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Penicillin G

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Identification
Molecular formula
C16H18N2O4S
CAS number
61-33-6
IUPAC name
(2S,5R,6R)-6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, Penicillin G is most commonly found as a solid powder. It is essential in medical applications that it be dissolved in a solution for effective administration, usually via injection. The compound's solid state ensures stability until it is ready for use in pharmaceutical formulations.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
334.39g/mol
Molar mass
334.3910g/mol
Density
1.7000g/cm3
Appearence

Penicillin G is typically a white to off-white crystalline powder. It is known for being water-soluble, allowing it to be administered effectively in solution forms such as injections. In its pure form, it can appear as colorless needles or prisms, depending on the crystallization process.

Comment on solubility

Solubility of (2S,5R,6R)-6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of this complex compound can be considered intriguing and is influenced by a variety of factors:

  • Polarity: The presence of both polar and nonpolar functional groups in the molecular structure indicates that this compound's solubility may vary significantly in different solvents.
  • Hydrophobic interactions: The aromatic ring from the phenyl group can result in hydrophobic interactions, potentially decreasing solubility in aqueous solutions.
  • Amine functionality: The amino group may enhance solubility in polar solvents, promoting aqueous solubility through hydrogen bonding.
  • Solvent choice: Aqueous solubility may be greater in polar solvents, while organic solvents might see a different solubility profile due to competing interactions.

In summary, the solubility of (2S,5R,6R)-6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid requires careful consideration of its structural attributes and the surrounding environment. As quotes from solubility studies often emphasize, “Solubility is not merely about the chemical's nature; it also involves its interactions with the solvent.” Understanding these interactions can provide valuable insight into the compound's practical applications.

Interesting facts

Exploring (2S,5R,6R)-6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This fascinating compound belongs to a category of molecules known for their intricate structural features and biological significance. Here are some interesting facts about this compound:

  • Complex Structure: The molecule features a bicyclic system, which showcases the versatility of chemical bonding and spatial configuration in organic chemistry.
  • Biological Relevance: Compounds like this one often serve as important intermediates in the synthesis of pharmaceuticals, indicating its potential therapeutic applications.
  • Chirality: The presence of multiple stereocenters contributes to its chirality, allowing for the possibility of different enantiomers that may exhibit varying biological activities.
  • Functional Groups: This compound includes amine and carboxylic acid functional groups, which are pivotal in biochemistry as they can participate in important interactions within biological systems.

As a chemist, one might appreciate the synthetical challenges presented by this compound. Its unique thiazolidine ring contributes to its reactivity, providing avenues for modification and exploration in drug design. The substructure observed here highlights not only the beauty of organic molecules but also their potential to inspire advancements in medicine.

Renowned chemist, Linus Pauling, once stated, "The best way to have a good idea is to have a lot of ideas," a sentiment that perfectly applies to the exploration of complex compounds like this. Each investigation might unveil new pathways for innovative treatments or applications.

In the realm of synthetic chemistry, such compounds allow chemists to push the boundaries of knowledge, making them not just subjects of study, but also tools for discovery in the vast landscape of chemical science.

Synonyms
ST024772
DTXSID60274745
DTXCID00226203
33993-48-5
SCHEMBL3467975
AKOS024278947
(2S,5R,6R)-6-(2-amino-2-phenylacetylamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicy clo[3.2.0]heptane-2-carboxylic acid