applications in various fields of science. Here are some intriguing aspects:

  • Stereochemistry: The compound features multiple chiral centers, indicated by its (S) and (R) designations. These configurations can significantly affect the compound's biological activity and interactions, making it a valuable subject for study in stereochemistry.
  • Fluorine Atoms: The presence of a fluorine atom in the structure often increases the biological potency of compounds. It can enhance metabolic stability and influence lipophilicity, leading to improved absorption and bioavailability.
  • Functional Groups: The incorporation of hydroxy and acetyl groups serves to modify the compound's reactivity and solubility, suggesting potential applications in drug development or material science.
  • Natural Product Inspiration: Many complex natural products have similar structural features, hinting that this compound might mimic or influence biological pathways seen in nature.
  • Potential Therapeutic Uses: Given its intricate framework and unique functionalities, this compound could be investigated for various pharmacological effects, including anti-inflammatory or anti-cancer properties.

As a chemistry student or a scientist, delving into the synthesis and characterization of such a compound can provide profound insights into organic synthesis techniques and the interplay between structure and function in biochemical systems.

Whether you are focused on drug discovery, materials science, or exploring natural product chemistry, the exploration of compounds like this can illuminate novel pathways and innovations in research.

Synonyms
NS00121847