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Flutemetamol

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Identification
Molecular formula
C17H14ClNO4
CAS number
765922-62-1
IUPAC name
3-[1-(4-chlorophenyl)-3-oxo-butyl]-2-hydroxy-chromen-4-one
State
State

At room temperature, Flutemetamol is typically found in a solid state. It remains stable under normal conditions and is often handled and stored as a crystalline powder in research and application settings.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
454.20
Boiling point (Kelvin)
727.35
General information
Molecular weight
387.75g/mol
Molar mass
387.8170g/mol
Density
1.3886g/cm3
Appearence

Flutemetamol is generally found as a crystalline solid. It may appear as a white to off-white powder in its pure form. The appearance can vary slightly depending on the specific formulation or preparation method, but it typically does not exhibit any significant coloration.

Comment on solubility

Solubility of 3-[1-(4-chlorophenyl)-3-oxo-butyl]-2-hydroxy-chromen-4-one

The solubility of the compound 3-[1-(4-chlorophenyl)-3-oxo-butyl]-2-hydroxy-chromen-4-one, often referred to as a flavonoid derivative, can be influenced by various factors including its molecular structure, polarity, and the presence of functional groups.

General Characteristics Affecting Solubility

  • Polarity: The presence of hydroxyl groups typically increases solubility in polar solvents like water.
  • Functional Groups: The chlorophenyl moiety may introduce hydrophobic characteristics, which can affect solubility.
  • Molecular Weight: Higher molecular weight can correlate with decreased solubility in certain solvents.

In many cases, compounds that exhibit both hydrophilic (due to hydroxyl groups) and hydrophobic (due to chlorophenyl groups) characteristics demonstrate variable solubility. It is essential to note that:

  • In aqueous environments, solubility may be limited, leading to a tendency to precipitate.
  • Solubility can profoundly vary among organic solvents, often showing a marked increase in non-polar solvents.

Ultimately, for detailed applications and practical usage, conducting solubility tests in specific solvents is recommended to establish precise solubility values.

Interesting facts

Interesting Facts about 3-[1-(4-chlorophenyl)-3-oxo-butyl]-2-hydroxy-chromen-4-one

This fascinating compound, known as a derivative of flavonoids, holds significant interest in both chemistry and pharmaceutical research due to its diverse biological activities. Here are some intriguing aspects to consider:

  • Bioactivity: The compound has been studied for its potential therapeutic effects, showing promise as an anti-inflammatory and antioxidant agent.
  • Structure-Activity Relationship: Its unique structural features, particularly the 4-chlorophenyl group, play a crucial role in enhancing its biological properties. Modifications to the structure can significantly alter its activity levels.
  • Synthesis: The synthesis of this molecule involves multistep procedures which can provide valuable insights into designing analogs with improved efficacy and selectivity.
  • Applications: With its potential applications in drug development, this compound is a subject of interest in medicinal chemistry, especially for diseases linked to oxidative stress and inflammation.
  • Natural Versus Synthetic: While flavonoids are commonly found in various plants and foods, this synthetic derivative allows for the investigation of specific biological effects that may not occur with natural compounds.

As stated by one prominent researcher, "The exploration of flavonoid derivatives like this one opens new avenues for developing effective therapeutic agents against chronic diseases."

In summary, the study of 3-[1-(4-chlorophenyl)-3-oxo-butyl]-2-hydroxy-chromen-4-one exemplifies the intersection of chemistry and biology, making it a compelling subject for investigation in both fields. Its combination of structural complexity and potential health benefits truly marks it as a noteworthy compound in contemporary science.