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Mevastatin

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Identification
Molecular formula
C23H34O5
CAS number
73573-88-3
IUPAC name
(2S,6aR,6aS,8aR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
State
State

At room temperature, Mevastatin is in a solid state, presenting as a crystalline powder.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
390.54g/mol
Molar mass
390.5370g/mol
Density
1.2000g/cm3
Appearence

Mevastatin, also known as compactin, typically appears as a white crystalline powder. It may have a slight odor and a characteristic crystalline appearance under a microscope.

Comment on solubility

Solubility of (2S,6aR,6aS,8aR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid

The solubility of complex organic compounds like (2S,6aR,6aS,8aR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid can be influenced by several factors:

  • Polarity: The presence of carboxylic acid functional groups often enhances solubility in polar solvents such as water.
  • Hydrogen bonding: The ability of the compound to form hydrogen bonds with solvent molecules can significantly increase solubility.
  • Hydrophobic regions: Large hydrophobic hydrocarbon portions can lead to lower solubility in polar solvents, potentially causing a limited solubility.
  • pH levels: The ionization state of the carboxylic acid may vary with pH, affecting its solubility—more ionized forms are typically more soluble in water.

This compound's complex structure suggests that while it may have some solubility in organic solvents, its solubility in water could be limited. The interactions between its polar and nonpolar segments create a unique behavior in terms of solubility, often requiring specific conditions to fully dissolve. Therefore, optimizing temperature and pH can be key factors to explore in solubility studies.

Interesting facts

Interesting Facts About (2S,6aR,6aS,8aR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid

This intriguing compound, often referred to for its complex structure, belongs to a class of organic molecules known for their diverse biological properties. Here are some engaging aspects of this compound:

  • Complex Structure: The chirality present in this compound indicates multiple stereocenters, making it a subject of interest in stereochemistry and its implications in drug design.
  • Biological Activity: Compounds like this often exhibit unique biological activities, leading to potential applications in pharmaceuticals, especially in targeting enzymes and receptors.
  • Natural Occurrence: Many compounds related to this structure are found in nature, particularly in various plant and fungal species, signalling their potential roles in ecology and evolution.
  • Research Potential: The compound's intricate arrangement of sodium atoms and carboxylic acid groups presents an exciting area for research, especially in organic synthesis and medicinal chemistry.
  • Industrial Applications: With increasing interest in bioactive molecules, this compound could find applications in the food, cosmetic, or agrochemical industries.

In addition, the nuances in its formulation speak volumes about the advanced techniques involved in organic synthesis. As researchers delve deeper into the functions and interactions of such compounds, they not only unlock therapeutic potential but also contribute to the ever-expanding knowledge in organic and medicinal chemistry.

Overall, the study of such complex compounds is a reminder of the intricacies of nature and the endless possibilities for scientific discovery.

Synonyms
CHEMBL276700
5697-56-3
(2S,4As,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
(2S,6aR,6aS,8aR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
AC-207
AKOS025401523