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Cloriflucumarol

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Identification
Molecular formula
C18H15ClO3
CAS number
104432-65-3
IUPAC name
3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one
State
State

The compound is a solid at room temperature, typically presenting as a crystalline powder.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
417.40
Boiling point (Kelvin)
690.55
General information
Molecular weight
316.78g/mol
Molar mass
316.7780g/mol
Density
1.3250g/cm3
Appearence

Cloriflucumarol typically appears as a crystalline solid that is white to off-white in color.

Comment on solubility

Solubility of 3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one

The compound 3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one, known for its unique structural features, exhibits specific solubility properties that may influence its applications in various fields.

In terms of solubility:

  • Solvent-dependent solubility: This compound is expected to be more soluble in organic solvents such as dichloromethane and ethanol due to its hydrophobic aromatic system.
  • Moderate water solubility: Its solubility in water may be somewhat limited, typically arising from the presence of hydrophilic hydroxyl (-OH) groups that offer some degree of interaction with water.
  • Temperature effect: Like many organic compounds, solubility may increase with temperature, allowing for better dissolution in organic solvents when heated.

In summary, the solubility characteristics of 3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one clearly depend on the solvent and conditions used. Understanding these solubility behaviors is essential for optimizing the compound's utilization in practical applications.

Interesting facts

Interesting Facts about 3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one

3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one, commonly recognized for its unique structural framework, belongs to the flavonoid family, a group celebrated for their diverse biological activities. This compound showcases the fascinating interplay between chemistry and biology, making it a subject of interest for both researchers and students alike.

Structural Highlights

  • Chromone Core: The molecule features a chromone structure, which is a key component in numerous flavonoids, leading to various pharmacological properties.
  • Chlorophenyl Group: The inclusion of a 4-chlorophenyl group enhances the compound's lipophilicity, potentially affecting its bioactivity and interaction with biological systems.
  • Hydroxyl Group: The presence of the hydroxyl group at the 2-position is crucial for contributing to its antioxidant activities.

Biological Relevance

This compound has drawn attention due to its potential therapeutic effects, which include:

  • Antioxidant Activity: Compounds with hydroxyl substitutions are often recognized for neutralizing free radicals, thereby reducing oxidative stress.
  • Anti-inflammatory Properties: Preliminary studies suggest that flavonoids can modulate inflammatory pathways, positioning this compound as a promising candidate in anti-inflammatory research.
  • Anticancer Potential: Some derivates in the flavonoid class, including those related to this compound, have shown cytotoxic effects against various cancer cell lines.

Applications and Future Prospects

With its impressive profile, 3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one paves the way for numerous applications:

  • Pharmaceuticals: Such compounds are frequently explored in drug development for conditions ranging from allergies to cancer.
  • Food Industry: As antioxidants, they may be utilized in preserving food quality and enhancing health benefits.
  • Cosmetics: Their skin-protective properties have led to interest in their incorporation into cosmetic formulations.

In conclusion, the multi-faceted nature of 3-[1-(4-chlorophenyl)propyl]-2-hydroxy-chromen-4-one makes it a captivating subject for ongoing chemical and pharmacological research, embodying a perfect amalgamation of structure and function. As noted by researchers, "Understanding the nuances of such compounds may unlock new frontiers in medicine and health." This compound indeed holds the potential for significant advancements in the field.