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Acetamidine derivative

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Identification
Molecular formula
C10H12ClN3S
CAS number
59277-89-3
IUPAC name
3-[1-(4-chlorophenyl)ethylideneamino]isothiourea
State
State

At room temperature, this compound is typically in a solid state.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
242.00
Boiling point (Kelvin)
515.15
General information
Molecular weight
229.71g/mol
Molar mass
229.7100g/mol
Density
1.3400g/cm3
Appearence

This compound typically appears as a crystalline solid with a white to off-white color.

Comment on solubility

Solubility of 3-[1-(4-chlorophenyl)ethylideneamino]isothiourea

The solubility of 3-[1-(4-chlorophenyl)ethylideneamino]isothiourea can be influenced by several factors, including its molecular structure and intermolecular interactions. Generally speaking, the ability of a compound to dissolve in a solvent is primarily determined by the following:

  • Polarity: Solubility tends to increase with polarity. Isothioureas often possess polar functional groups, which can enhance their solubility in polar solvents like water or alcohol.
  • Hydrogen Bonding: The presence of amino groups can facilitate hydrogen bonding with solvents, further enhancing solubility.
  • Temperature: Increasing temperature often increases solubility, as higher kinetic energy helps break solute-solute interactions.
  • pH Influence: The solubility of amines can vary with pH; in acidic conditions, protonation can increase solubility in water.

However, despite these general principles, the specific solubility of this compound may be less straightforward due to its complex structure, which includes a chlorophenyl moiety that can affect its interaction with solvents. For practical purposes, the solubility might require empirical determination through experimentation. In conclusion, understanding the solubility of 3-[1-(4-chlorophenyl)ethylideneamino]isothiourea involves considering its unique chemical characteristics as well as external factors such as solvent type and environmental conditions.

Interesting facts

Exciting Insights into 3-[1-(4-chlorophenyl)ethylideneamino]isothiourea

3-[1-(4-chlorophenyl)ethylideneamino]isothiourea is a fascinating compound that showcases the diverse world of organic chemistry. This compound belongs to a class of isothioureas, which are known for their unique structural characteristics and versatile applications. Here are some essential facts that highlight its significance:

  • Versatility in Synthesis: Isothioureas are valuable in synthetic organic chemistry. They can act as intermediates, allowing chemists to create a variety of complex molecules.
  • Biological Applications: Compounds like this one have shown potential in medicinal chemistry, particularly in drug development. The modifications made to the isothiourea structure can influence biological activity.
  • Mechanistic Studies: The presence of the 4-chlorophenyl group in its structure makes it an interesting subject for mechanistic studies, especially in exploring how substituents affect reactivity and selectivity.
  • Environmental Impact: Understanding compounds such as this can help in studying their behavior in ecological systems, as their interactions may have implications for environmental chemistry.

As a chemist or student delving into organic compounds, exploring 3-[1-(4-chlorophenyl)ethylideneamino]isothiourea opens up numerous discussions regarding reactivity, synthesis, and application in pharmacology. The compound serves as a reminder of the intricate relationships between molecular structure and function, providing a captivating roadmap for ongoing research and innovation.

In the words of a notable chemist, "The beauty of chemistry lies not just in the compounds we create, but in the infinite possibilities they present."